Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Filippo Scialó"'
Autor:
Fabio Perrotta, Vito D’Agnano, Domenica Francesca Mariniello, Giuseppe Castaldo, Maria Vitale, Mario Cazzola, Andrea Bianco, Filippo Scialò
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a debilitating and progressive lung disease of unknown aetiology, characterized by the relentless deposition of fibrotic tissue. Biomarkers may play a pivotal role as indicators of disease pr
Externí odkaz:
https://doaj.org/article/bf41a9fac35340c8a08593f6d5689615
Autor:
Iolanda Cioffi, Olivia Di Vincenzo, Nicola Imperatore, Mariagrazia Fisco, Anna Testa, Filippo Scialò, Fabiana Castiglione, Margherita Ruoppolo, Fabrizio Pasanisi, Lidia Santarpia
Publikováno v:
Frontiers in Nutrition, Vol 10 (2023)
IntroductionCrohn’s disease (CD) is an immune-mediated inflammatory disorder of the gastrointestinal tract with a relapsing–remitting course. Amino acids (AAs) may play critical roles in the intestinal manifestations of disease, due to their invo
Externí odkaz:
https://doaj.org/article/90aae11ed7bb45929c6458d893db7ade
Autor:
Maria Vitale, Filippo Scialò, Margherita Passariello, Eleonora Leggiero, Anna D’Agostino, Lorella Tripodi, Laura Gentile, Andrea Bianco, Giuseppe Castaldo, Vincenzo Cerullo, Claudia De Lorenzo, Lucio Pastore
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Oncolytic virotherapy is an emerging therapeutic approach based on replication-competent viruses able to selectively infect and destroy cancer cells, inducing the release of tumor-associated antigens and thereby recruiting immune cells with a subsequ
Externí odkaz:
https://doaj.org/article/6f477dd76d89467589949198f41c19a7
Autor:
Ersilia Nigro, Marco Mosella, Aurora Daniele, Marta Mallardo, Mariasofia Accardo, Andrea Bianco, Fabio Perrotta, Filippo Scialò
Publikováno v:
Life, Vol 13, Iss 2, p 444 (2023)
Chronic obstructive pulmonary disease (COPD) is characterized by respiratory symptoms and non-reversible airflow limitation with recurrent episodes of acute exacerbations. The concurrent presence of bronchiectasis in patients with COPD is associated
Externí odkaz:
https://doaj.org/article/1f97481485b6464abc2ba724cbc9eb07
Autor:
Vito D’Agnano, Filippo Scialò, Francesco Perna, Lidia Atripaldi, Stefano Sanduzzi, Valentino Allocca, Maria Vitale, Lucio Pastore, Andrea Bianco, Fabio Perrotta
Publikováno v:
Life, Vol 12, Iss 8, p 1141 (2022)
COVID-19 encompasses a broad spectrum of clinical conditions caused by SARS-CoV-2 infection. More severe cases experience acute respiratory and/or multiorgan failure. KL-6 is a glycoprotein expressed mainly from type II alveolar cells with pro-fibrot
Externí odkaz:
https://doaj.org/article/13e9069966fd458c829119ac2be81246
Biomarkers of Endothelial Damage in Distinct Phases of Multisystem Inflammatory Syndrome in Children
Autor:
Monica Gelzo, Antonietta Giannattasio, Marco Maglione, Stefania Muzzica, Carolina D’Anna, Filippo Scialò, Thaililja Gagliardo, Michela Grieco, Vincenzo Tipo, Giuseppe Castaldo
Publikováno v:
Metabolites, Vol 12, Iss 8, p 680 (2022)
Endothelial hyperinflammation and vasculitis are known hallmarks of acute COVID-19 and multisystem inflammatory syndrome in children (MIS-C). They are due to the direct effect of the virus on endothelial cells enhanced by pro-inflammatory modulators
Externí odkaz:
https://doaj.org/article/dd9c185465d44eafb08b1ca351d4211a
Autor:
Monica Gelzo, Filippo Scialò, Sara Cacciapuoti, Biagio Pinchera, Annunziata De Rosa, Gustavo Cernera, Marika Comegna, Lorella Tripodi, Nicola Schiano Moriello, Mauro Mormile, Gabriella Fabbrocini, Roberto Parrella, Gaetano Corso, Ivan Gentile, Giuseppe Castaldo
Publikováno v:
Viruses, Vol 14, Iss 3, p 534 (2022)
Profound clinical differences between the first and second waves of COVID-19 were observed in Europe. Nitric oxide (NO) may positively impact patients with Severe Acute Respiratory Syndrome CoronaVirus-2 (SARS-CoV-2) infection. It is mainly generated
Externí odkaz:
https://doaj.org/article/988a69c41adb4044a6e50cd1de951f38
Autor:
Filippo Scialò, Ashwin Sriram, Rhoda Stefanatos, Ruth V. Spriggs, Samantha H.Y. Loh, L. Miguel Martins, Alberto Sanz
Publikováno v:
Redox Biology, Vol 32, Iss , Pp - (2020)
Reactive Oxygen Species (ROS) are essential cellular messengers required for cellular homeostasis and regulate the lifespan of several animal species. The main site of ROS production is the mitochondrion, and within it, respiratory complex I (CI) is
Externí odkaz:
https://doaj.org/article/19ecc0b6012c48ba9888fe74cef8cc9d
Autor:
Filippo Scialo, Felice Amato, Gustavo Cernera, Monica Gelzo, Federica Zarrilli, Marika Comegna, Lucio Pastore, Andrea Bianco, Giuseppe Castaldo
Publikováno v:
Life, Vol 11, Iss 2, p 94 (2021)
The defective mucociliary clearance due to CFTR malfunctioning causes predisposition to the colonization of pathogens responsible for the recurrent inflammation and rapid deterioration of lung function in patients with cystic fibrosis (CF). This has
Externí odkaz:
https://doaj.org/article/4d27c7f5f8e24d7f97e2c4076c8576e3
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Reactive Oxygen Species (ROS) can cause oxidative damage and have been proposed to be the main cause of aging and age-related diseases including cancer, diabetes and Parkinson's disease. Accordingly, mitochondria from old individuals have higher leve
Externí odkaz:
https://doaj.org/article/285ab1a4568d4c40b297223f498cb858