Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Filippo S. Giorgi"'
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 9, Pp 10180-10199 (2024)
Neuromodulatory subcortical systems (NSSs) are monoaminergic and cholinergic neuronal groups that are markedly and precociously involved in the pathogenesis of many neurodegenerative disorders (NDDs), including Parkinson’s and Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/a7f81bdd08cf412bb7b6a155c2c948c6
Autor:
Francesca Biagioni, Anderson Gaglione, Filippo S. Giorgi, Domenico Bucci, Slavianka Moyanova, Antonio De Fusco, Michele Madonna, Francesco Fornai
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 76-94 (2019)
Status epilepticus (SE) of limbic onset might cause degenerative phenomena in different brain structures, and may be associated with chronic cognitive and EEG effects. In the present study SE was evoked focally by microinfusing picomolar doses of cyc
Externí odkaz:
https://doaj.org/article/fd8f09c80ee24a80b4765750cdddfb1f
Autor:
Gloria Lazzeri, Carla L. Busceti, Francesca Biagioni, Cinzia Fabrizi, Gabriele Morucci, Filippo S. Giorgi, Michela Ferrucci, Paola Lenzi, Stefano Puglisi-Allegra, Francesco Fornai
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7232 (2021)
Norepinephrine (NE) neurons and extracellular NE exert some protective effects against a variety of insults, including methamphetamine (Meth)-induced cell damage. The intimate mechanism of protection remains difficult to be analyzed in vivo. In fact,
Externí odkaz:
https://doaj.org/article/80d64094c18742139e32d9242b5a302c
Publikováno v:
Frontiers in Neuroanatomy, Vol 13 (2019)
Externí odkaz:
https://doaj.org/article/8fba843ac23c401faeb1db250d8a0c65
Autor:
Filippo S. Giorgi, Larisa Ryskalin, Riccardo Ruffoli, Francesca Biagioni, Fiona Limanaqi, Michela Ferrucci, Carla L. Busceti, Ubaldo Bonuccelli, Francesco Fornai
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
Alzheimer’s Disease (AD) features the accumulation of β-amyloid and Tau aggregates, which deposit as extracellular plaques and intracellular neurofibrillary tangles (NFTs), respectively. Neuronal Tau aggregates may appear early in life, in the abs
Externí odkaz:
https://doaj.org/article/02055fa097ec402898f3d82f41a3ccb6
Autor:
Giada Frenzilli, Larisa Ryskalin, Michela Ferrucci, Emanuela Cantafora, Silvia Chelazzi, Filippo S. Giorgi, Paola Lenzi, Vittoria Scarcelli, Alessandro Frati, Francesca Biagioni, Stefano Gambardella, Alessandra Falleni, Francesco Fornai
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2017)
Exposure to loud noise is a major environmental threat to public health. Loud noise exposure, apart from affecting the inner ear, is deleterious for cardiovascular, endocrine and nervous systems and it is associated with neuropsychiatric disorders. I
Externí odkaz:
https://doaj.org/article/c4bb4865930a4f258e7381a6ee1af25c
Autor:
Filippo S. Giorgi, Fabio Blandini, Emanuela Cantafora, Francesca Biagioni, Marie-Therese Armentero, Livia Pasquali, Francesco Orzi, Luigi Murri, Antonio Paparelli, Francesco Fornai
Publikováno v:
Neurobiology of Disease, Vol 30, Iss 3, Pp 388-399 (2008)
The noradrenergic nucleus Locus Coeruleus (LC) densely innervates limbic structures. In rats, the damage to LC by the neurotoxin DSP-4, converts episodic limbic seizures induced by bicuculline infusion in the anterior piriform cortex (APC) into self-
Externí odkaz:
https://doaj.org/article/acba08fabaf146c8806113bd17e15bef
Publikováno v:
Neurobiology of Disease, Vol 25, Iss 1, Pp 73-79 (2007)
GABAergic activation of substantia nigra pars reticulata (SNR) at postnatal day (PN) 15 has sex-specific features on seizure control in vivo and electrophysiological responses in vitro. In males, the GABAA-receptor agonist muscimol has proconvulsant
Externí odkaz:
https://doaj.org/article/63541ea83ee84210b3ee2e15f46ca172
Publikováno v:
Neurobiology of Disease, Vol 18, Iss 2, Pp 346-355 (2005)
Repetitive behaviors (such as circling) are one of the defining features of autism. The substantia nigra (SN) is involved in circling. We used unilateral SN pars reticulata (SNR) infusions of the GABA agonist muscimol to induce circling and deoxygluc
Externí odkaz:
https://doaj.org/article/a2929e63401448c8a0c989b1933a776f
Autor:
Gayane Aghakhanyan, Alessandro Galgani, Andrea Vergallo, Francesco Lombardo, Nicola Martini, Filippo Baldacci, Gloria Tognoni, Andrea Leo, Federica Guidoccio, Gabriele Siciliano, Francesco Fornai, Nicola Pavese, Duccio Volterrani, Filippo S. Giorgi
Publikováno v:
Neurobiology of Aging. 122:12-21
Locus Coeruleus (LC) degeneration occurs early in Alzheimer's disease (AD) and this could affect several brain regions innervated by LC noradrenergic axon terminals, as these bear neuroprotective effects and modulate neurovascular coupling/neuronal a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb305367045c7ba57782678c5d15c33c
https://doi.org/10.1016/j.neurobiolaging.2022.11.002
https://doi.org/10.1016/j.neurobiolaging.2022.11.002