Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Filippo Prischi"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Externí odkaz:
https://doaj.org/article/f6bdad543892431faa4838dc4ec43fe1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The interaction between macromolecular proteins and small molecule ligands is an essential component of cellular function. Such ligands may include enzyme substrates, molecules involved in cellular signalling or pharmaceutical drugs. Together with bi
Externí odkaz:
https://doaj.org/article/0ef51fc8b5c94b60b1f1fce88618c681
Autor:
Ottavia Spiga, Vittoria Cicaloni, Cosimo Fiorini, Alfonso Trezza, Anna Visibelli, Lia Millucci, Giulia Bernardini, Andrea Bernini, Barbara Marzocchi, Daniela Braconi, Filippo Prischi, Annalisa Santucci
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 15, Iss 1, Pp 1-10 (2020)
Abstract Background Alkaptonuria (AKU) is an ultra-rare autosomal recessive disease caused by a mutation in the homogentisate 1,2-dioxygenase (HGD) gene. One of the main obstacles in studying AKU, and other ultra-rare diseases, is the lack of a stand
Externí odkaz:
https://doaj.org/article/7e00aa955b77490f827561462633086f
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Externí odkaz:
https://doaj.org/article/e9e85e88888d412a813e76e4b48701b2
Autor:
Irabonosi Obomighie, Kestutis Lapenas, Billy E. Murphy, Alexander M. C. Bowles, Ulrike Bechtold, Filippo Prischi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
The p70 ribosomal S6 kinase (S6K) family is a group of highly conserved kinases in eukaryotes that regulates cell growth, cell proliferation, and stress response via modulating protein synthesis and ribosomal biogenesis. S6Ks are downstream effectors
Externí odkaz:
https://doaj.org/article/000d409216894d388442893ef02ca841
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 3, Pp 6454-6466 (2013)
The unfolded protein response (UPR) is a cell-signaling system that detects the accumulation of unfolded protein within the endoplasmic reticulum (ER) and initiates a number of cellular responses to restore ER homeostasis. The presence of unfolded pr
Externí odkaz:
https://doaj.org/article/f25a31dbf34c423087b152fcdb5b436b
Publikováno v:
eLife, Vol 4 (2015)
The unfolded protein response (UPR) is an essential cell signaling system that detects the accumulation of misfolded proteins within the endoplasmic reticulum (ER) and initiates a cellular response in order to maintain homeostasis. How cells detect t
Externí odkaz:
https://doaj.org/article/5e74516079db4a84b1f56ab203f5f8ee
Autor:
Eleftheria Trampari, Filippo Prischi, Attilio V. Vargiu, Justin Abi-Assaf, Vassiliy N. Bavro, Mark A. Webber
Publikováno v:
npj Antimicrobials and Resistance. 1
Antibiotic resistance is a pressing healthcare challenge and is mediated by various mechanisms, including the active export of drugs via multidrug efflux systems, which prevent drug accumulation within the cell. Here, we studied how Salmonella evolve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d954242eb85ca9f73769a92bdc519c
https://doi.org/10.1038/s44259-023-00001-8
https://doi.org/10.1038/s44259-023-00001-8
Autor:
Stefano Barbera, Luisa Raucci, Giusy Tassone, Laura Tinti, Filippo Prischi, Annalisa Santucci, Maurizio Mongiat, Gian Marco Tosi, Federico Galvagni, Anna Dimberg, Cecilia Pozzi, Maurizio Orlandini
Blocking the signaling activated by the plasma membrane receptor CD93 has recently been demonstrated a useful tool in antiangiogenic treatment and oncotherapy. In the proliferating endothelium, CD93 regulates cell adhesion, migration, and vascular ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48f3700b815f6fef4799b8898cc0e175
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-495880
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-495880
The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance
Publikováno v:
Oncogene
Prostate cancer (PCa) is the second most commonly occurring cancer in men, with over a million new cases every year worldwide. Tumor growth and disease progression is mainly dependent on the Androgen Receptor (AR), a ligand dependent transcription fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4416beefbf30804a2906013edf8ad424
https://doi.org/10.1038/s41388-021-01810-9
https://doi.org/10.1038/s41388-021-01810-9