Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Filippo Pigazzani"'
Autor:
Filippo Pigazzani, Kenneth A. Dyar, Steve V. Morant, Céline Vetter, Amy Rogers, Robert W.V. Flynn, David A. Rorie, Isla S. Mackenzie, Francesco P. Cappuccio, Roberto Manfredini, Thomas M. MacDonald
Publikováno v:
EClinicalMedicine, Vol 72, Iss , Pp 102633- (2024)
Summary: Background: Timing drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening (TIME) clinical trial we examined whether timing of usual antihyper
Externí odkaz:
https://doaj.org/article/a781e7d7596a4327a6bf913674b77cc3
Autor:
Isla S Mackenzie, Christopher J Hawkey, Ian Ford, Nicola Greenlaw, Filippo Pigazzani, Amy Rogers, Allan D Struthers, Alan G Begg, Li Wei, Anthony J Avery, Jaspal S Taggar, Andrew Walker, Suzanne L Duce, Rebecca J Barr, Jennifer S Dumbleton, Evelien D Rooke, Jonathan N Townend, Lewis D Ritchie, Thomas M MacDonald
Publikováno v:
Health Technology Assessment, Vol 28, Iss 18 (2024)
Abstract Background Allopurinol is a xanthine oxidase inhibitor that lowers serum uric acid and is used to prevent acute gout flares in patients with gout. Observational and small interventional studies have suggested beneficial cardiovascular effect
Externí odkaz:
https://doaj.org/article/fe11fb9eb1a34d309ffcfa360082b971
Autor:
Thomas M MacDonald, Andrew Duncan, Amy Rogers, Greg Guthrie, Alex Doney, Steve Morant, Isla Mackenzie, Evelien Rooke, Rebecca Barr, Filippo Pigazzani, Krists Zutis
Publikováno v:
BMJ Open, Vol 12, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/ebbd5efdbcbf4f0f905443c0b51bec32
Autor:
Filippo Pigazzani, Davide Gorni, Kenneth A. Dyar, Matteo Pedrelli, Gwen Kennedy, Gabriele Costantino, Agostino Bruno, Isla Mackenzie, Thomas M. MacDonald, Uwe J. F. Tietge, Jacob George
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1541 (2022)
Oxidative stress participates in the development and exacerbation of cardiovascular diseases (CVD). The ability to promptly quantify an imbalance in an individual reductive-oxidative (RedOx) state could improve cardiovascular risk assessment and mana
Externí odkaz:
https://doaj.org/article/a0accbb73966423d96c1fc83daa20d07
Autor:
Filippo Pigazzani
Publikováno v:
Archive of Clinical Cases. 9:41-49
Mitral annular disjunction is related to increased arrhythmogenic risk; in a certain percentage of cases, mitral annular disjunction is associated with tricuspid annular disjunction. While the prognostic implications of mitral annular disjunction hav
Autor:
Isla S Mackenzie, Christopher J Hawkey, Ian Ford, Nicola Greenlaw, Filippo Pigazzani, Amy Rogers, Allan D Struthers, Alan G Begg, Li Wei, Anthony J Avery, Jaspal S Taggar, Andrew Walker, Suzanne L Duce, Rebecca J Barr, Jennifer S Dumbleton, Evelien D Rooke, Jonathan N Townend, Lewis D Ritchie, Thomas M MacDonald, Husnat Ahmed, Peter Arthur, Jane Aziz, Lawrence Barnes, Sarah Boyle, Tom Brighton, Morris Brown, Mark Caulfield, Jesse Dawson, Martin Denvir, Alexander SF Doney, Sagar Doshi, Moira Dryburgh, Michael Eddleston, Jim Finlayson, Ahmet Fuat, Jacqueline Furnace, JW Kerr Grieve, Greg Guthrie, Sharon Ham, Emma Isaard, Claudine Jennings, Richard Johnson, Claire Kerr, Sohail Khan, Kailash Krishnan, Susan Long, Anne Mackintosh, Mary Joan Macleod, Terry McCormack, Paul McEleny, Monique Morar, Adnan Nadir, David Newby, Colin Petrie, David Preiss, Stuart Ralston, Marc Randall, Helen Routledge, Saad Shakir, Raj Sharma, Bridget Shepherd, Don Sims, Gordon Snedden, Jasper Trevelyan, Christopher Weir, Robin Weir, Kirsty Wetherall, Robbie Wilson, Adam Wilson, Kris Zutis
Publikováno v:
Lancet (London, England). 400(10359)
Allopurinol is a urate-lowering therapy used to treat patients with gout. Previous studies have shown that allopurinol has positive effects on several cardiovascular parameters. The ALL-HEART study aimed to determine whether allopurinol therapy impro
Autor:
Amy Rogers, Evelien Rooke, Steve Morant, Greg Guthrie, Alex Doney, Andrew Duncan, Isla Mackenzie, Rebecca Barr, Filippo Pigazzani, Krists Zutis, Thomas M MacDonald
Publikováno v:
BMJ open. 12(6)
ObjectivesTo describe the incidence of adverse events (AEs), reactogenicity symptoms, menstrual changes and overall self-rated improvement in health and well-being after COVID-19 vaccination.DesignVAC4COVID is an ongoing prospective, active observati
Publikováno v:
British Journal of Clinical Pharmacology. 85:285-303
The aims of the current review were to compare the efficacy of monotherapy with bendroflumethiazide vs. indapamide on mortality, cardiovascular outcomes, blood pressure, need for intensification of treatment and treatment withdrawal. Two authors inde
Autor:
Margarida Goulart, Maryam Zare Jeddi, Filippo Pigazzani, Josephine McCourt, Yuri Bruinen de Bruin, Anne Sophie Lequarre, Claudio Colosio, Peter Clevestig
Publikováno v:
Safety science, 128:104773
Safety Science
Safety Science
This paper presents an analysis of risk mitigation measures taken by countries around the world facing the current COVID-19 outbreak. In light of the current pandemic the authors collated and clustered (using harmonised terminology) the risk mitigati
Pharmacogenomic Approach to Selecting Antiplatelet Therapy in Patients With Acute Coronary Syndromes
Autor:
Giorgia Paoli, Piera Angelica Merlini, Giampiero Patrizi, Angela Guidorossi, Marco Cereda, Antonio Crocamo, Paola Bevilacqua, Filippo Pigazzani, Mario Angelo Comelli, Caterina Caminiti, Guidantonio Malagoli Tagliazucchi, Diego Ardissino, Marco Bianchessi, Elisa Nicosia, Giuseppe Maglietta, Paolo Moruzzi, Giovanni Quinto Villani, Francesca Notarangelo
Publikováno v:
Journal of the American College of Cardiology. 71:1869-1877
Background Although clopidogrel is still frequently used in patients with acute coronary syndromes (ACS), its efficacy is hampered by interpatient response variability caused by genetic polymorphisms associated with clopidogrel’s metabolism. Object