Výsledky vyhledávání - "Filippo Guglielmetti"

Adoption of immuno-oncology in NSCLC, a real-world study in EU5

Autor: Alejandra Martinez De Pinillos, Isabel Ricote Lobera, Roberto Jorge Bitton, Cristina Martinez, C. Anger, Filippo Guglielmetti

Publikováno v: Journal of Clinical Oncology. 37:e20631-e20631

e20631 Background: To date, there are no robust studies in real world practice describing the use of IO (immuno-oncology) treatments in advanced/metastatic (adv/m) NSCLC. The available evidence in Europe is limited to observational studies of small s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f43101f86dc1d11b21feb9728ce4217c
https://doi.org/10.1200/jco.2019.37.15_suppl.e20631

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Patterns of care and of biomolecular characterization of right, transverse, and left colorectal cancer from real-life evidence in Asia Pacific and European countries

Autor: Filippo Guglielmetti, P. Nasuti, S. Mpima, Ettore Mari

Publikováno v: Annals of Oncology. 29:viii195-viii196

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae431bb52c557619708a696d8d9c4d97
https://doi.org/10.1093/annonc/mdy281.133

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Profiling and treatment patterns in NSCLC patients with CNS (brain) metastases in Europe and Asia

Autor: Ettore Mari, Fil Manuguid, P. Nasuti, Sari H. Enschede, Filippo Guglielmetti, Sheila Mpima

Publikováno v: Journal of Clinical Oncology. 36:e21085-e21085

e21085Background: Between 25% and 40% of NSCLC patients develop CNS metastases, a high unmet medical need with median survivals of 3–14 months. Using a large oncology real-world patient database, w...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ca083993fa6261800eb540260359e6f0
https://doi.org/10.1200/jco.2018.36.15_suppl.e21085

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Differential Expression of S100β and Glial Fibrillary Acidic Protein in the Hippocampus after Kainic Acid-Induced Lesions and Mossy Fiber Sprouting in Adult Rat

Autor: Caterina Bendotti, Filippo Guglielmetti, Rosario Samanin, Warren D. Hirst, Massimo Tortarolo

Publikováno v: Experimental Neurology. 161:317-329

The expression of S100beta and glial fibrillary acidic protein (GFAP) was analyzed following bilateral injection of kainic acid (KA), a glutamate derivative, into the CA3 region of the adult rat hippocampus. This treatment produces a progressive dege

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::724c5408702b943ce1b1604139ee88d9
https://doi.org/10.1006/exnr.1999.7262

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Selective up-regulation of protein kinase Cϵ in granule cells after kainic acid-induced seizures in rat

Autor: Marcus Rattray, Caterina Bendotti, Filippo Guglielmetti, E Butelli, Rosario Samanin, S. Baldessari

Publikováno v: Molecular Brain Research. 49:188-196

Kainate-induced seizure activity causes persistent changes in the hippocampus that include synaptic reorganization and functional changes in the mossy fibers. Using in situ hybridization histochemistry, the expression of PKC alpha, PKC beta, PKC gamm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adab70cbc22e7a157ee491b478b869fa
https://doi.org/10.1016/s0169-328x(97)00142-3

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Relationship Between GAP-43 Expression in the Dentate Gyrus and Synaptic Reorganization of Hippocampal Mossy Fibres in Rats Treated with Kainic Acid

Autor: T Southgate, Caterina Bendotti, Rosario Samanin, Filippo Guglielmetti, Mario Pende, S. Baldessari

Publikováno v: European Journal of Neuroscience. 9:93-101

Kainic acid-induced seizures, in adult rats produce neurodegeneration in the hippocampus followed by sprouting of the mossy fibres in the inner molecular layer of the dentate gyrus and changes in GAP-43 expression in the granule cells. In the present

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc5a504845bcf1aec1729697ae03595
https://doi.org/10.1111/j.1460-9568.1997.tb01357.x

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Cycloheximide inhibits kainic acid-induced GAP-43 mRNA in dentate granule cells in rats

Autor: Filippo Guglielmetti, Rosario Samanin, Mario Pende, Caterina Bendotti

Publikováno v: Europe PubMed Central

We have previously shown that kainic acid-induced seizures in adult rats caused an up-regulation of GAP-43 mRNA in the granule cells of the hippocampus, suggesting an involvement of this protein in the kainic acid-induced sprouting of mossy fibres. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b93a2c6c2ce8f7e6be3992226854a53d
https://pubmed.ncbi.nlm.nih.gov/8981419

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Biochemical evidence of functional interaction between mu- and delta-opioid receptors in SK-N-BE neuroblastoma cell line

Autor: Antonio Groppetti, Daniela Amoroso, Elisabetta Palazzi, Elena L. M. Ceppi, Lidia Catozzi, Filippo Guglielmetti

Publikováno v: Journal of neurochemistry. 67(1)

Radioligand binding assays and functional experiments revealed that the SK-N-BE neuroblastoma cell line expresses a similar ratio of mu- and delta-opioid receptors, both negatively coupled to adenylyl cyclase through pertussis toxin-sensitive G prote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61387c3201ed69903137b1dfdbab304c
https://pubmed.ncbi.nlm.nih.gov/8666984

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