Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex

Autor: Filippo Ghezzi, Andre Marques-Smith, Paul G Anastasiades, Daniel Lyngholm, Cristiana Vagnoni, Alexandra Rowett, Gokul Parameswaran, Anna Hoerder-Suabedissen, Yasushi Nakagawa, Zoltan Molnar, Simon JB Butt

Publikováno v: eLife, Vol 10 (2021)

Subplate neurons (SPNs) are thought to play a role in nascent sensory processing in neocortex. To better understand how heterogeneity within this population relates to emergent function, we investigated the synaptic connectivity of Lpar1-EGFP SPNs th

Externí odkaz: https://doaj.org/article/c7d3e2030c9a4028b225ee22163067be

Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson’s disease

Autor: Gihan Weerasinghe, Peter Brown, Filippo Ghezzi, Andrea A. Kühn, Christian Bick, Gerd Tinkhauser, Benoit Duchet, Rafal Bogacz

Publikováno v: PLoS Computational Biology
Duchet, B, Ghezzi, F, Weerasinghe, G, Tinkhauser, G, Kühn, A A, Brown, P, Bick, C & Bogacz, R 2021, ' Average beta burst duration profiles provide a signature of dynamical changes between the on and off medication states in Parkinson's disease ', PLoS Computational Biology, vol. 17, no. 7, e1009116 . https://doi.org/10.1371/journal.pcbi.1009116
PLoS Computational Biology, 17(7):e1009116. Public Library of Science
Duchet, Benoit; Ghezzi, Filippo; Weerasinghe, Gihan; Tinkhauser, Gerd; Kühn, Andrea A; Brown, Peter; Bick, Christian; Bogacz, Rafal (2021). Average beta burst duration profiles provide a signature of dynamical changes between the ON and OFF medication states in Parkinson's disease. PLoS computational biology, 17(7), e1009116. Public Library of Science 10.1371/journal.pcbi.1009116
PLoS Computational Biology, Vol 17, Iss 7, p e1009116 (2021)

Parkinson’s disease motor symptoms are associated with an increase in subthalamic nucleus beta band oscillatory power. However, these oscillations are phasic, and there is a growing body of evidence suggesting that beta burst duration may be of cri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eab6d6960d461a042ce2d1f46a67e5f
https://ora.ox.ac.uk/objects/uuid:1d49a370-d4fa-41e6-a026-ac183267e36b

Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex

Autor: Anna Hoerder-Suabedissen, Yasushi Nakagawa, Andre Marques-Smith, Filippo Ghezzi, Zoltán Molnár, Alexandra Rowett, Simon J. B. Butt, Daniel Lyngholm, Gokul Parameswaran, Paul G. Anastasiades, Cristiana Vagnoni

Publikováno v: eLife, Vol 10 (2021)
Ghezzi, F, Marques-Smith, A, Anastasiades, P G, Lyngholm, D, Vagnoni, C, Rowett, A, Parameswaran, G, Hoerder-Suabedissen, A, Nakagawa, Y, Molnar, Z & Butt, S J B 2021, ' Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal mouse somatosensory cortex ', eLife, vol. 10, e60810 . https://doi.org/10.7554/eLife.60810
eLife

Subplate neurons (SPNs) are thought to play a role in nascent sensory processing in neocortex. To better understand how heterogeneity within this population relates to emergent function, we investigated the synaptic connectivity of Lpar1-EGFP SPNs th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9154a5386b8c29ca242c6975d50eab5
https://elifesciences.org/articles/60810

Non-canonical role for Lpar1-EGFP subplate neurons in early postnatal somatosensory cortex

Autor: Cristiana Vagnoni, Andre Marques-Smith, Yasushi Nakagawa, Paul G. Anastasiades, Filippo Ghezzi, Daniel Lyngholm, Anna Hoerder-Suabedissen, Zoltán Molnár, Alexandra Rowett, Simon J. B. Butt

Subplate neurons (SPNs) are a transient neuronal population shown to play a key role in nascent sensory processing relaying thalamic information to the developing cerebral cortex. However there is little understanding of how heterogeneity within this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a7fdfc908c57e852ba7810f1e5b330
https://doi.org/10.1101/2020.05.12.088450

Functional up-regulation of the M-current by retigabine contrasts hyperexcitability and excitotoxicity on rat hypoglossal motoneurons

Autor: Filippo, Ghezzi, Laura, Monni, Andrea, Nistri

Publikováno v: The Journal of physiology. 596(13)

KEY POINTS: Excessive neuronal excitability characterizes several neuropathological conditions, including neurodegenerative diseases such as amyotrophic lateral sclerosis. Hypoglossal motoneurons (HMs), which control tongue muscles, are extremely vul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2dee7b3e1ef27cf8c0a6c41513d504f4
https://pubmed.ncbi.nlm.nih.gov/29736957