Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Filippo, Favretto"'
Autor:
Marco Pedretti, Carmen Fernández-Rodríguez, Carolina Conter, Iker Oyenarte, Filippo Favretto, Adele di Matteo, Paola Dominici, Maria Petrosino, Maria Luz Martinez-Chantar, Tomas Majtan, Alessandra Astegno, Luis Alfonso Martínez-Cruz
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract The escalating drug resistance among microorganisms underscores the urgent need for innovative therapeutic strategies and a comprehensive understanding of bacteria's defense mechanisms against oxidative stress and antibiotics. Among the rece
Externí odkaz:
https://doaj.org/article/75ffcd6eef8c408387bd5333c21f812c
Autor:
Maria Babu, Filippo Favretto, Alain Ibáñez de Opakua, Marija Rankovic, Stefan Becker, Markus Zweckstetter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
The most frequent cause of familial Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD) are hexanucleotide repeat expansions in the non-coding region of the C9ORF72 gene that are translated into five dipeptide repeat (DPR) proteins.
Externí odkaz:
https://doaj.org/article/5671eab95f98401cbdffa726c9e3c6c6
Autor:
Filippo Favretto, David Flores, Jeremy D. Baker, Timo Strohäker, Loren B. Andreas, Laura J. Blair, Stefan Becker, Markus Zweckstetter
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Cyclophilin A (CypA) is a peptidylprolyl isomerase that also has chaperone activity and interacts with the intrinsically disordered protein α-Synuclein (aSyn). Here, the authors combine NMR measurements and biochemical experiments to characterise th
Externí odkaz:
https://doaj.org/article/f754601d5f914b7aaa2c4a5fef0fc9ba
Autor:
Luca Bombardi, Filippo Favretto, Marco Pedretti, Carolina Conter, Paola Dominici, Alessandra Astegno
Publikováno v:
Biomolecules, Vol 12, Iss 8, p 1115 (2022)
Centrins are calcium (Ca2+)-binding proteins that are involved in many cellular functions including centrosome regulation. A known cellular target of centrins is SFI1, a large centrosomal protein containing multiple repeats that represent centrin-bin
Externí odkaz:
https://doaj.org/article/ad433ce8ec8746a0866e0245e96fd408
Autor:
Carolina Conter, Silvia Fruncillo, Filippo Favretto, Carmen Fernández-Rodríguez, Paola Dominici, Luis Alfonso Martínez-Cruz, Alessandra Astegno
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8169 (2022)
Cystathionine beta-synthase (CBS) is a key regulator of homocysteine metabolism. Although eukaryotic CBS have a similar domain architecture with a catalytic core and a C-terminal Bateman module, their regulation varies widely across phyla. In human C
Externí odkaz:
https://doaj.org/article/f77d48d81f8a496fa39bf118fd894322
Autor:
Marco Pedretti, Luca Bombardi, Carolina Conter, Filippo Favretto, Paola Dominici, Alessandra Astegno
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12173 (2021)
Centrins are a family of small, EF hand-containing proteins that are found in all eukaryotes and are often complexed with centrosome-related structures. Since their discovery, centrins have attracted increasing interest due to their multiple, diverse
Externí odkaz:
https://doaj.org/article/5c6aa7a7013a4aa2bd96311c4d780603
Autor:
Carolina Conter, Filippo Favretto, Paola Dominici, Luis Alfonso Martinez‐Cruz, Alessandra Astegno
Publikováno v:
Proteins: Structure, Function, and Bioinformatics.
Autor:
Carmen Fernández‐Rodríguez, Carolina Conter, Iker Oyenarte, Filippo Favretto, Iban Quintana, Maria Luz Martinez‐Chantar, Alessandra Astegno, Luis Alfonso Martínez‐Cruz
Publikováno v:
Protein Science. 32
Autor:
Filippo Favretto, Eva Jiménez-Faraco, Carolina Conter, Paola Dominici, Juan A. Hermoso, Alessandra Astegno
13 pags., 7 figs., 4 tabs.
Cyclosporin (CsA) has antiparasite activity against the human pathogen Toxoplasma gondii. A possible mechanism of action involves CsA binding to T. gondii cyclophilins, although much remains to be understood. Herein, w
Cyclosporin (CsA) has antiparasite activity against the human pathogen Toxoplasma gondii. A possible mechanism of action involves CsA binding to T. gondii cyclophilins, although much remains to be understood. Herein, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21264cefbc42a207c8d602358b86b089
https://api.elsevier.com/content/abstract/scopus_id/85146563648
https://api.elsevier.com/content/abstract/scopus_id/85146563648
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society 144(35), 16157-16163 (2022). doi:10.1021/jacs.2c07149
Journal of the American Chemical Society 144(35), 16157-16163 (2022). doi:10.1021/jacs.2c07149
Liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) and the action of molecular chaperones are tightly connected. An important class of molecular chaperones are peptidyl prolyl isomerases, which enhance the cis/trans-iso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc7fdb3ccb717826ae5f105bd82041
https://hdl.handle.net/21.11116/0000-000B-7B60-F21.11116/0000-000B-7B62-D
https://hdl.handle.net/21.11116/0000-000B-7B60-F21.11116/0000-000B-7B62-D