Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Filippis, Ioannis"'
Autor:
Cohen, Jeremy, Filippis, Ioannis, Woodbridge, Mark, Bauer, Daniela, Hong, Neil Chue, Jackson, Mike, Butcher, Sarah, Colling, David, Darlington, John, Fuchs, Brian, Harvey, Matt
Publikováno v:
Philosophical Transactions: Mathematical, Physical and Engineering Sciences, 2013 Jan . 371(1983), 1-15.
Externí odkaz:
http://dx.doi.org/10.1098/rsta.2012.0073
Autor:
Cornish, Alex J.1 a.cornish12@imperial.ac.uk, Filippis, Ioannis1, David, Alessia1, Sternberg, Michael J. E.1
Publikováno v:
Genome Medicine. 9/3/2015, Vol. 7 Issue 1, p1-18. 18p.
Publikováno v:
BMC Bioinformatics, Vol 11, Iss 1, p 283 (2010)
Abstract Background Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being preferred by a number of researchers for the description and study of pr
Externí odkaz:
https://doaj.org/article/0385c3cebb5c405ab08a5c0206b38f6b
Publikováno v:
BMC Bioinformatics, Vol 9, Iss 1, p 517 (2008)
Abstract Background Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determining which residues build up an active site is not a straightforw
Externí odkaz:
https://doaj.org/article/cb888824d0e9463ebce062ccfa25c922
Publikováno v:
Journal of Molecular Biology. 426(14):2692-2701
Autor:
Milenković, Tijana1, Filippis, Ioannis2, Lappe, Michael2, Pržulj, Nataša1 natasha@ics.uci.edu
Publikováno v:
PLoS ONE. 2009, Vol. 4 Issue 6, p1-9. 9p. 3 Graphs.
Publikováno v:
Structure(London, England:1993)
Summary The related concepts of protein dynamics, conformational ensembles and allostery are often difficult to study with molecular dynamics (MD) due to the timescales involved. We present ExProSE (Exploration of Protein Structural Ensembles), a dis
Figure S7. Venn diagrams of the diseaseâ cell-type associations (A) supported and (B) not supported by text-mining that are also identified by the GSC and GSO methods. Sets of associations were produced by applying an FDR cutoff of 10 % to the GSC,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662aed794892daffc755298d03e1cf86
Figure S9. Histograms showing the proportions of disease-associated cell types identified by one method supported by another. An FDR cutoff of 10 % was applied to the results of each method to produce sets of diseaseâ cell-type associations. For eac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1491df69c9e276a2f7cc9853f08c9679
Figure S1. Disease-manifesting cell-type-based diseasome. Created by connecting each disease to the two diseases with which it correlates most strongly with respect to the associated cell types. (PDF 951 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5314845be09bda86e2130855e3e6b80e