Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Filipe Tostevin"'
Publikováno v:
Communications Physics, Vol 5, Iss 1, Pp 1-12 (2022)
The total reaction flux catalysed by immobilized enzymes depends on their spatial arrangement. The problem of optimizing the arrangement to maximize the reaction flux is analogous to a portfolio optimization problem, which is solved here to obtain th
Externí odkaz:
https://doaj.org/article/c6807103d4244035a66f31905a7580f9
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008587 (2021)
The mechanisms and design principles of regulatory systems establishing stable polarized protein patterns within cells are well studied. However, cells can also dynamically control their cell polarity. Here, we ask how an upstream signaling system ca
Externí odkaz:
https://doaj.org/article/025ba98141d047f28cf213c730e50a42
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008877 (2020)
Cell polarity underlies key processes in all cells, including growth, differentiation and division. In the bacterium Myxococcus xanthus, front-rear polarity is crucial for motility. Notably, this polarity can be inverted, independent of the cell-cycl
Externí odkaz:
https://doaj.org/article/8774a729fc0342aba150cd515fffd6d4
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 213-221 (2016)
Cells have evolved diverse mechanisms that maintain intracellular homeostasis in fluctuating environments. In bacteria, control is often exerted by bifunctional receptors acting as both kinase and phosphatase to regulate gene expression, a design kno
Externí odkaz:
https://doaj.org/article/f8d767c6976146c28eafa3446e5061c8
Autor:
Sarah Boulineau, Filipe Tostevin, Daniel J Kiviet, Pieter Rein ten Wolde, Philippe Nghe, Sander J Tans
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61686 (2013)
Stochasticity in gene regulation has been characterized extensively, but how it affects cellular growth and fitness is less clear. We study the growth of E. coli cells as they shift from glucose to lactose metabolism, which is characterized by an obl
Externí odkaz:
https://doaj.org/article/672c1afe9926453293d6975e741587ba
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 4, p e78 (2007)
Position determination in biological systems is often achieved through protein concentration gradients. Measuring the local concentration of such a protein with a spatially varying distribution allows the measurement of position within the system. Fo
Externí odkaz:
https://doaj.org/article/3ff137bb2de84532bfddd97ba65f1bba
Publikováno v:
Nature Physics. 18:203-211
Spatial organization of catalytic particles is ubiquitous in biological systems across different length scales, from enzyme complexes to metabolically coupled cells. Despite the different scales, these systems share common features of localized react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517c8f62efe816d877dec93cc94d69f2
https://doi.org/10.1038/s41567-021-01444-4
https://doi.org/10.1038/s41567-021-01444-4
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008587 (2021)
PLoS Computational Biology
PLoS Computational Biology
The mechanisms and design principles of regulatory systems establishing stable polarized protein patterns within cells are well studied. However, cells can also dynamically control their cell polarity. Here, we ask how an upstream signaling system ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb1b2a92ef402fb23e9d91463864b0e0
https://doaj.org/article/025ba98141d047f28cf213c730e50a42
https://doaj.org/article/025ba98141d047f28cf213c730e50a42
Publikováno v:
Biophysical Journal
Intracellular compartmentalization of cooperating enzymes is a strategy that is frequently used by cells. Segregation of enzymes that catalyze sequential reactions can alleviate challenges such as toxic pathway intermediates, competing metabolic reac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd71711dfebb830c75083d388a7f34a
http://europepmc.org/articles/PMC5340097
http://europepmc.org/articles/PMC5340097
Publikováno v:
Cell Reports, Vol 16, Iss 1, Pp 213-221 (2016)
SummaryCells have evolved diverse mechanisms that maintain intracellular homeostasis in fluctuating environments. In bacteria, control is often exerted by bifunctional receptors acting as both kinase and phosphatase to regulate gene expression, a des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c2ea8bce90a0dd71f4b8b788e96f42
http://www.sciencedirect.com/science/article/pii/S2211124716306945
http://www.sciencedirect.com/science/article/pii/S2211124716306945