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Multiomics atlas-assisted discovery of transcription factors enables specific cell state programming
Autor:
H. Kay Chung, Cong Liu, Eduardo Casillas, Brent Chick, Bryan Mcdonald, Jun Wang, Peixiang He, Ming Sun, Shixin Ma, Qiyuan Yang, Dan Chen, Filipe Hoffmann, Siva Karthik Varanasi, Victoria Tripple, Yuqing Hang, Ukrae H. Cho, Josephine Ho, April Williams, Yingxiao Wang, Diana Hargreaves, Susan M. Kaech, Wei Wang
Publikováno v:
bioRxiv
The same types of cells can assume diverse states with varying functionalities. Effective cell therapy can be achieved by specifically driving a desirable cell state, which requires the elucidation of key transcription factors (TFs). Here, we integra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa410dfe3083f8823ac951d14b75dd94
https://doi.org/10.1101/2023.01.03.522354
https://doi.org/10.1101/2023.01.03.522354