Identification and Characterization of miRNA regulatory networks

Autor: Filipchyk, Andrei

Post-transkriptionelle Genregulation ist ein zentraler Mechanismus, den lebende Organismen nutzen, um Funktionalität, Entwicklung und Anpassung zu gewährleisten. Defizite in diesem Mechanismus haben zahlreiche Krankheiten und Fehlfunktionen zur Fol

Externí odkaz: http://edoc.hu-berlin.de/18452/21305

HrrSA orchestrates a systemic response to heme and determines prioritization of terminal cytochrome oxidase expression

Autor: Keppel, Marc, Hünnefeld, Max, Filipchyk, Andrei, Viets, Ulrike, Davoudi, Cedric-Farhad, Krüger, Aileen, Mack, Christina, Pfeifer, Eugen, Polen, Tino, Baumgart, Meike, Bott, Michael, Frunzke, Julia

Publikováno v: Nucleic Acids Research
Nucleic acids research 48(12), 6547-6562 (2020). doi:10.1093/nar/gkaa415

Heme is a multifaceted molecule. While serving as a prosthetic group for many important proteins, elevated levels are toxic to cells. The complexity of this stimulus has shaped bacterial network evolution. However, only a small number of targets cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::82ce7323b5da69ddaeda9dff1bd9bce4
http://europepmc.org/articles/PMC7337898

Deciphering the Rules Underlying Xenogeneic Silencing and Counter-Silencing of Lsr2-like Proteins Using CgpS of Corynebacterium glutamicum as a Model

Autor: Wiechert, Johanna, Filipchyk, Andrei, Hünnefeld, Max, Gätgens, Cornelia, Brehm, Jannis, Heermann, Ralf, Frunzke, Julia

Publikováno v: mBio, Vol 11, Iss 1, p e02273-19 (2020)
mBio 11(1), e02273-19/mbio/11/1/mBio.02273-19.atom (2020). doi:10.1128/mBio.02273-19
mBio, Vol 11, Iss 1 (2020)
mBio

In actinobacteria, Lsr2-like nucleoid-associated proteins function as xenogeneic silencers (XS) of horizontally acquired genomic regions, including viral elements, virulence gene clusters in Mycobacterium tuberculosis, and genes involved in cryptic s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::4e82fc38a1861b074a9b60e7dc21ddec
https://doaj.org/article/d7f7c3ae09644c0ea3c1f96caa6c2f9f

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