Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Filipa I Baptista"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65515 (2013)
Diabetes mellitus is the most common metabolic disorder in humans. Diabetic encephalopathy is characterized by cognitive and memory impairments, which have been associated with changes in the hippocampus, but the mechanisms underlying those impairmen
Externí odkaz:
https://doaj.org/article/395a8bdc44114f0098029ba7279222dd
Autor:
Áurea F Castilho, Célia A Aveleira, Ermelindo C Leal, Núria F Simões, Carolina R Fernandes, Rita I Meirinhos, Filipa I Baptista, António F Ambrósio
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42428 (2012)
Diabetic retinopathy is a leading cause of visual loss and blindness, characterized by microvascular dysfunction. Hyperglycemia is considered the major pathogenic factor for the development of diabetic retinopathy and is associated with increased oxi
Externí odkaz:
https://doaj.org/article/a4ee5ee8c61841438004079329e44f92
Autor:
Renato Socodato, Tiago O. Almeida, Camila C. Portugal, Evelyn C.S. Santos, Joana Tedim-Moreira, João Galvão-Ferreira, Teresa Canedo, Filipa I. Baptista, Ana Magalhães, António F. Ambrósio, Cord Brakebusch, Boris Rubinstein, Irina S. Moreira, Teresa Summavielle, Inês Mendes Pinto, João B. Relvas
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113447- (2023)
Summary: Microglia, the largest population of brain immune cells, continuously interact with synapses to maintain brain homeostasis. In this study, we use conditional cell-specific gene targeting in mice with multi-omics approaches and demonstrate th
Externí odkaz:
https://doaj.org/article/914f35ba494042d8aa265dd02cbdf0a4
Autor:
Carla Filipa Simões-Henriques, A. Catarina Rodrigues-Neves, Fábio J. Sousa, Rita Gaspar, Inês Almeida, Filipa I. Baptista, António F. Ambrósio, Catarina A. Gomes
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
The involvement of immunity in psychiatric disorders, such as anxiety, is typified by the morphologic adaptation of microglia, immune cells of the brain, to anxiogenic stimuli. We previously reported sexually differentiated microglia morphology in ad
Externí odkaz:
https://doaj.org/article/687e04dfefae464797f0beeea699c0fa
Autor:
Rita Gaspar, Carina Soares-Cunha, Ana Verónica Domingues, Bárbara Coimbra, Filipa I. Baptista, Luísa Pinto, António F. Ambrósio, Ana João Rodrigues, Catarina A. Gomes
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Stress exposure has been shown to induce a variety of molecular and functional alterations associated with anxiety and depression. Some studies suggest that microglia, the immune cells of the brain, play a significant role in determining neuronal and
Externí odkaz:
https://doaj.org/article/75dba4dd43fc4e86ab13b2ea9edd5f81
Autor:
Rita Gaspar, Carina Soares-Cunha, Ana Verónica Domingues, Bárbara Coimbra, Filipa I. Baptista, Luísa Pinto, António F. Ambrósio, Ana João Rodrigues, Catarina A. Gomes
Publikováno v:
Neurobiology of Stress, Vol 14, Iss , Pp 100302- (2021)
Prenatal exposure to stress or glucocorticoids (GC) is associated with the appearance of psychiatric diseases later in life. Microglia, the immune cells of the brain, are altered in stress-related disorders.Synthetic GC such as dexamethasone (DEX) ar
Externí odkaz:
https://doaj.org/article/c7022f8cf5f842d49fe2e113aea12556
Autor:
Fábio J. Sousa, Raquel G. Correia, Alexandra F. Cruz, Joana M. Martins, Matilde S. Rodrigues, Catarina A. Gomes, António F. Ambrósio, Filipa I. Baptista
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 5, Iss , Pp 100075- (2020)
Diabetes during pregnancy has been shown to affect the central nervous system (CNS) of the offspring, resulting in short- and long-term adverse effects. Children of diabetic mothers are more likely to develop cognitive impairment, also having increas
Externí odkaz:
https://doaj.org/article/78380c8113c046a3bbd7354c49562554
Publikováno v:
Mediators of Inflammation, Vol 2017 (2017)
Diabetic retinopathy is considered a neurovascular disorder, hyperglycemia being considered the main risk factor for this pathology. Diabetic retinopathy also presents features of a low-grade chronic inflammatory disease, including increased levels o
Externí odkaz:
https://doaj.org/article/4e0b20c5cb69425798ba261241d0ff27
Autor:
Andreia Amaro, Diana Sousa, Mariana Sá-Rocha, Marcos D. Ferreira-Junior, Cátia Barra, Tamaeh Monteiro, Paulo Mathias, Rodrigo Mello Gomes, Filipa I. Baptista, Paulo Matafome
Publikováno v:
Life Sciences. 321:121597
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27429087a27e40f7b519b60a5ce9d760
https://doi.org/10.1016/j.lfs.2023.121597
https://doi.org/10.1016/j.lfs.2023.121597
Autor:
Bárbara S. Pinheiro, Liane I.F. Moura, António F. Ambrósio, Isaura Tavares, Eugenia Carvalho, João M. N. Duarte, Samira G. Ferreira, Cristina Lemos, Attila Köfalvi, Fernanda Neutzling Kaufmann, Ângela Valério-Fernandes, Rodrigo A. Cunha, Filipa I. Baptista, C. Morgado, Joana R. Pedro, Carla S. da Silva-Santos, Joana M. Gaspar
Publikováno v:
Brain Res Bull
Here we aimed to unify some previous controversial reports on changes in both cannabinoid CB(1) receptor (CB(1)R) expression and glucose metabolism in the forebrain of rodent models of diabetes. We determined how glucose metabolism and its modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcdb4b9e8523e13d52d5cb4d4eb02d40
https://doi.org/10.1016/j.brainresbull.2020.05.004
https://doi.org/10.1016/j.brainresbull.2020.05.004