Design, synthesis, and biological activity of D-bishomo-1α,25-dihydroxyvitamin D 3 analogs and their crystal structures with the vitamin D nuclear receptor.

Autor: Fabisiak A; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland. Electronic address: afabisiak@chem.uw.edu.pl., Brzeminski P; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland., Sicinski RR; Department of Chemistry, University of Warsaw, Pasteura 1, 02-093, Warsaw, Poland., Rochel N; Department of Integrative Structural Biology, IGBMC - Université de Strasbourg, CNRS UMR 7104, INSERM U1258, 67400, Illkirch, France., Maj E; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Filip-Psurska B; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Wietrzyk J; Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Rudolf Weigl Street, 53-114, Wrocław, Poland., Plum LA; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA., DeLuca HF; Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI, 53706, USA.

Publikováno v: European journal of medicinal chemistry [Eur J Med Chem] 2024 May 05; Vol. 271, pp. 116403. Date of Electronic Publication: 2024 Apr 10.

Prenylated Flavonoids with Selective Toxicity against Human Cancers.

Autor: Tronina T; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland., Bartmańska A; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland., Popłoński J; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland., Rychlicka M; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland., Sordon S; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland., Filip-Psurska B; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114 Wroclaw, Poland., Milczarek M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114 Wroclaw, Poland., Wietrzyk J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Weigla 12, 53-114 Wroclaw, Poland., Huszcza E; Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, C.K. Norwida 25, 50-375 Wrocław, Poland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Apr 18; Vol. 24 (8). Date of Electronic Publication: 2023 Apr 18.

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Combined anticancer therapy with imidazoacridinone analogue C-1305 and paclitaxel in human lung and colon cancer xenografts-Modulation of tumour angiogenesis.

Autor: Świtalska M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Wrocław, Poland., Filip-Psurska B; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Wrocław, Poland., Milczarek M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Wrocław, Poland., Psurski M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Wrocław, Poland., Moszyńska A; Department of Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdańsk, Poland.; Department of Immunology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland., Dąbrowska AM; Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland., Gawrońska M; Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland., Krzymiński K; Faculty of Chemistry, University of Gdańsk, Gdańsk, Poland., Bagiński M; Department of Pharmaceutical Technology and Biochemistry, Faculty of Chemistry, Gdansk University of Technology, Gdańsk, Poland., Bartoszewski R; Department of Biology and Pharmaceutical Botany, Medical University of Gdansk, Gdańsk, Poland., Wietrzyk J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Wrocław, Poland.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2022 Jul; Vol. 26 (14), pp. 3950-3964. Date of Electronic Publication: 2022 Jun 14.

Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models.

Autor: Filip-Psurska B; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Psurski M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Anisiewicz A; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Libako P; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Zbrojewicz E; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Maciejewska M; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland., Chodyński M; Łukasiewicz Research Network-Industrial Chemistry Institute, 8 Rydygiera, 01-793 Warsaw, Poland., Kutner A; Department of Bioanalysis and Drug Analysis, Faculty of Pharmacy, Medical University of Warsaw, 1 Banacha, 02-097 Warsaw, Poland., Wietrzyk J; Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, 12 Weigl, 53-114 Wroclaw, Poland.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Mar 09; Vol. 22 (5). Date of Electronic Publication: 2021 Mar 09.