Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Filip Zmuda"'
Autor:
Carolina Locatelli, Filip Zmuda, Christine Salaün, Juan Cabrera González, Luke H. Chamberlain
Almost two decades have passed since seminal work in Saccharomyces cerevisiae identified zinc finger DHHC domain-containing (zDHHC) enzymes as S-acyltransferases. These enzymes are ubiquitous in the eukarya domain, with 23 distinct zDHHC-encoding gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a95cae3a6afae2b58dedb61c14a048cf
https://strathprints.strath.ac.uk/73926/1/Salaun_etal_JCS_2020_Accessory_proteins_of_the_zDHHC_family_of_S_acylation.pdf
https://strathprints.strath.ac.uk/73926/1/Salaun_etal_JCS_2020_Accessory_proteins_of_the_zDHHC_family_of_S_acylation.pdf
Autor:
Filip Zmuda, Luke H. Chamberlain
The human zDHHC S-acyltransferase family comprises 23 enzymes that mediate the S-acylation of a multitude of cellular proteins, including channels, receptors, transporters, signaling molecules, scaffolds, and chaperones. This reversible post-transiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c310e5f63bce0f7b22264a3d1e5141f8
https://strathprints.strath.ac.uk/73637/7/Zmuda_Chamberlain_JBC_2020_Regulatory_effects_of_post_translational_modifications_on_zDHHC_S_acyltransferases.pdf
https://strathprints.strath.ac.uk/73637/7/Zmuda_Chamberlain_JBC_2020_Regulatory_effects_of_post_translational_modifications_on_zDHHC_S_acyltransferases.pdf
Autor:
Maria Clara Liuzzi, Adele Blair, Anthony J. Chalmers, Sally L. Pimlott, Andrew Sutherland, Filip Zmuda, Gaurav Malviya, David Y. Lewis
Publikováno v:
Journal of Medicinal Chemistry. 61:4103-4114
Poly(ADP-ribose) polymerase (PARP) is involved in repair of DNA breaks and is over-expressed in a wide variety of tumors, making PARP an attractive biomarker for positron emission tomography (PET) and single photon emission computed tomography imagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9161e2b78ff68cbc6467a4b62a94793a
https://doi.org/10.1021/acs.jmedchem.8b00138
https://doi.org/10.1021/acs.jmedchem.8b00138
Autor:
Sharon M. Shepherd, Filip Zmuda, Michael A. J. Ferguson, Manu De Rycker, David W. Gray, Leah S. Torrie
Publikováno v:
Antimicrobial Agents and Chemotherapy
Chagas’ disease, which is caused by the Trypanosoma cruzi parasite, has become a global health problem that is currently treated with poorly tolerated drugs that require prolonged dosing. Therefore, there is a clinical need for new therapeutic agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233a038dace5079b1d8036c5c1d54cc3
https://doi.org/10.1128/aac.01082-19
https://doi.org/10.1128/aac.01082-19
Autor:
Filip, Zmuda, Lalitha, Sastry, Sharon M, Shepherd, Deuan, Jones, Alison, Scott, Peter D, Craggs, Alvaro, Cortes, David W, Gray, Leah S, Torrie, Manu, De Rycker
Publikováno v:
Antimicrobial Agents and Chemotherapy
Chagas’ disease, caused by the protozoan parasite Trypanosoma cruzi, is a potentially life-threatening condition that has become a global issue. Current treatment is limited to two medicines that require prolonged dosing and are associated with mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ad05f3ce13b5bcab8deb901904fe4ffe
https://pubmed.ncbi.nlm.nih.gov/31307977
https://pubmed.ncbi.nlm.nih.gov/31307977
Autor:
Filip, Zmuda, Adele, Blair, Maria Clara, Liuzzi, Gaurav, Malviya, Anthony J, Chalmers, David, Lewis, Andrew, Sutherland, Sally L, Pimlott
Publikováno v:
Journal of medicinal chemistry. 61(9)
Poly(ADP-ribose) polymerase (PARP) is involved in repair of DNA breaks and is over-expressed in a wide variety of tumors, making PARP an attractive biomarker for positron emission tomography (PET) and single photon emission computed tomography imagin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ed5df871aedca18b186a0834fc4f9c2
https://pubmed.ncbi.nlm.nih.gov/29630818
https://pubmed.ncbi.nlm.nih.gov/29630818
Autor:
Andrew Sutherland, Gilles Tamagnan, Filip Zmuda, Adriana Tavares, Anthony J. Chalmers, Deborah Dewar, Adele Blair, Sally L. Pimlott, Gaurav Malviya
Publikováno v:
Chemical Science. 6:4772-4777
The translocator protein (TSPO) is an important target for imaging focal neuroinflammation in diseases such as brain cancer, stroke and neurodegeneration, but current tracers for non-invasive imaging of TSPO have important limitations. We present the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7874dd2c621c84505299712078f50e0a
https://doi.org/10.1039/c5sc01647a
https://doi.org/10.1039/c5sc01647a
Autor:
Marie Boyd, Anthony J. Chalmers, Andrew Sutherland, Adele Blair, Filip Zmuda, Sally L. Pimlott, Gaurav Malviya
Interest in nuclear imaging of poly(ADP-ribose) polymerase-1 (PARP-1) has grown in recent years due to the ability of PARP-1 to act as a biomarker for glioblastoma and increased clinical use of PARP-1 inhibitors. This study reports the identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10b4f2e9c630f57ec36d28f8aea9362
https://strathprints.strath.ac.uk/55139/1/Zmuda_etal_JMC_2015_Synthesis_and_evaluation_of_a_radioiodinated_tracer_with_specificity.pdf
https://strathprints.strath.ac.uk/55139/1/Zmuda_etal_JMC_2015_Synthesis_and_evaluation_of_a_radioiodinated_tracer_with_specificity.pdf
Autor:
Filip Zmuda, Gaurav Malviya, Adele Blair, Marie Boyd, AnthonyJ. Chalmers, Andrew Sutherland, Sally L. Pimlott
Publikováno v:
Journal of Medicinal Chemistry; Nov2015, Vol. 58 Issue 21, p8683-8693, 11p