Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Filip Stefaniak"'
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 6, p e1009783 (2022)
Computational methods play a pivotal role in drug discovery and are widely applied in virtual screening, structure optimization, and compound activity profiling. Over the last decades, almost all the attention in medicinal chemistry has been directed
Externí odkaz:
https://doaj.org/article/6cbd49b2c37344c7a5bbee1e99d33373
Autor:
Mariola Stypik, Marcin Zagozda, Stanisław Michałek, Barbara Dymek, Daria Zdżalik-Bielecka, Maciej Dziachan, Nina Orłowska, Paweł Gunerka, Paweł Turowski, Joanna Hucz-Kalitowska, Aleksandra Stańczak, Paulina Stańczak, Krzysztof Mulewski, Damian Smuga, Filip Stefaniak, Lidia Gurba-Bryśkiewicz, Arkadiusz Leniak, Zbigniew Ochal, Mateusz Mach, Karolina Dzwonek, Monika Lamparska-Przybysz, Krzysztof Dubiel, Maciej Wieczorek
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 949 (2022)
Phosphoinositide 3-kinase δ (PI3Kδ), a member of the class I PI3K family, is an essential signaling biomolecule that regulates the differentiation, proliferation, migration, and survival of immune cells. The overactivity of this protein causes cell
Externí odkaz:
https://doaj.org/article/4dd8c9f6c70e4b8898c041fd13130a7c
Autor:
Filip Stefaniak, Janusz M Bujnicki
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008309 (2021)
RNA is considered as an attractive target for new small molecule drugs. Designing active compounds can be facilitated by computational modeling. Most of the available tools developed for these prediction purposes, such as molecular docking or scoring
Externí odkaz:
https://doaj.org/article/f2fcf9bfc31b45078288850de40830cb
Ribonucleic acids (RNA) play crucial roles in living organisms as they are involved in key processes necessary for proper cell functioning. Some RNA molecules, such as bacterial ribosomes and precursor messenger RNA, are targets of small molecule dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06633725ec57c0fe545091b5cfaf7afd
https://doi.org/10.1101/2023.01.11.523582
https://doi.org/10.1101/2023.01.11.523582
Autor:
Astha Joshi, Chandran Nithin, Janusz M. Bujnicki, Tomasz K Wirecki, Filip Stefaniak, Pritha Ghosh
Publikováno v:
Ribozymes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3323ebbb9d128fbacfa053a36aedf5af
https://doi.org/10.1002/9783527814527.ch33
https://doi.org/10.1002/9783527814527.ch33
Autor:
Filip Stefaniak, Janusz M. Bujnicki, Tomasz K Wirecki, Katarzyna Merdas, Agata Bernat, Michal J. Boniecki
Publikováno v:
Nucleic Acids Research
RNA molecules play key roles in all living cells. Knowledge of the structural characteristics of RNA molecules allows for a better understanding of the mechanisms of their action. RNA chemical probing allows us to study the susceptibility of nucleoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::045952eda2ae0610a426e661fa2c5abe
https://doi.org/10.1093/nar/gkaa396
https://doi.org/10.1093/nar/gkaa396
Computational methods play a pivotal role in drug discovery and are widely applied in virtual screening, structure optimization, and compound activity profiling. Over the last decades, almost all the attention in medicinal chemistry has been directed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::959e51e00d9ebdb9568f8df3a0a5e109
https://doi.org/10.1101/2021.12.23.474073
https://doi.org/10.1101/2021.12.23.474073
Publikováno v:
PLoS computational biology. 18(6)
Computational methods play a pivotal role in drug discovery and are widely applied in virtual screening, structure optimization, and compound activity profiling. Over the last decades, almost all the attention in medicinal chemistry has been directed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e4a41028389d5f6da2a25c0bd60632
https://pubmed.ncbi.nlm.nih.gov/35653385
https://pubmed.ncbi.nlm.nih.gov/35653385
Autor:
Pietro Boccaletto, Filip Stefaniak, Angana Ray, Andrea Cappannini, Sunandan Mukherjee, Elżbieta Purta, Małgorzata Kurkowska, Niloofar Shirvanizadeh, Eliana Destefanis, Paula Groza, Gülben Avşar, Antonia Romitelli, Pınar Pir, Erik Dassi, Silvestro G Conticello, Francesca Aguilo, Janusz M Bujnicki
Publikováno v:
Nucleic Acids Research
The MODOMICS database has been, since 2006, a manually curated and centralized resource, storing and distributing comprehensive information about modified ribonucleosides. Originally, it only contained data on the chemical structures of modified ribo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f95af47d3f452b2382f3d2f0ef51c4
https://pubmed.ncbi.nlm.nih.gov/34893873
https://pubmed.ncbi.nlm.nih.gov/34893873
Autor:
Filip Stefaniak, Janusz M. Bujnicki
RNA is considered as an attractive target for new small molecule drugs. Designing active compounds can be facilitated by computational modeling. Most of the available tools developed for these prediction purposes, such as molecular docking or scoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecbdf7aa1fffafd3a52487618fa3ec2
https://doi.org/10.1101/2020.09.08.287136
https://doi.org/10.1101/2020.09.08.287136