Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Filip S. Ekholm"'
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Surachet Imlimthan, Olli Aitio, Mirkka Sarparanta, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecules, Vol 29, Iss 17, p 4263 (2024)
Boron Neutron Capture Therapy (BNCT) is a cancer treatment which combines tumor-selective boron delivery agents with thermal neutrons in order to selectively eradicate cancer cells. In this work, we focus on the early-stage development of carbohydrat
Externí odkaz:
https://doaj.org/article/9c47b19bd5b341ce9b2e8aff4ce2ab60
Autor:
Jelena Matović, Katayun Bahrami, Philipp Stockmann, Iris K. Sokka, You Cheng Khng, Mirkka Sarparanta, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Publikováno v:
Molecular Pharmaceutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c1e4a225677d7dd5243d38b06858293
https://doi.org/10.1021/acs.molpharmaceut.3c00119
https://doi.org/10.1021/acs.molpharmaceut.3c00119
Publikováno v:
Nano Letters. 21:7676-7683
In healthy eyes, the tear film lipid layer (TFLL) is considered to act as an evaporation resistant barrier, which prevents eyes from drying. Seeking to understand the mechanisms behind the evaporation resistance of the TFLL, we studied mixtures of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6b3d28ccff1d1ca4a0965da9e2ad1f
https://doi.org/10.1021/acs.nanolett.1c02475
https://doi.org/10.1021/acs.nanolett.1c02475
Autor:
Mirkka Sarparanta, Surachet Imlimthan, Iris Katariina Sokka, Filip S. Ekholm, Mikael P. Johansson, Hannu Maaheimo
Publikováno v:
Sokka, I K, Imlimthan, S, Sarparanta, M, Maaheimo, H, Johansson, M P & Ekholm, F S 2021, ' Halogenation at the phenylalanine residue of monomethyl auristatin f leads to a favorable cis/ trans equilibrium and retained cytotoxicity ', Molecular Pharmaceutics, vol. 18, no. 8, pp. 3125-3131 . https://doi.org/10.1021/acs.molpharmaceut.1c00342
Molecular Pharmaceutics
Molecular Pharmaceutics
Halogenation can be utilized for the purposes of labeling and molecular imaging, providing a means to, e.g., follow drug distribution in an organism through positron emission tomography (PET) or study the molecular recognition events unfolding by nuc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d95f58ef077c9074a6334b247722d50d
https://doi.org/10.1021/acs.molpharmaceut.1c00342
https://doi.org/10.1021/acs.molpharmaceut.1c00342
Autor:
Jelena Matović, Juulia Järvinen, Iris K. Sokka, Philipp Stockmann, Martin Kellert, Surachet Imlimthan, Mirkka Sarparanta, Mikael P. Johansson, Evamarie Hey-Hawkins, Jarkko Rautio, Filip S. Ekholm
Glucose-and sodium-dependent glucose transporters (GLUTs and SGLTs) play vital roles in human biology. Of the 14 GLUTs and 12 SGLTs, the GLUT1 transporter has gained t h e most widespread recognition because GLUT1 is overexpressed in several cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f817c06505986eb7aff16321321477a
http://hdl.handle.net/10138/350550
http://hdl.handle.net/10138/350550
Autor:
Jelena, Matović, Juulia, Järvinen, Iris K, Sokka, Philipp, Stockmann, Martin, Kellert, Surachet, Imlimthan, Mirkka, Sarparanta, Mikael P, Johansson, Evamarie, Hey-Hawkins, Jarkko, Rautio, Filip S, Ekholm
Publikováno v:
ACS omega. 7(34)
Glucose- and sodium-dependent glucose transporters (GLUTs and SGLTs) play vital roles in human biology. Of the 14 GLUTs and 12 SGLTs, the GLUT1 transporter has gained the most widespread recognition because GLUT1 is overexpressed in several cancers a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::605ee06346d03ebe3fa17fea2d7cda23
https://pubmed.ncbi.nlm.nih.gov/36061667
https://pubmed.ncbi.nlm.nih.gov/36061667
Publikováno v:
The Journal of Organic Chemistry
Correction: 10.1021/acs.joc.1c02513. The tear film lipid layer (TFLL) that covers the ocular surface contains several unique lipid classes, including O-acyl-omega-hydroxy fatty acids, type I-St diesters, and type II diesters. While the TFLL represent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e265d836c9688fa36676742e13ba96
http://europepmc.org/articles/PMC8041317
http://europepmc.org/articles/PMC8041317
Autor:
Filip S. Ekholm, Suvi-Katriina Ruokonen, Marina Redón, Virve Pitkänen, Anja Vilkman, Juhani Saarinen, Jari Helin, Tero Satomaa, Susanne K. Wiedmer
Publikováno v:
Separations, Vol 6, Iss 1, p 1 (2018)
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. The idea behind the ADC technology is remarkable as it combines the highly s
Externí odkaz:
https://doaj.org/article/ce3bcce3ae8246aabae69be02a0c9af4
Publikováno v:
Nano letters. 21(18)
In healthy eyes, the tear film lipid layer (TFLL) is considered to act as an evaporation resistant barrier, which prevents eyes from drying. Seeking to understand the mechanisms behind the evaporation resistance of the TFLL, we studied mixtures of li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1d9a210f1d6cdee6d561370223e7f0be
https://pubmed.ncbi.nlm.nih.gov/34468151
https://pubmed.ncbi.nlm.nih.gov/34468151
Publikováno v:
Molecular Pharmaceutics
Monomethyl auristatin E and monomethyl auristatin F are widely used cytotoxic agents in antibody-drug conjugates (ADCs), a group of promising cancer drugs. The ADCs specifically target cancer cells, releasing the auristatins inside, which results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba6c51077c520f186b105cbb2e8a6fc
http://europepmc.org/articles/PMC6750905
http://europepmc.org/articles/PMC6750905