Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Filip Rob"'
Autor:
Eliška Vrbová, Petra Pospíšilová, Eliška Dastychová, Martina Kojanová, Miluše Kreidlová, Filip Rob, Vladimír Vašků, Petra Mosio, Radim Strnadel, Olga Faustmannová, Ivana Kuklová, Monika Dvořáková Heroldová, Hana Zákoucká, David Šmajs
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Syphilis is a multistage sexually transmitted disease caused by Treponema pallidum ssp. pallidum. In the Czech Republic, there are around 700–800 new syphilis cases annually, continuously increasing since 2012. This study analyzed a total
Externí odkaz:
https://doaj.org/article/c8c1e6bafa9d43f88d53fde3fcd7ca18
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 4, Pp 911-933 (2023)
Abstract Psoriasis is a chronic, immune-mediated, inflammatory disease primarily affecting the skin. It is currently coming to light that patients with psoriasis have disrupted intestinal barrier and often suffer from comorbidities associated with th
Externí odkaz:
https://doaj.org/article/e05767250ae347ecbdf597448f9ac1a2
Autor:
Stepan Coufal, Miloslav Kverka, Jakub Kreisinger, Tomas Thon, Filip Rob, Martin Kolar, Zuzana Reiss, Dagmar Schierova, Klara Kostovcikova, Radka Roubalova, Lukas Bajer, Zuzana Jackova, Martin Mihula, Pavel Drastich, Jana Tresnak Hercogova, Michaela Novakova, Martin Vasatko, Milan Lukas, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Background. Tumor necrosis factor-alpha (TNF-α) agonists revolutionized therapeutic algorithms in inflammatory bowel disease (IBD) management. However, approximately every third IBD patient does not respond to this therapy in the long term, which de
Externí odkaz:
https://doaj.org/article/65bf846ae46d4d019cc3d1fd3e4f4af7
Autor:
Zuzana Reiss, Filip Rob, Martin Kolar, Dagmar Schierova, Jakub Kreisinger, Zuzana Jackova, Radka Roubalova, Stepan Coufal, Martin Mihula, Tomas Thon, Lukas Bajer, Michaela Novakova, Martin Vasatko, Klara Kostovcikova, Natalie Galanova, Milan Lukas, Miloslav Kverka, Jana Tresnak Hercogova, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2023)
Crohn’s disease (CD) and ulcerative colitis (UC) are two forms of inflammatory bowel disease (IBD), where the role of gut but not skin dysbiosis is well recognized. Inhibitors of TNF have been successful in IBD treatment, but up to a quarter of pat
Externí odkaz:
https://doaj.org/article/5f297a06b11e4563ad6ccd1dbdc90bc1
Autor:
Filip Rob, Dagmar Schierova, Zuzana Stehlikova, Jakub Kreisinger, Radka Roubalova, Stepan Coufal, Martin Mihula, Zuzana Jackova, Miloslav Kverka, Tomas Thon, Klara Kostovcikova, Lukas Bajer, Pavel Drastich, Jana Tresnak Hercogova, Michaela Novakova, Martin Kolar, Martin Vasatko, Milan Lukas, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
PLoS ONE, Vol 17, Iss 12, p e0277576 (2022)
BackgroundUstekinumab, is a new therapy for patients with IBD, especially for patients suffering from Crohn's disease (CD) who did not respond to anti-TNF treatment. To shed light on the longitudinal effect of ustekinumab on the immune system, we inv
Externí odkaz:
https://doaj.org/article/1ce2e1563132443fabce1df4c3d02de5
Autor:
Eliška Vrbová, Lenka Mikalová, Linda Grillová, Petra Pospíšilová, Radim Strnadel, Eliška Dastychová, Martina Kojanová, Miluše Kreidlová, Daniela Vaňousová, Filip Rob, Přemysl Procházka, Alena Krchňáková, Vladimír Vašků, Vladana Woznicová, Monika Dvořáková Heroldová, Ivana Kuklová, Hana Zákoucká, David Šmajs
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237949 (2020)
Syphilis, caused by Treponema pallidum ssp. pallidum (TPA), is a persisting global health problem. Although syphilis diagnostics relies mainly on serology, serological tests have some limitations, and it is recommended that the final diagnosis be sup
Externí odkaz:
https://doaj.org/article/4403746872854f47a2614131705e1ce7
Autor:
Dagmar Schierova, Radka Roubalova, Martin Kolar, Zuzana Stehlikova, Filip Rob, Zuzana Jackova, Stepan Coufal, Tomas Thon, Martin Mihula, Martin Modrak, Miloslav Kverka, Lukas Bajer, Klara Kostovcikova, Pavel Drastich, Jana Hercogova, Michaela Novakova, Martin Vasatko, Milan Lukas, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
Cells, Vol 10, Iss 11, p 3188 (2021)
Inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract that have been linked to microbiome dysbiosis and immune system dysregulation. We investigated the longitudinal effect of anti-TNF therapy on gut microbiota composi
Externí odkaz:
https://doaj.org/article/8eaa98d5e195490994072169e9a9f0b2
Autor:
Zuzana Stehlikova, Martin Kostovcik, Klara Kostovcikova, Miloslav Kverka, Katerina Juzlova, Filip Rob, Jana Hercogova, Petr Bohac, Yishay Pinto, Atara Uzan, Omry Koren, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Psoriasis is a chronic inflammatory skin disease, whose pathogenesis involves dysregulated interplay among immune cells, keratinocytes and environmental triggers, including microbiota. Bacterial and fungal dysbiosis has been recently associated with
Externí odkaz:
https://doaj.org/article/75fefc762c53465eafaaacbbf130bc6e
Autor:
Zuzana Stehlikova, Klara Kostovcikova, Miloslav Kverka, Pavel Rossmann, Jiri Dvorak, Iva Novosadova, Martin Kostovcik, Stepan Coufal, Dagmar Srutkova, Petra Prochazkova, Tomas Hudcovic, Hana Kozakova, Renata Stepankova, Filip Rob, Katerina Juzlova, Jana Hercogova, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Psoriatic patients have altered microbiota, both in the intestine and on the skin. It is not clear, however, whether this is a cause or consequence of the disease. In this study, using an experimental mouse model of psoriasis induced by imiquimod (IM
Externí odkaz:
https://doaj.org/article/87f74b38fc22499a8871bf841c4e897f
Autor:
Eliška Vrbová, Linda Grillová, Lenka Mikalová, Petra Pospíšilová, Radim Strnadel, Eliška Dastychová, Martina Kojanová, Miluše Kreidlová, Daniela Vaňousová, Filip Rob, Přemysl Procházka, Alena Krchňáková, Vladimír Vašků, Vladana Woznicová, Monika Dvořáková Heroldová, Ivana Kuklová, Hana Zákoucká, David Šmajs
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0217611 (2019)
A recently introduced Multilocus Sequence Typing scheme for Treponema pallidum subsp. pallidum was applied to clinical samples collected from 2004 to 2017 from the two largest cities (Prague and Brno) in the Czech Republic. Altogether, a total of 675
Externí odkaz:
https://doaj.org/article/b72f6a928fc24bc9bcfe0916ee670836