Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Filip Pattyn"'
Autor:
Steve Lefever, Filip Pattyn, Bram De Wilde, Frauke Coppieters, Sarah De Keulenaer, Jan Hellemans, Jo Vandesompele
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Although the sequencing landscape is rapidly evolving and sequencing costs are continuously decreasing, whole genome sequencing is still too expensive for use on a routine basis. Targeted resequencing of only the regions of intere
Externí odkaz:
https://doaj.org/article/b74e822f3bf3426cabe7791055bb39dc
Autor:
Ali Rihani, Tom Van Maerken, Filip Pattyn, Gert Van Peer, Anneleen Beckers, Sara De Brouwer, Candy Kumps, Evelien Mets, Joni Van der Meulen, Pieter Rondou, Carina Leonelli, Pieter Mestdagh, Frank Speleman, Jo Vandesompele
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71776 (2013)
BACKGROUND: Measuring messenger RNA (mRNA) levels using the reverse transcription quantitative polymerase chain reaction (RT-qPCR) is common practice in many laboratories. A specific set of mRNAs as internal control reference genes is considered as t
Externí odkaz:
https://doaj.org/article/bb6c9114c6fd4232a701296f6f2866ff
Autor:
Candy Kumps, Annelies Fieuw, Pieter Mestdagh, Björn Menten, Steve Lefever, Filip Pattyn, Sara De Brouwer, Tom Sante, Johannes Hubertus Schulte, Alexander Schramm, Nadine Van Roy, Tom Van Maerken, Rosa Noguera, Valérie Combaret, Christine Devalck, Frank Westermann, Geneviève Laureys, Angelika Eggert, Jo Vandesompele, Katleen De Preter, Frank Speleman
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52321 (2013)
Neuroblastoma is an embryonic tumor arising from immature sympathetic nervous system cells. Recurrent genomic alterations include MYCN and ALK amplification as well as recurrent patterns of gains and losses of whole or large partial chromosome segmen
Externí odkaz:
https://doaj.org/article/a21cfe8ab66d4212bb3b532098e03569
Autor:
Kim De Leeneer, Joachim De Schrijver, Lieven Clement, Machteld Baetens, Steve Lefever, Sarah De Keulenaer, Wim Van Criekinge, Dieter Deforce, Filip Van Nieuwerburgh, Sofie Bekaert, Filip Pattyn, Bram De Wilde, Paul Coucke, Jo Vandesompele, Kathleen Claes, Jan Hellemans
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25531 (2011)
Despite improvements in terms of sequence quality and price per basepair, Sanger sequencing remains restricted to screening of individual disease genes. The development of massively parallel sequencing (MPS) technologies heralded an era in which mole
Externí odkaz:
https://doaj.org/article/1c7ea325314c4c078c8c55e56b1d228f
Autor:
Barbara D'haene, Catia Attanasio, Diane Beysen, Josée Dostie, Edmond Lemire, Philippe Bouchard, Michael Field, Kristie Jones, Birgit Lorenz, Björn Menten, Karen Buysse, Filip Pattyn, Marc Friedli, Catherine Ucla, Colette Rossier, Carine Wyss, Frank Speleman, Anne De Paepe, Job Dekker, Stylianos E Antonarakis, Elfride De Baere
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000522 (2009)
To date, the contribution of disrupted potentially cis-regulatory conserved non-coding sequences (CNCs) to human disease is most likely underestimated, as no systematic screens for putative deleterious variations in CNCs have been conducted. As a mod
Externí odkaz:
https://doaj.org/article/ae6f29c6be8c46bf9b53ff13a30398fb
Autor:
Frank Speleman, Jo Vandesompele, Angelika Eggert, Alexander Schramm, Filip Pattyn, Tom Van Maerken, Sara De Brouwer, Katleen De Preter
Purpose: Neuroblastoma is a heterogeneous childhood tumor with poor survival outcome for the aggressive type despite intensive multimodal therapies. In this study, we aimed to identify new treatment options for neuroblastoma based on integrative geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1854d28bda5c092189cd94ffa604bf
https://doi.org/10.1158/1078-0432.c.6517924
https://doi.org/10.1158/1078-0432.c.6517924
Autor:
Frank Speleman, Jo Vandesompele, Angelika Eggert, Alexander Schramm, Filip Pattyn, Tom Van Maerken, Sara De Brouwer, Katleen De Preter
Supplementary Data from Meta-mining of Neuroblastoma and Neuroblast Gene Expression Profiles Reveals Candidate Therapeutic Compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f748f5a5b6fbee2c231e4f06c165784
https://doi.org/10.1158/1078-0432.22440622
https://doi.org/10.1158/1078-0432.22440622
Publikováno v:
EXPERT SYSTEMS WITH APPLICATIONS
In this paper, a dynamic setting for data quality improvement is studied. In such a setting, there is a repeated search for data quality rules and a fix of their violations until stability is reached. The constraints considered here are simple consta
Autor:
Bart Devreese, Katarzyna Ciesielska, Robin Geys, Lisa Van Renterghem, Sofie Lodens, Wim Soetaert, Evelien Derynck, Lynn Vanhaecke, Karolien Maes, Sophie Roelants, Sven Dierickx, Sofie De Maeseneire, Filip Pattyn, Léopold Mottet
Publikováno v:
Biotechnology and bioengineeringREFERENCES. 117(2)
Glucolipids (GLs) are glycolipid biosurfactants with promising properties. These GLs are composed of glucose attached to a hydroxy fatty acid through a omega and/or omega-1 glycosidic linkage. Up until today these interesting molecules could only be
Autor:
Bram De Wilde, Jo Vandesompele, Sarah De Keulenaer, Filip Pattyn, Frauke Coppieters, Jan Hellemans, Steve Lefever
Publikováno v:
BMC Bioinformatics
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
BMC BIOINFORMATICS
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-9 (2017)
BMC BIOINFORMATICS
Background Although the sequencing landscape is rapidly evolving and sequencing costs are continuously decreasing, whole genome sequencing is still too expensive for use on a routine basis. Targeted resequencing of only the regions of interest decrea