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Akademický článek

Dopamine release in human associative striatum during reversal learning

Autor: Filip Grill, Marc Guitart-Masip, Jarkko Johansson, Lars Stiernman, Jan Axelsson, Lars Nyberg, Anna Rieckmann

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)

Abstract The dopaminergic system is firmly implicated in reversal learning but human measurements of dopamine release as a correlate of reversal learning success are lacking. Dopamine release and hemodynamic brain activity in response to unexpected c

Externí odkaz: https://doaj.org/article/9a0f8326dd7d4694a656bcc2e908b463

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Akademický článek

Dissecting Motor and Cognitive Component Processes of a Finger-Tapping Task With Hybrid Dopamine Positron Emission Tomography and Functional Magnetic Resonance Imaging

Autor: Filip Grill, Jarkko Johansson, Jan Axelsson, Patrik Brynolfsson, Lars Nyberg, Anna Rieckmann

Publikováno v: Frontiers in Human Neuroscience, Vol 15 (2021)

Striatal dopamine is involved in facilitation of motor action as well as various cognitive and emotional functions. Positron emission tomography (PET) is the primary imaging method used to investigate dopamine function in humans. Previous PET studies

Externí odkaz: https://doaj.org/article/201e33876f1741ac9cdb3995e0398f4d

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Akademický článek

Neural correlates of reward processing: Functional dissociation of two components within the ventral striatum

Autor: Filip Grill, Lars Nyberg, Anna Rieckmann

Publikováno v: Brain and Behavior, Vol 11, Iss 2, Pp n/a-n/a (2021)

Abstract Introduction Rewarding and punishing stimuli elicit BOLD responses in the affective division of the striatum. The responses typically traverse from the affective to the associative division of the striatum, suggesting an involvement of assoc

Externí odkaz: https://doaj.org/article/74e510b40ccc45a880118b8dfbc5d26e

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Widespread fMRI BOLD Signal Overactivations during Cognitive Control in Older Adults Are Not Matched by Corresponding Increases in fPET Glucose Metabolism

Autor: Lars Stiernman, Filip Grill, Charlotte McNulty, Philip Bahrd, Vania Panes Lundmark, Jan Axelsson, Alireza Salami, Anna Rieckmann

Publikováno v: The Journal of Neuroscience. 43:2527-2536

A common observation in fMRI studies using the BOLD signal is that older adults, compared with young adults, show overactivations, particularly during less demanding tasks. The neuronal underpinnings of such overactivations are not known, but a domin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf8d6d345526d8704e75bdaa317c100
https://doi.org/10.1523/jneurosci.1331-22.2023

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Two long-axis dimensions of hippocampal cortical integration support memory function across the adult lifespan

Autor: Kristin Nordin, Robin Pedersen, Farshad Falahati, Jarkko Johansson, Filip Grill, Micael Andersson, Saana Korkki, Lars Bäckman, Andrew Zalesky, Anna Rieckmann, Lars Nyberg, Alireza Salami

The hippocampus is a complex structure critically involved in numerous behavior-regulating systems. A multidimensional account of the hippocampus functional integration with neocortex, however, remains to be established and evaluated in terms of func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ae146b2ef3ba984675922526f03ff05
https://doi.org/10.1101/2023.03.24.534115

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Deep brain stimulation does not modulate fMRI resting-state functional connectivity in essential tremor

Autor: Amar Awad, Filip Grill, Patric Blomstedt, Lars Nyberg, Johan Eriksson

BackgroundWhile the effectiveness of deep brain stimulation (DBS) in alleviating essential tremor (ET) is well-established, the underlying mechanisms of the treatment are unclear. ET, as characterised by tremor during action, is proposed to be driven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6e550b52ee1ee296fba139da7bd247b
https://doi.org/10.1101/2023.02.02.23285325

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Nonconscious information can be identified as task-relevant but not prioritized in working memory

Autor: Tiziana Pedale, Aurelie Fontan, Filip Grill, Fredrik Bergström, Johan Eriksson

Publikováno v: Cerebral cortex (New York, N.Y. : 1991).

Two critical features of working memory are the identification and appropriate use of task-relevant information while avoiding distraction. Here, in 3 experiments, we explored if these features can be achieved also for nonconscious stimuli. Participa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679ea5d460e1620994e6e47a377aad10
https://pubmed.ncbi.nlm.nih.gov/35667703

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Dissociations between glucose metabolism and blood oxygenation in the human default mode network revealed by simultaneous PET-fMRI

Autor: Lucas Rischka, Rupert Lanzenberger, Filip Grill, Katrine Riklund, Lars Jonasson Stiernman, Anna Rieckmann, Andreas Hahn, Jan Axelsson, Vania Panes Lundmark

Publikováno v: Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences

Significance A consistent finding from functional MRI (fMRI) of externally focused cognitive control is negative signal change in the brain’s default mode network (DMN), but it is unknown whether this reflects an increase of synaptic activity durin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ac25a77e37c61fb326aa8309ce89989
https://pubmed.ncbi.nlm.nih.gov/34404722

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