Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Filip Bergqvist"'
Autor:
Julia Steinmetz-Späh, Jianyang Liu, Rajkumar Singh, Maria Ekoff, Sanjaykumar Boddul, Xiao Tang, Filip Bergqvist, Helena Idborg, Pascal Heitel, Elin Rönnberg, Daniel Merk, Fredrik Wermeling, Jesper Z. Haeggström, Gunnar Nilsson, Dieter Steinhilber, Karin Larsson, Marina Korotkova, Per-Johan Jakobsson
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 12, Pp 100310- (2022)
Inhibition of microsomal prostaglandin E synthase-1 (mPGES-1) results in decreased production of proinflammatory PGE2 and can lead to shunting of PGH2 into the prostaglandin D2 (PGD2)/15-deoxy-Δ12,14-prostaglandin J2 (15dPGJ2) pathway. 15dPGJ2 forms
Externí odkaz:
https://doaj.org/article/21de76dd4fea476cb4a8cc5faaeadde7
Autor:
Filip Bergqvist, Andrew J. Carr, Kim Wheway, Bridget Watkins, Udo Oppermann, Per-Johan Jakobsson, Stephanie G. Dakin
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background Tendon disease is a significant global healthcare burden whereby patients experience pain and disability; however, the mechanisms that underlie inflammation and pain are poorly understood. Herein, we investigated the role of prost
Externí odkaz:
https://doaj.org/article/73d04a215b7f49c39107903d16123640
Autor:
Filip Bergqvist, Yvonne Sundström, Ming-Mei Shang, Iva Gunnarsson, Ingrid E. Lundberg, Michael Sundström, Per-Johan Jakobsson, Louise Berg
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
We screened 57 chemical probes, high-quality tool compounds, and relevant clinically used drugs to investigate their effect on pro-inflammatory prostaglandin E2 (PGE2) production and interleukin-8 (IL-8) secretion in human whole blood. Freshly drawn
Externí odkaz:
https://doaj.org/article/a871bd4cbdc64a2aa5a43d6a1789ca85
Autor:
Anna Kock, Karin Larsson, Filip Bergqvist, Nina Eissler, Lotta H.M. Elfman, Joan Raouf, Marina Korotkova, John Inge Johnsen, Per-Johan Jakobsson, Per Kogner
Publikováno v:
EBioMedicine, Vol 32, Iss , Pp 84-92 (2018)
Despite recent progress in diagnosis and treatment, survival for children with high-risk metastatic neuroblastoma is still poor. Prostaglandin E2 (PGE2)-driven inflammation promotes tumor growth, immune suppression, angiogenesis and resistance to est
Externí odkaz:
https://doaj.org/article/99f83daebaf54547bf01606d7d19935b
Autor:
Filip Bergqvist, Elena Ossipova, Helena Idborg, Joan Raouf, Antonio Checa, Karin Englund, Petter Englund, Payam Emami Khoonsari, Kim Kultima, Craig E. Wheelock, Karin Larsson, Marina Korotkova, Per-Johan Jakobsson
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Pharmacological inhibition of microsomal prostaglandin E synthase (mPGES)-1 for selective reduction in prostaglandin E2 (PGE2) biosynthesis is protective in experimental models of cancer and inflammation. Targeting mPGES-1 is envisioned as a safer al
Externí odkaz:
https://doaj.org/article/61eaede2cab142369d14f7796be1c194
Autor:
Joan Raouf, Nazmi Rafique, Michael Christopher Goodman, Helena Idborg, Filip Bergqvist, Richard N Armstrong, Per-Johan Jakobsson, Ralf Morgenstern, Linda Spahiu
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163600 (2016)
Prostaglandins are signaling molecules that regulate different physiological processes, involving allergic and inflammatory responses and cardiovascular control. They are involved in several pathophysiological processes, including inflammation and ca
Externí odkaz:
https://doaj.org/article/63a6533c22e74d41aaae4e545752e84f
Autor:
John Inge Johnsen, Per-Johan Jakobsson, Karin Larsson, Marina Korotkova, Julia Steinmetz, Per Kogner, Anna Kock, Lotta Elfman, Filip Bergqvist
Publikováno v:
The FASEB Journal. 34:11101-11114
The majority of anti-cancer therapies target the proliferating tumor cells, while the tumor stroma, principally unaffected, survives, and provide a niche for surviving tumor cells. Combining tumor cell and stroma-targeting therapies thus have a poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e13bd2e5523fe21f972a6252d719011b
https://doi.org/10.1096/fj.202000684r
https://doi.org/10.1096/fj.202000684r
Autor:
Linda Ljungblad, Filip Bergqvist, Conny Tümmler, Samanthi Madawala, Thale Kristin Olsen, Teodora Andonova, Per-Johan Jakobsson, John Inge Johnsen, Jana Pickova, Birgitta Strandvik, Per Kogner, Helena Gleissman, Malin Wickström
Aims: Medulloblastoma (MB) is one of the most common malignant central nervous system tumors of childhood. Despite intensive treatments that often leads to severe neurological sequelae, the risk for resistant relapses remains significant. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4e20730ed6dc7bfb61d9eb7f549edf3
https://pub.epsilon.slu.se/27813/
https://pub.epsilon.slu.se/27813/
Autor:
Linda, Ljungblad, Filip, Bergqvist, Conny, Tümmler, Samanthi, Madawala, Thale Kristin, Olsen, Teodora, Andonova, Per-Johan, Jakobsson, John Inge, Johnsen, Jana, Pickova, Birgitta, Strandvik, Per, Kogner, Helena, Gleissman, Malin, Wickström
Publikováno v:
Life sciences. 295
Medulloblastoma (MB) is one of the most common malignant central nervous system tumors of childhood. Despite intensive treatments that often leads to severe neurological sequelae, the risk for resistant relapses remains significant. In this study we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbd9071628cac7470807d1b727e2820c
https://pubmed.ncbi.nlm.nih.gov/35157910
https://pubmed.ncbi.nlm.nih.gov/35157910
Autor:
Iva Gunnarsson, Per-Johan Jakobsson, Louise Berg, Filip Bergqvist, Ingrid E. Lundberg, Ming-Mei Shang, Michael Sundström, Yvonne Sundström
We screened 57 chemical probes, high-quality tool compounds, and relevant clinically used drugs to investigate their effect on pro-inflammatory prostaglandin E2 (PGE2) production and interleukin-8 (IL-8) secretion in human whole blood. Freshly drawn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb48674be9b44219446f78919c48ca5
https://doi.org/10.1101/2019.12.30.890715
https://doi.org/10.1101/2019.12.30.890715