Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Filip Šenigl"'
Autor:
Anna Koslová, Pavel Trefil, Jitka Mucksová, Veronika Krchlíková, Jiří Plachý, Jakub Krijt, Markéta Reinišová, Dana Kučerová, Josef Geryk, Jiří Kalina, Filip Šenigl, Daniel Elleder, Viktor Kožich, Jiří Hejnar
Publikováno v:
Viruses, Vol 13, Iss 12, p 2504 (2021)
The chicken Tva cell surface protein, a member of the low-density lipoprotein receptor family, has been identified as an entry receptor for avian leukosis virus of classic subgroup A and newly emerging subgroup K. Because both viruses represent an im
Externí odkaz:
https://doaj.org/article/dfebb64862e64b58b3293fd1b2c3fcfe
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150589 (2016)
J subgroup avian leukosis virus (ALV-J) infects domestic chicken, jungle fowl, and turkey and enters the host cell through a receptor encoded by tvj locus and identified as Na+/H+ exchanger 1 (NHE1). The resistance to ALV-J in a great majority of exa
Externí odkaz:
https://doaj.org/article/dd7698de1e7348b291853f7cb79801c0
Publikováno v:
Viruses, Vol 10, Iss 3, p 116 (2018)
Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long
Externí odkaz:
https://doaj.org/article/ba1c4bf7ccca4f97818d3a06c57b7f5c
Autor:
Alina Tarsalainen, Anni Soikkeli, Frederic W Alt, Minna K. Kyläniemi, Jessica J. McDonald, David G. Schatz, Fei-Long Meng, Paulina Budzynska, Yaakov Maman, Filip Šenigl, Jukka Alinikula
Publikováno v:
The Journal of Immunology. 208:143-154
Somatic hypermutation (SHM) drives the genetic diversity of Ig genes in activated B cells and supports the generation of Abs with increased affinity for Ag. SHM is targeted to Ig genes by their enhancers (diversification activators [DIVACs]), but how
Autor:
David G. Schatz, Alina Tarsalainen, Minna K. Kyläniemi, Jessica J. McDonald, Frederic W. Alt, Fei-Long Meng, Jukka Alinikula, Paulina Budzynska, Anni Soikkeli, Yaakov Maman, Filip Šenigl
Somatic hypermutation (SHM) drives the genetic diversity of immunoglobulin (Ig) genes in activated B cells and supports the generation of antibodies with increased affinity for antigen. SHM is targeted to Ig genes by their enhancers (DIVACs; diversif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11723cc05ee32f54f7d25f8aa598c6e4
https://doi.org/10.1101/2021.09.16.460442
https://doi.org/10.1101/2021.09.16.460442
Autor:
Ewa Pavlova, N. Dvorakova, S. S. Rohiwal, D. Babuka, Miroslav Šlouf, Michaela Vaskovicova, Knut Stieger, H. Benes, P. Stepanek, Jiří Klíma, Filip Šenigl, Zdenka Ellederova
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Clustered regularly interspaced short palindromic repeats-associated protein (CRISPR/Cas9) system has become a revolutionary tool for gene editing. Since viral delivery systems have significant side effects, and naked DNA delivery is not an option, t
Autor:
Anoj Ilanges, Jeffrey Shabanowitz, David G. Schatz, Benjamin Barnhill, Jukka Alinikula, Filip Šenigl, Lizhen Wu, Daniel A. Michelson, Ravi K. Dinesh, Donald F. Hunt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4cf6f6a9dd5b6fa33e985e52a3ab8f08
https://doi.org/10.1002/eji.201948357/v2/response1
https://doi.org/10.1002/eji.201948357/v2/response1
Autor:
Jiří Plachý, Dana Kučerová, Markéta Reinišová, David Přikryl, Anna Koslová, Jiří Hejnar, Filip Šenigl
Publikováno v:
Journal of Virology. 93
Avian leukosis virus subgroup K (ALV-K) is composed of newly emerging isolates, which, in sequence analyses, cluster separately from the well-characterized subgroups A, B, C, D, E, and J. However, it remains unclear whether ALV-K represents an indepe
Autor:
Ravi K. Dinesh, Daniel A. Michelson, Benjamin Barnhill, David G. Schatz, Donald F. Hunt, Anoj Ilanges, Jukka Alinikula, Jeffrey Shabanowitz, Lizhen Wu, Filip Šenigl
Publikováno v:
Eur J Immunol
Secondary diversification of the immunoglobulin (Ig) repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)—three processes that are initiated by activation-induced cytidine deaminase (AID
Autor:
David G. Schatz, Jean-Marie Buerstedde, Suhas S.P. Rao, Jukka Alinikula, Filip Šenigl, Yaakov Maman, Ravi K. Dinesh, Lubomira Pecnova, David Weisz, Jiri Hejnar, Rafael Casellas, Rashu B. Seth, Arina D. Omer, Erez Lieberman Aiden
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 12, Pp 3902-3915.e8 (2019)
Cell Reports, Vol 29, Iss 12, Pp 3902-3915.e8 (2019)
SUMMARY Somatic hypermutation (SHM) introduces point mutations into immunoglobulin (Ig) genes but also causes mutations in other parts of the genome. We have used lentiviral SHM reporter vectors to identify regions of the genome that are susceptible