Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Filip, Roudnicky"'
Autor:
Filip Roudnicky, Maija Hollmén
Publikováno v:
Genomics Data, Vol 8, Iss C, Pp 1-3 (2016)
Macrophages are important mediators of tumor progression and their function is broadly influenced by different microenvironmental stimuli. To understand the molecular basis of the tumor-supporting role of macrophages in aggressive breast cancer we co
Externí odkaz:
https://doaj.org/article/c478ca49293b4d1aa4b947689c477210
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2475
Difficulties with poor reproducibility and translatability of animal model-based research, along with increased efforts to abide by the 3Rs tenet of animal welfare, are driving demand for more relevant human cellular systems. This is especially true
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67be0daab426bfc13950528f70ea1143
https://pubmed.ncbi.nlm.nih.gov/35451764
https://pubmed.ncbi.nlm.nih.gov/35451764
Autor:
Leonard D. Goldstein, Filip Roudnicky, Bo Kyoung Kim, Claas A. Meyer, Lisa Sach-Peltason, Nikhil J. Pandya, Klaus Christensen, Christoph Patsch, Héloïse Ragelle, Oliv Eidam, Chad A. Cowan, Martin Graf, Pamela Strassburger, Zora Modrusan, Mark Burcin, Balazs Banfai, Verena Kueppers, Manuel Tzouros, Mirjana Lazendic, Sabine Uhles, Gregor Sturm, Peter D. Westenskow, Franco Revelant, Yanjun Lan, Jitao David Zhang, Sabine Gruener
Publikováno v:
Proc Natl Acad Sci U S A
The blood–retina barrier and blood–brain barrier (BRB/BBB) are selective and semipermeable and are critical for supporting and protecting central nervous system (CNS)-resident cells. Endothelial cells (ECs) within the BRB/BBB are tightly coupled,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2681eba3f4ec57913642788bbe14e23c
https://doi.org/10.1073/pnas.1911532117
https://doi.org/10.1073/pnas.1911532117
Autor:
Benjamin Haley, Filip Roudnicky
Publikováno v:
Cancer Cell. 38:31-43
Functional genomics describes a field of biology that uses a range of approaches for assessing gene function with high-throughput molecular, genetic, and cellular technologies. The near limitless potential for applying these concepts to study the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a2fbe4032e2d7813639d46eb966763
https://doi.org/10.1016/j.ccell.2020.04.006
https://doi.org/10.1016/j.ccell.2020.04.006
Publikováno v:
Methods in Molecular Biology ISBN: 9781071622162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50fc5433ce42ca38c59a98dad2e102a5
https://doi.org/10.1007/978-1-0716-2217-9_19
https://doi.org/10.1007/978-1-0716-2217-9_19
Autor:
Michael Detmar, Vivianne I. Otto, Filip Roudnicky, Cédric Poyet, Lorenz Buser, Peter J. Wild, Karim Saba
Publikováno v:
The American journal of pathology. 190(9)
Tumor-associated blood vessels differ from normal vessels and play key roles in tumor progression. We aimed to identify biomolecules that are expressed differentially in human bladder cancer-associated blood vessels to find novel biomarkers and mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c1f99cb163ffaceacea4ccd35efb5ca
https://pubmed.ncbi.nlm.nih.gov/32585158
https://pubmed.ncbi.nlm.nih.gov/32585158
Autor:
Claas A. Meyer, Chad A. Cowan, Mark Burcin, Peter D. Westenskow, Roland Schmucki, Verena Küppers, Christoph Patsch, Yanjun Lan, Martin Graf, Bo Kyoung Kim, Klaus Christensen, Filip Roudnicky
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Endothelial cells (ECs) display remarkable plasticity during development before becoming quiescent and functionally mature. EC maturation is directed by several known transcription factors (TFs), but the specific set of TFs responsible for promoting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06480fb34d3baf3123480056c02c66da
https://doi.org/10.1038/s41598-020-60688-x
https://doi.org/10.1038/s41598-020-60688-x
Autor:
Susanna Poghosyan, Giorgia Vella, Samia B. Bachmann, Michael Detmar, Jay W. Shin, Simon Schwager, Sun Young Yoon, Cédric Poyet, Sinem Karaman, Vivianne I. Otto, Filip Roudnicky
Publikováno v:
Oncogene
ResearcherID
Oncogene, 37 (19)
ResearcherID
Oncogene, 37 (19)
Thrombospondin-2 (TSP2) is an anti-angiogenic matricellular protein that inhibits tumor growth and angiogenesis. Tumor-associated blood vascular endothelial cells (BECs) were isolated from human invasive bladder cancers and from matched normal bladde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c51437872c9fd7df757117ee10e5391
http://europepmc.org/articles/PMC5945577
http://europepmc.org/articles/PMC5945577
Autor:
Vivianne I. Otto, Dave Tang, Lothar C. Dieterich, Cédric Poyet, Peter Camenzind, Lorenz Buser, Chien Hsien Ho, Peter J. Wild, Filip Roudnicky, Michael Detmar
Publikováno v:
The Journal of Pathology. 242:193-205
Bladder cancer is a frequently recurring disease with a very poor prognosis once progressed to invasive stages, and tumour-associated blood vessels play a crucial role in this process. In order to identify novel biomarkers associated with progression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fda0f60231543b31e910c1f74293ff1
https://doi.org/10.1002/path.4892
https://doi.org/10.1002/path.4892
Autor:
Gregor Dernick, Chad A. Cowan, Natalie Bordag, Jitao David Zhang, Claas A. Meyer, Antje Wagner-Golbs, Max Friesen, Mark Burcin, Martin Ebeling, Yanjun Lan, Martin Graf, Christoph Patsch, Klaus Christensen, Filip Roudnicky, Andreas Staempfli
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 24
Volume 20
Issue 24
The kinase AKT2 (PKB) is an important mediator of insulin signaling, for which loss-of-function knockout (KO) mutants lead to early onset diabetes mellitus, and dominant active mutations lead to early development of obesity and endothelial cell (EC)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08254e6af1c61b3178595ea998f7a3c2