Zobrazeno 1 - 10
of 4 033
pro vyhledávání: '"Filamin-A"'
Autor:
Xi Wang, Qiyu Jia, Li Yu, Jinyong Huang, Xin Wang, Lijun Zhou, Wubulikasimu Mijiti, Zhenzi Xie, Shiming Dong, Zengru Xie, Hairong Ma
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39334- (2024)
Objective: Filamin B (FLNB) encodes an actin-binding protein that is known to function as a novel RNA-binding protein involved in cell movement and signal transduction and plays a pivotal role in bone growth. This study aimed to investigate possible
Externí odkaz:
https://doaj.org/article/0fb1f24bbc274fd9b0004d0d1e92e055
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundPeriventricular nodular heterotopia (PVNH) is a neuronal migration disorder caused by the inability of neurons to move to the cortex. Patients with PVNH often experience epilepsy due to ectopic neuronal discharges. Most cases of PVNH are as
Externí odkaz:
https://doaj.org/article/289cee2efab74e559779162d4a57b07b
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 4, Pp 3408-3423 (2024)
Despite ongoing research in the field of breast cancer, the morbidity rates indicate that the disease remains a significant challenge. While patients with primary tumors have relatively high survival rates, these chances significantly decrease once m
Externí odkaz:
https://doaj.org/article/3b89a91d2de0401b8a748d9a01fffd2e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Critical periods are temporally-restricted, early-life windows when sensory experience remodels synaptic connectivity to optimize environmental input. In the Drosophila juvenile brain, critical period experience drives synapse elimination, w
Externí odkaz:
https://doaj.org/article/8225cef896694fd7bc71493e99ac83b6
Publikováno v:
Cancer Biology & Therapy, Vol 25, Iss 1 (2024)
The incidence of intrahepatic cholangiocarcinoma (ICC) is steadily rising, and it is associated with a high mortality rate. Clinical samples were collected to detect the expression of HSPB8 and BAG3 in ICC tissues. ICC cells were cultured and transfe
Externí odkaz:
https://doaj.org/article/11340e49339843848a5cc45bdf1af7c9
Akademický článek
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Akademický článek
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Autor:
Ming Hui Chen, Ellen S. Deng, Jessica M. Yamada, Sangita Choudhury, Julia Scotellaro, Lily Kelley, Eric Isselbacher, Mark E. Lindsay, Christopher A. Walsh, Ryan N. Doan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Thoracic aortic aneurysm (TAA) is associated with significant morbidity and mortality. Although individuals with family histories of TAA often undergo clinical molecular genetic testing, adults with nonsyndromic TAA are not typically evalu
Externí odkaz:
https://doaj.org/article/882e211948344b91ba18864ae800da39
Autor:
Sophie J. Featherby, Camille Ettelaie
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
IntroductionMicrovesicles (MV) released by endothelial cells (EC) following injury or inflammation contain tissue factor (TF) and mediate communication with the underlying smooth muscle cells (SMC). Ser253-phosphorylated TF co-localizes with filamin
Externí odkaz:
https://doaj.org/article/cff5534a0e06457f91a767c663e2afb1
Autor:
Joyce C. Ohiri, Lisa Dellefave‐Castillo, Garima Tomar, Lisa Wilsbacher, Lubna Choudhury, David Y. Barefield, Dominic Fullenkamp, Anthony M. Gacita, Tanner O. Monroe, Lorenzo Pesce, Malorie Blancard, Lauren Vaught, Alfred L. George, Alexis R. Demonbreun, Megan J. Puckelwartz, Elizabeth M. McNally
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 10 (2024)
Background Many cardiomyopathy‐associated FLNC pathogenic variants are heterozygous truncations, and FLNC pathogenic variants are associated with arrhythmias. Arrhythmia triggers in filaminopathy are incompletely understood. Methods and Results We
Externí odkaz:
https://doaj.org/article/f77896bb0287466494c3807c1849c7e0