Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Filamin binding"'
Publikováno v:
Biochimica et biophysica acta. General subjects. 1865(12)
Background Cytoskeletal protein filamin A is critical for the outside-in signaling of integrins. Although molecular mechanisms of filamin-integrin interactions are not fully understood. Mostly, the membrane distal (MD) part of the cytosolic tail (CT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6fd2291729ee90bfe48b45f9317c655
https://pubmed.ncbi.nlm.nih.gov/34509570
https://pubmed.ncbi.nlm.nih.gov/34509570
Publikováno v:
Cancer biotherapyradiopharmaceuticals.
Background: Hepatocellular carcinoma (HCC) is the most common form of liver cancer. Circular RNAs (circRNAs) play a vital role in cancer development and progression. This study aimed to investigate the role and potential mechanism of circRNA filamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5cbe2fc0266b994e2ad9f7ee90ba959
https://pubmed.ncbi.nlm.nih.gov/32907351
https://pubmed.ncbi.nlm.nih.gov/32907351
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116 (35), 17336–17344
Global changes in the state of spatially distributed systems can often be traced back to perturbations that arise locally. Whether such local perturbations grow into global changes depends on the system geometry and the spatial spreading of these per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8df76fe564af8fb724b173a81f50029
https://pubmed.ncbi.nlm.nih.gov/31405981
https://pubmed.ncbi.nlm.nih.gov/31405981
Akademický článek
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Autor:
Aldema Sas-Chen, Michal Sheffer, Oscar M. Rueda, Nava Nevo, Ori Heyman, Yosef Yarden, Mattia Lauriola, Davide Gnocchi, Carlos Caldas, Sara Lavi, Yehoshua Enuka, Gur Pines, Lee Roth, Moshit Lindzen, Swati Srivastava, Arie Admon, Gabi Tarcic, Tamar Ziv, Maicol Mancini, Ashish Noronha, Eli Pikarsky
Publikováno v:
Science signaling. 11(515)
Mutations mimicking growth factorâinduced proliferation and motility characterize aggressive subtypes of mammary tumors. To unravel currently unknown players in these processes, we performed phosphoproteomic analysis on untransformed mammary epi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e7657e7fc5bd6c90dcb8c94f5b3846
https://pubmed.ncbi.nlm.nih.gov/29382783
https://pubmed.ncbi.nlm.nih.gov/29382783
Autor:
Ralph T. Böttcher, Hui-yuan Tseng, Roy Zent, Anna V. Samarelli, Markus Sperandio, Roland Immler, Tilman Ziegler, Reinhard Fässler, Sarah Scholze, Charles R. Sanders, Patricia Kammerer
Publikováno v:
Journal of Cell Science.
Integrins are α/β heterodimers that interconvert between inactive and active states. In the active state the α/β cytoplasmic domains recruit integrin-activating proteins and separate the transmembrane and cytoplasmic (TMcyto) domains (unclasped T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2353566cae4eac2b752dc2799ae090
https://doi.org/10.1242/jcs.218214
https://doi.org/10.1242/jcs.218214
Autor:
Ho-Geun Yoon, Ok-Hee Lee, Yun Mi Woo, Seung Hyun Oh, Soo-Kyung Bae, Youngsok Choi, Jinkyoung Lee, Keun Ho Lee, Ju-Hee Kang, Zhou Songyang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1853:409-421
The tripartite motif containing (TRIM) proteins are a large family of proteins that have been implicated in many biological processes including cell differentiation, apoptosis, transcriptional regulation, and signaling pathways. Here, we show that TR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fec8976fd889ef27309bb7699eac06
https://doi.org/10.1016/j.bbamcr.2014.11.007
https://doi.org/10.1016/j.bbamcr.2014.11.007
Publikováno v:
Integrative Biology. 7:1285-1296
Filamin plays a key role in cellular biomechanics as an actin cross-linker and as a versatile focal adhesion binding partner. It binds directly to integrins, a family of mechanosensitive transmembrane receptors that mediate attachment to several extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be17ada237db6cccf473176a47bf63c7
https://doi.org/10.1039/c5ib00133a
https://doi.org/10.1039/c5ib00133a
Akademický článek
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