Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Fikru B"'
Autor:
Fikru B. Bedada, Brian R. Thompson, Jennifer L. Mikkila, Sunny S.-K. Chan, Si Ho Choi, Erik A. Toso, Michael Kyba, Joseph M. Metzger
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Human induced pluripotent stem cells and their differentiation into cardiac myocytes (hiPSC-CMs) provides a unique and valuable platform for studies of cardiac muscle structure–function. This includes studies centered on disease etiology,
Externí odkaz:
https://doaj.org/article/62a45a61bcc04174b4a0815bbbae4f4f
Publikováno v:
Frontiers in Molecular Medicine, Vol 2 (2022)
SARS-CoV-2 is a novel zoonotic positive-sense RNA virus (ssRNA+) belonging to the genus beta coronaviruses (CoVs) in the Coronaviridae family. It is the causative agent for the outbreak of the disease, COVID-19. It is the third CoV causing pneumonia
Externí odkaz:
https://doaj.org/article/856e6b15479348eb94ace2ecf6bd20df
Autor:
Julius S. Ngwa, Evaristus Nwulia, Oyonumo Ntekim, Fikru B. Bedada, Bernard Kwabi-Addo, Sheeba Nadarajah, Steven Johnson, William M. Southerland, John Kwagyan, Thomas O. Obisesan
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2022)
BackgroundDNA methylation at CpG sites is a vital epigenetic modification of the human genome affecting gene expression, and potentially, health outcomes. However, evidence is just budding on the effects of aerobic exercise-induced adaptation on DNA
Externí odkaz:
https://doaj.org/article/b126d8ea0b84418ca93fa8ca2d442de7
Autor:
Fikru B. Bedada, Oyonumo E. Ntekim, Evaristus O. Nwulia, Thomas V. Fungwe, Sheeba Raaj Nadarajah, Thomas O. Obisesan
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
The ubiquitin proteasome system (UPS) and FOXOs transcription factors play a pivotal role in cellular clearance and minimizing the accumulation of Aβ in neurodegeneration (ND). In African Americans (AAs) with mild cognitive impairment (MCI), the rol
Externí odkaz:
https://doaj.org/article/5538dbbcdab448a1913abe0b306fa64b
Autor:
Fikru B. Bedada, Sunny S-K. Chan, Stefania K. Metzger, Liying Zhang, Jianyi Zhang, Daniel J. Garry, Timothy J. Kamp, Michael Kyba, Joseph M. Metzger
Publikováno v:
Stem Cell Reports, Vol 3, Iss 4, Pp 594-605 (2014)
There is no consensus in the stem cell field as to what constitutes the mature cardiac myocyte. Thus, helping formalize a molecular signature for cardiac myocyte maturation would advance the field. In the mammalian heart, inactivation of the “fetal
Externí odkaz:
https://doaj.org/article/b0652b07b655457c902421bbf9a8c0ee
Autor:
Nathan J Palpant, Michael L Szatkowski, Wang Wang, DeWayne Townsend, Fikru B Bedada, Lauren G Koch, Steven L Britton, Joseph M Metzger
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6117 (2009)
Oxygen metabolism is a strong predictor of the general health and fitness of an organism. In this study, we hypothesized that a divergence in intrinsic aerobic fitness would co-segregate with susceptibility for cardiovascular dysfunction. To test thi
Externí odkaz:
https://doaj.org/article/d3e734dd020a4f488ebe4d29e14356d7
Autor:
Bedada, Fikru B.1,2 (AUTHOR), Thompson, Brian R.1 (AUTHOR), Mikkila, Jennifer L.1 (AUTHOR), Chan, Sunny S.-K.3 (AUTHOR), Choi, Si Ho3 (AUTHOR), Toso, Erik A.3 (AUTHOR), Kyba, Michael3 (AUTHOR), Metzger, Joseph M.1,3 (AUTHOR) metzgerj@umn.edu
Publikováno v:
Scientific Reports. 2/16/2024, Vol. 14 Issue 1, p1-13. 13p.
Autor:
Thomas V. Fungwe, Julius S. Ngwa, Steven P. Johnson, Jilian V. Turner, Mara I. Ramirez Ruiz, Oludolapo O. Ogunlana, Fikru B. Bedada, Sheeba Nadarajah, Oyonumo E. Ntekim, Thomas O. Obisesan
Publikováno v:
Dementia and Geriatric Cognitive Disorders. :1-8
Background: Cardiovascular disease (CVD), including elevated blood pressure (BP), is known to promote Alzheimer’s disease (AD) risk. Although brain amyloid load is a recognized hallmark of pre-symptomatic AD, its relationship to increased BP is les
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::41dfd80982ca86c10c5138c5594bdbaf
https://doi.org/10.1159/000528117
https://doi.org/10.1159/000528117
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Fikru B. Bedada, Joseph M. Metzger, Jennifer L. Mikkila, Matthew Wheelwright, Mohammad A. Mandegar, Brian R. Thompson
Publikováno v:
Stem Cells
Advancing maturation of stem cell-derived cardiac muscle represents a major barrier to progress in cardiac regenerative medicine. Cardiac muscle maturation involves a myriad of gene, protein, and cell-based transitions, spanning across all aspects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07eca4aea092a8a3d78b63ad434e959e
https://doi.org/10.1002/stem.3235
https://doi.org/10.1002/stem.3235