STAT3 signaling in B cells controls germinal center zone organization and recycling.

Autor: Fike AJ; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Chodisetti SB; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Wright NE; Department of Medicine, Section of Rheumatology and Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637, USA., Bricker KN; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Domeier PP; Center for Fundamental Immunology, Benaroya Research Institute, Seattle, WA 98101, USA., Maienschein-Cline M; Research Informatics Core, University of Illinois at Chicago, Chicago, IL 60607, USA., Rosenfeld AM; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA., Luckenbill SA; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Weber JL; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Choi NM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA., Luning Prak ET; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA., Mandal M; Department of Medicine, Section of Rheumatology and Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637, USA., Clark MR; Department of Medicine, Section of Rheumatology and Gwen Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL 60637, USA., Rahman ZSM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033, USA. Electronic address: zrahman@pennstatehelath.psu.edu.

Publikováno v: Cell reports [Cell Rep] 2023 May 30; Vol. 42 (5), pp. 112512. Date of Electronic Publication: 2023 May 16.

The mitochondrial sodium/calcium exchanger NCLX (Slc8b1) in B lymphocytes.

Autor: Emrich SM; Department of Cellular and Molecular Physiology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Yoast RE; Department of Cellular and Molecular Physiology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Fike AJ; Department of Microbiology and Immunology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Bricker KN; Department of Microbiology and Immunology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Xin P; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 1526, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 1526, USA., Zhang X; Department of Cellular and Molecular Physiology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Rahman ZSM; Department of Microbiology and Immunology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA., Trebak M; Department of Cellular and Molecular Physiology, the Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA 17033, USA; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 1526, USA; Vascular Medicine Institute, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 1526, USA. Electronic address: trebakm@pitt.edu.

Publikováno v: Cell calcium [Cell Calcium] 2022 Dec; Vol. 108, pp. 102667. Date of Electronic Publication: 2022 Oct 20.

STAT4 Is Largely Dispensable for Systemic Lupus Erythematosus-like Autoimmune- and Foreign Antigen-Driven Antibody-Forming Cell, Germinal Center, and Follicular Th Cell Responses.

Autor: Fike AJ; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Chodisetti SB; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Bricker KN; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Choi NM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Chroneos ZC; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033.; Department of Pediatrics, Pennsylvania State University College of Medicine, Hershey, PA 17033.; Pulmonary Immunology and Physiology Laboratory, Pennsylvania State University College of Medicine, Hershey, PA 17033; and., Kaplan MH; Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN 46202., Rahman ZSM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033; zrahman@pennstatehealth.psu.edu.

Publikováno v: ImmunoHorizons [Immunohorizons] 2021 Jan 14; Vol. 5 (1), pp. 2-15. Date of Electronic Publication: 2021 Jan 14.

The native ORAI channel trio underlies the diversity of Ca ²⁺ signaling events.

Autor: Yoast RE; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Emrich SM; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Zhang X; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Xin P; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Johnson MT; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Fike AJ; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Walter V; Department of Public Health Sciences, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA.; Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA.; Penn State Cancer Institute and The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Hempel N; Penn State Cancer Institute and The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA.; Department of Pharmacology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Yule DI; Department of Pharmacology and Physiology, University of Rochester Medical Center School of Medicine and Dentistry, 601 Elmwood Avenue, Box 711, Rochester, NY, 14642, USA., Sneyd J; Department of Mathematics, The University of Auckland, 38 Princes Street, Auckland, 1010, New Zealand., Gill DL; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA., Trebak M; Department of Cellular and Molecular Physiology, The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA. mtrebak@psu.edu.; Penn State Cancer Institute and The Pennsylvania State University College of Medicine, 500 University Drive, Hershey, PA, 17033, USA. mtrebak@psu.edu.

Publikováno v: Nature communications [Nat Commun] 2020 May 15; Vol. 11 (1), pp. 2444. Date of Electronic Publication: 2020 May 15.

Type II but Not Type I IFN Signaling Is Indispensable for TLR7-Promoted Development of Autoreactive B Cells and Systemic Autoimmunity.

Autor: Chodisetti SB; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Fike AJ; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Domeier PP; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Singh H; J. Craig Venter Institute, Rockville, MD 20850., Choi NM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033., Corradetti C; Rheumatology Division, Temple University, Philadelphia, PA 19122., Kawasawa YI; Department of Pharmacology, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033.; Department of Biochemistry and Molecular Biology, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033; and., Cooper TK; Department of Comparative Medicine, Pennsylvania State University College of Medicine, Hershey, PA 17033., Caricchio R; Rheumatology Division, Temple University, Philadelphia, PA 19122., Rahman ZSM; Department of Microbiology and Immunology, Pennsylvania State University College of Medicine, Hershey, PA 17033; zrahman@pennstatehealth.psu.edu.

Publikováno v: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2020 Feb 15; Vol. 204 (4), pp. 796-809. Date of Electronic Publication: 2020 Jan 03.