Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Fijneman, P."'
Autor:
Lakbir, Soufyan, Buranelli, Caterina, Meijer, Gerrit A., Heringa, Jaap, Fijneman, Remond J. A., Abeln, Sanne
Publikováno v:
Bioinformatics, Volume 40, Issue Supplement 2, September 2024, Pages ii37-ii44
Background: Genomic instability is a hallmark of cancer, leading to many somatic alterations. Identifying which alterations have a system-wide impact is a challenging task. Nevertheless, this is an essential first step for prioritizing potential biom
Externí odkaz:
http://arxiv.org/abs/2403.03829
Autor:
Astrid Kramer, Carmen Rubio‐Alarcón, Daan van denBroek, Daan C. L. Vessies, Iris van't Erve, Gerrit A. Meijer, Geraldine R. Vink, Ed Schuuring, Remond J. A. Fijneman, Veerle M. H. Coupé, Valesca P. Retèl
Publikováno v:
Molecular Oncology, Vol 18, Iss 11, Pp 2730-2742 (2024)
Circulating tumor DNA (ctDNA) detection has multiple promising applications in oncology, but the road toward implementation in clinical practice is unclear. We aimed to support the implementation process by exploring potential future pathways of ctDN
Externí odkaz:
https://doaj.org/article/4e90fa3c429847ecbf02abb2a149a0e3
Autor:
Iris van ’t Erve, Bahar Alipanahi, Keith Lumbard, Zachary L. Skidmore, Lorenzo Rinaldi, Laurel K. Millberg, Jacob Carey, Bryan Chesnick, Stephen Cristiano, Carter Portwood, Tony Wu, Erica Peters, Karen Bolhuis, Cornelis J. A. Punt, Jennifer Tom, Peter B. Bach, Nicholas C. Dracopoli, Gerrit A. Meijer, Robert B. Scharpf, Victor E. Velculescu, Remond J. A. Fijneman, Alessandro Leal
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Circulating cell-free DNA (cfDNA) assays for monitoring individuals with cancer typically rely on prior identification of tumor-specific mutations. Here, we develop a tumor-independent and mutation-independent approach (DELFI-tumor fraction,
Externí odkaz:
https://doaj.org/article/8005c4ee68144cd383ff212f1b67d00a
Autor:
K. Zwart, M.N.G.J.A. Braat, F.H. van der Baan, A.M. May, J.M.L. Roodhart, D. Al-Toma, J.M.M.B. Otten, M. Los, T. Oostergo, R.J.A. Fijneman, J.M. van Dodewaard-de Jong, C.J.A Punt, G. Meijer, J.J.W. Lagendijk, M. Koopman, M. Intven, G.M. Bol
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 49, Iss , Pp 100874- (2024)
Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasib
Externí odkaz:
https://doaj.org/article/ac10662617774f08b786a5328d64f299
Autor:
Astrid Kramer, Marjolein J. E. Greuter, Suzanna J. Schraa, Geraldine R. Vink, Jillian Phallen, Victor E. Velculescu, Gerrit A. Meijer, Daan van den Broek, Miriam Koopman, Jeanine M. L. Roodhart, Remond J. A. Fijneman, Valesca P. Retèl, Veerle M. H. Coupé
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
Background: Current patient selection for adjuvant chemotherapy (ACT) after curative surgery for stage II colon cancer (CC) is suboptimal, causing overtreatment of high-risk patients and undertreatment of low-risk patients. Postoperative circulating
Externí odkaz:
https://doaj.org/article/df477bb60b4f45289ac535ad731952c5
Autor:
Aleksandra Stanojevic, Jelena Spasic, Mladen Marinkovic, Suzana Stojanovic-Rundic, Radmila Jankovic, Ana Djuric, Jerome Zoidakis, Remond J. A. Fijneman, Sergi Castellvi-Bel, Milena Cavic
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Background: Methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms (SNPs) have been suggested as risk, prognostic, and predictive factors for colorectal cancer in various populations, but have not been validated so far. The aim o
Externí odkaz:
https://doaj.org/article/28344242e5054711ab1e8ccbb4f46225
Akademický článek
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Akademický článek
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Akademický článek
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Autor:
Mladen Marinkovic, Suzana Stojanovic-Rundic, Aleksandra Stanojevic, Marija Ostojic, Dusica Gavrilovic, Radmila Jankovic, Natasa Maksimovic, Rafael Stroggilos, Jerome Zoidakis, Sergi Castellví-Bel, Remond J. A. Fijneman, Milena Cavic
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: The standard treatment for locally advanced rectal cancer (LARC) is neoadjuvant chemoradiotherapy (nCRT). To select patients who would benefit the most from nCRT, there is a need for predictive biomarkers. The aim of this study was to e
Externí odkaz:
https://doaj.org/article/6fba8ca2e4e6468bb9faa382c9c3f5d9