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© Springer Nature Singapore Pte Ltd. 2019. Cardiovascular disease (CVD) is a major public health problem, particularly in the industrialised world, with diverse causes. Central to these underlying aetiologies is a progressive loss of functional card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::abcf07233164f99b36f413b403f022b0
https://hdl.handle.net/10453/141554
https://hdl.handle.net/10453/141554
Our laboratory has recently developed a novel three-dimensional in vitro model of the human heart, which we call the vascularized cardiac spheroid (VCS). These better recapitulate the human heart's cellular and extracellular microenvironment compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::edadc3c5b01bb567cc6087546e7d923a
https://hdl.handle.net/10453/140487
https://hdl.handle.net/10453/140487
Autor:
O'Neill, ES, Kaur, A, Bishop, DP, Shishmarev, D, Kuchel, PW, Grieve, SM, Figtree, GA, Renfrew, AK, Bonnitcha, PD, New, EJ
© 2017 American Chemical Society. Dense tumors are resistant to conventional chemotherapies due to the unique tumor microenvironment characterized by hypoxic regions that promote cellular dormancy. Bioreductive drugs that are activated in response t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::284a4527936528777599497ecec636ee
https://hdl.handle.net/10453/124487
https://hdl.handle.net/10453/124487
Spheroid cultures are among the most explored cellular biomaterials used in cardiovascular research, due to their improved integration of biochemical and physiological features of the heart in a defined architectural three-dimensional microenvironmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::7e6937908f5babf9cec549d2f55b1333
https://hdl.handle.net/10453/160846
https://hdl.handle.net/10453/160846
Autor:
Galougahi, KK, Liu, C-C, Gentile, C, Kok, C, Nunez, A, Garcia, A, Fry, NAS, Davies, MJ, Hawkins, CL, Rasmussen, HH, Figtree, GA
BACKGROUND: Glutathionylation of endothelial nitric oxide synthase (eNOS) "uncouples" the enzyme, switching its function from nitric oxide (NO) to O2(•-) generation. We examined whether this reversible redox modification plays a role in angiotensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::81464da14a986fe675a486c5c8062cbd
https://hdl.handle.net/10453/166573
https://hdl.handle.net/10453/166573
Publikováno v:
BJOG: An International Journal of Obstetrics & Gynaecology; Oct2015, Vol. 122 Issue 11, p1446-1455, 10p, 1 Diagram, 2 Charts, 1 Graph
Akademický článek
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Akademický článek
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Autor:
Bundgaard H, Liu CC, Garcia A, Hamilton EJ, Huang Y, Chia KK, Hunyor SN, Figtree GA, Rasmussen HH
Publikováno v:
Circulation; 12/21/2010, Vol. 122 Issue 25, p2699-2708, 10p