Zobrazeno 1 - 10 of 451 pro vyhledávání: '"Figler RA"'
1
Akademický článek
Human cardiovascular disease model predicts xanthine oxidase inhibitor cardiovascular risk.
Autor: Feaver RE; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Bowers MS; Horizon Therapeutics plc, Deerfield, Illinois, United States of America., Cole BK; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Hoang S; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Lawson MJ; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Taylor J; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., LaMoreaux BD; Horizon Therapeutics plc, Deerfield, Illinois, United States of America., Zhao L; Horizon Therapeutics plc, Deerfield, Illinois, United States of America., Henke BR; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Johns BA; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Nyborg AC; Horizon Therapeutics plc, Deerfield, Illinois, United States of America., Wamhoff BR; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America., Figler RA; HemoShear Therapeutics, Incorporated., Charlottesville, Virginia, United States of America.
Publikováno v: PloS one [PLoS One] 2023 Sep 08; Vol. 18 (9), pp. e0291330. Date of Electronic Publication: 2023 Sep 08 (Print Publication: 2023).
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2
Report
Genomic and biochemical analysis of repeatedly observed variants in DBT in individuals with maple syrup urine disease of Central American ancestry.
Autor: Billington CJ Jr; Children's National Rare Disease Institute, Washington, District of Columbia, USA.; Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA., Chapman KA; Children's National Rare Disease Institute, Washington, District of Columbia, USA., Leon E; Children's National Rare Disease Institute, Washington, District of Columbia, USA., Meltzer BW; Laboratory Medicine, Children's National Hospital, Washington, District of Columbia, USA., Berger SI; Children's National Rare Disease Institute, Washington, District of Columbia, USA., Olson M; HemoShear Therapeutics, Inc., Charlottesville, Virginia, USA., Figler RA; HemoShear Therapeutics, Inc., Charlottesville, Virginia, USA., Hoang SA; HemoShear Therapeutics, Inc., Charlottesville, Virginia, USA., Wanxing C; Georgetown University Hospital, Washington, District of Columbia, USA., Wamhoff BR; HemoShear Therapeutics, Inc., Charlottesville, Virginia, USA., Collado MS; HemoShear Therapeutics, Inc., Charlottesville, Virginia, USA., Cusmano-Ozog K; Department of Pathology, Stanford University Medical Center, Stanford, California, USA.
Publikováno v: American journal of medical genetics. Part A [Am J Med Genet A] 2022 Sep; Vol. 188 (9), pp. 2738-2749. Date of Electronic Publication: 2022 Jul 07.
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3
Akademický článek
A novel small molecule approach for the treatment of propionic and methylmalonic acidemias.
Autor: Armstrong AJ; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Collado MS; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Henke BR; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Olson MW; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Hoang SA; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Hamilton CA; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Pourtaheri TD; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Chapman KA; Children's National Rare Disease Institute, Washington, DC, USA., Summar MM; Children's National Rare Disease Institute, Washington, DC, USA., Johns BA; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Wamhoff BR; HemoShear Therapeutics, Inc., Charlottesville, VA, USA. Electronic address: wamhoff@hemoshear.com., Reardon JE; HemoShear Therapeutics, Inc., Charlottesville, VA, USA., Figler RA; HemoShear Therapeutics, Inc., Charlottesville, VA, USA.
Publikováno v: Molecular genetics and metabolism [Mol Genet Metab] 2021 May; Vol. 133 (1), pp. 71-82. Date of Electronic Publication: 2021 Mar 10.
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4
Akademický článek
Identification of 2,2-Dimethylbutanoic Acid (HST5040), a Clinical Development Candidate for the Treatment of Propionic Acidemia and Methylmalonic Acidemia.
Autor: Armstrong AJ; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Henke BR; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Collado MS; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Taylor JM; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Pourtaheri TD; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Dillberger JE; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Roper TD; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Wamhoff BR; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Olson MW; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Figler RA; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Hoang SA; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Reardon JE; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States., Johns BA; HemoShear Therapeutics Inc., 501 Locust Avenue, Charlottesville, Virginia 22902, United States.
Publikováno v: Journal of medicinal chemistry [J Med Chem] 2021 Apr 22; Vol. 64 (8), pp. 5037-5048. Date of Electronic Publication: 2021 Apr 13.
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5
Akademický článek
Validation of a multicellular tumor microenvironment system for modeling patient tumor biology and drug response.
Autor: Roller DG; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, MR6 Rm B526 345 Crispell Dr, PO Box 801318, Charlottesville, VA, 22908, USA., Hoang SA; HemoShear Therapeutics, Inc., 501 Locust Ave #301, Charlottesville, VA, 22902, USA., Rawls KD; HemoShear Therapeutics, Inc., 501 Locust Ave #301, Charlottesville, VA, 22902, USA., Owen KA; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, MR6 Rm B526 345 Crispell Dr, PO Box 801318, Charlottesville, VA, 22908, USA., Simmers MB; HemoShear Therapeutics, Inc., 501 Locust Ave #301, Charlottesville, VA, 22902, USA., Figler RA; HemoShear Therapeutics, Inc., 501 Locust Ave #301, Charlottesville, VA, 22902, USA., Wulfkuhle JD; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA., Petricoin EF; Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, USA., Wamhoff BR; HemoShear Therapeutics, Inc., 501 Locust Ave #301, Charlottesville, VA, 22902, USA. wamhoff@hemoshear.com., Gioeli D; Departments of Microbiology, Immunology, and Cancer Biology, University of Virginia, MR6 Rm B526 345 Crispell Dr, PO Box 801318, Charlottesville, VA, 22908, USA. dgioeli@virginia.edu.; Cancer Center Member, University of Virginia, Charlottesville, VA, USA. dgioeli@virginia.edu.
Publikováno v: Scientific reports [Sci Rep] 2021 Mar 10; Vol. 11 (1), pp. 5535. Date of Electronic Publication: 2021 Mar 10.
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6
Akademický článek
Ketohexokinase inhibition improves NASH by reducing fructose-induced steatosis and fibrogenesis.
Autor: Shepherd EL; Centre for Liver and Gastroenterology Research and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Saborano R; Centre for Liver and Gastroenterology Research and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Northall E; Centre for Liver and Gastroenterology Research and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK., Matsuda K; Takeda Pharmaceuticals Cardiovascular and Metabolic Drug Discovery Unit, Kanagawa, Japan., Ogino H; Takeda Pharmaceuticals Cardiovascular and Metabolic Drug Discovery Unit, Kanagawa, Japan., Yashiro H; Takeda Pharmaceuticals Gastroenterology Drug Discovery Unit, Cambridge, MA, USA., Pickens J; Takeda Pharmaceuticals Gastroenterology Drug Discovery Unit, Cambridge, MA, USA., Feaver RE; HemoShear Therapeutics, Charlottesville, VA, USA., Cole BK; HemoShear Therapeutics, Charlottesville, VA, USA., Hoang SA; HemoShear Therapeutics, Charlottesville, VA, USA., Lawson MJ; HemoShear Therapeutics, Charlottesville, VA, USA., Olson M; HemoShear Therapeutics, Charlottesville, VA, USA., Figler RA; HemoShear Therapeutics, Charlottesville, VA, USA., Reardon JE; HemoShear Therapeutics, Charlottesville, VA, USA., Nishigaki N; Takeda Pharmaceuticals Cardiovascular and Metabolic Drug Discovery Unit, Kanagawa, Japan., Wamhoff BR; HemoShear Therapeutics, Charlottesville, VA, USA., Günther UL; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Hirschfield G; Centre for Liver and Gastroenterology Research and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Toronto Centre for Liver Disease, University of Toronto, Toronto General Hospital, Toronto, Canada., Erion DM; Takeda Pharmaceuticals Gastroenterology Drug Discovery Unit, Cambridge, MA, USA., Lalor PF; Centre for Liver and Gastroenterology Research and National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.
Publikováno v: JHEP reports : innovation in hepatology [JHEP Rep] 2020 Nov 20; Vol. 3 (2), pp. 100217. Date of Electronic Publication: 2020 Nov 20 (Print Publication: 2021).
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7
Akademický článek
Biochemical and anaplerotic applications of in vitro models of propionic acidemia and methylmalonic acidemia using patient-derived primary hepatocytes.
Autor: Collado MS; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Armstrong AJ; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Olson M; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Hoang SA; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Day N; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Summar M; Children's National Rare Disease Institute, Washington, DC, USA., Chapman KA; Children's National Rare Disease Institute, Washington, DC, USA., Reardon J; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Figler RA; HemoShear Therapeutics, LLC, Charlottesville, VA, USA., Wamhoff BR; HemoShear Therapeutics, LLC, Charlottesville, VA, USA. Electronic address: wamhoff@hemoshear.com.
Publikováno v: Molecular genetics and metabolism [Mol Genet Metab] 2020 Jul; Vol. 130 (3), pp. 183-196. Date of Electronic Publication: 2020 May 11.
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8
Akademický článek
Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells.
Autor: Gioeli D; Departments of Microbiology, Immunology, and Cancer Biology, Virginia, USA. dgg3f@virginia.edu., Snow CJ, Simmers MB, Hoang SA, Figler RA, Allende JA, Roller DG, Parsons JT, Wulfkuhle JD, Petricoin EF, Bauer TW, Wamhoff BR
Publikováno v: Lab on a chip [Lab Chip] 2019 Mar 27; Vol. 19 (7), pp. 1193-1204.
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9
Akademický článek
CD39 expression by regulatory T cells participates in CD8+ T cell suppression during experimental Trypanosoma cruzi infection.
Autor: Araujo Furlan, Cintia L.1,2 (AUTHOR) claraujo@unc.edu.ar, Boccardo, Santiago1,2 (AUTHOR), Rodriguez, Constanza1,2 (AUTHOR), Mary, Verónica S.1,2 (AUTHOR), Gimenez, Camila M. S.1,2 (AUTHOR), Robson, Simon C.3 (AUTHOR), Gruppi, Adriana1,2 (AUTHOR), Montes, Carolina L.1,2 (AUTHOR), Acosta Rodríguez, Eva V.1,2 (AUTHOR) claraujo@unc.edu.ar
Publikováno v: PLoS Pathogens. 4/29/2024, Vol. 20 Issue 4, p1-30. 30p.
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10
Akademický článek
Liver Damage During Treatment with Reverse-Transcriptase Inhibitors in HIV Patients.
Autor: LUNGU, GIORGIANA NICOLETA1 lungugiorgiananicoleta@gmail.com, DIACONESCU, GHEORGHE IULIAN2,3, DUMITRESCU, FLORENTINA2,4, DOCEA, ANCA OANA5, MITRUT, RADU1, GIUBELAN, LUCIAN2,4, ZLATIAN, OVIDIU6,7, MITRUT, PAUL8,9
Publikováno v: Current Health Sciences Journal. Apr-Jun2024, Vol. 50 Issue 2, p181-197. 17p.
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