Výsledky vyhledávání - "Figl, Antonio"

Dissertation/ Thesis

Structure-Function Analysis of the β Subunit of Neuronal Nicotinic Acetylcholine Receptors

Autor: Figl, Antonio

Nicotinic receptors belong to the superfamily of ligand-gated ion channels. Since evidence was rapidly accumulating implicating the non-α subunits in ligand-binding events, we decided to investigate eventual contributions of the neuronal β subunit

Externí odkaz: https://thesis.library.caltech.edu/11901/1/figl-a-1996.pdf

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Mutations Linked to Autosomal Dominant Nocturnal Frontal Lobe Epilepsy Affect Allosteric Ca²⁺ Activation of the α4β2 Nicotinic Acetylcholine Receptor

Autor: Rodrigues-Pinguet, Nivalda O., Pinguet, Thierry J., Figl, Antonio, Lester, Henry A., Cohen, Bruce N.

Extracellular Ca²⁺ robustly potentiates the acetylcholine response of α4β2 nicotinic receptors. Rat orthologs of five mutations linked to autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)—α4(S252F), α4(S256L), α4(+L264), β2(V262L

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________38::c32bdcaf0b8448a0a74075ea4ae919d5
https://resolver.caltech.edu/CaltechAUTHORS:20200428-121436325

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Pharmacological similarities between native brain and heterologously expressed α4β2 nicotinic receptors

Autor: Shafaee, Navid, Houng, McCann, Truong, Anthony, Viseshakul, Nareerat, Figl, Antonio, Sandhu, Sumandeep, Forsayeth, John R, Dwoskin, Linda P, Crooks, Peter A, Cohen, Bruce N

1 We studied the pharmacological properties of native rat brain and heterologously expressed rat alpha4beta2 nicotinic receptors immunoprecipitated onto a fixed substrate with the anti-alpha4 antibody mAb 299. 2 Immunodepletion with the anti-beta2 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b46c2f479f2e29cf6165c6b576581da5
https://europepmc.org/articles/PMC1571746/

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Voltage-Jump Relaxation Kinetics for Wild-type and Chimeric β Subunits of Neuronal Nicotinic Receptors

Autor: Figl, Antonio, Labarca, Cesar, Davidson, Norman, Lester, Henry A., Cohen, Bruce N.

We have studied the voltage-jump relaxation currents for a series of neuronal nicotinic acetylcholine receptors resulting from the coexpression of wild-type and chimeric β4/β2 subunits with α3 subunits in Xenopus oocytes. With acetylcholine as the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od________38::44d8332e1ab2f91b24c991641787e242
https://resolver.caltech.edu/CaltechAUTHORS:20120208-075012754

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