Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Fiflis, David Nicholas"'
Autor:
Carlson-Stevermer, Jared, Das, Amritava, Abdeen, Amr, Fiflis, David Nicholas, Grindel, Benjamin Isaac, Akcan, Tugce, Alam, Tausif, Kleitzen, Heidi, Kohlenberg, Lucille, Goedland, Madelyn, Dombroe, Micah J, Saha, Krishanu
Gene correction of multiple alleles for compound heterozygous recessive or polygenic diseases is a promising therapeutic strategy. However, the targeting of multiple alleles using genome editors in a single cell could lead to mixed genotypes and adve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d922150943314a80e504b7b9333fa7
Autor:
Carlson-Stevemer, Jared, Das, Amritava, Fiflis, David Nicholas, Abdeen, Amr, Kleitzen, Heidi, Kohlenberg, Lucille, Goedland, Madelyn, Connor, Nadine, Saha, Krishanu
Genome editing has high potential to directly correct endogenous diseased alleles in the body for the treatment of many inherited disorders. While potential off-target effects and other safety concerns have been extensively studied, the efficacy of g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0559b0f4df970bfc6e455db1d47372