Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Fievos L, Christofi"'
Autor:
Reiner Schneider, Patrick Leven, Shilpashree Mallesh, Mona Breßer, Linda Schneider, Elvio Mazzotta, Paola Fadda, Tim Glowka, Tim O. Vilz, Philipp Lingohr, Jörg C. Kalff, Fievos L. Christofi, Sven Wehner
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
IL1R1-signaling triggers enteric glia reactivity, resulting in enteric gliosis, macrophage activation and the development of postoperative ileus.
Externí odkaz:
https://doaj.org/article/057fccde179c48a2a708045aac6df548
Autor:
Elvio Mazzotta, Egina Criseida Villalobos-Hernandez, Juan Fiorda-Diaz, Alan Harzman, Fievos L. Christofi
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Postoperative ileus (POI) and postoperative gastrointestinal tract dysfunction (POGD) are well-known complications affecting patients undergoing intestinal surgery. GI symptoms include nausea, vomiting, pain, abdominal distention, bloating, and const
Externí odkaz:
https://doaj.org/article/23d4beda239b45bba308bc29485bb457
Autor:
Andromeda Liñán-Rico, Fernando Ochoa-Cortes, Alix Zuleta-Alarcon, Mazin Alhaj, Esmerina Tili, Josh Enneking, Alan Harzman, Iveta Grants, Sergio Bergese, Fievos L. Christofi
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Background: Enterochromaffin cells (EC) synthesize and release 5-HT and ATP to trigger or modulate gut neural reflexes and transmit information about visceral/pain sensation. Alterations in 5-HT signaling mechanisms may contribute to the pathogenesis
Externí odkaz:
https://doaj.org/article/65cdeed9d3984965b75053f629345a19
Publikováno v:
American Journal of Biomedical Science & Research. 8:535-538
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51188c3c247a033bfdf5d3f7c4693915
https://doi.org/10.34297/ajbsr.2020.08.001335
https://doi.org/10.34297/ajbsr.2020.08.001335
Autor:
Reiner, Schneider, Patrick, Leven, Shilpashree, Mallesh, Mona, Breßer, Linda, Schneider, Elvio, Mazzotta, Paola, Fadda, Tim, Glowka, Tim O, Vilz, Philipp, Lingohr, Jörg C, Kalff, Fievos L, Christofi, Sven, Wehner
Publikováno v:
Communications biology. 5(1)
Muscularis Externa Macrophages (ME-Macs) and enteric glial cells (EGCs) are closely associated cell types in the bowel wall, and important interactions are thought to occur between them during intestinal inflammation. They are involved in developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1c1d24cdc0ccdc9d22956a90b6f80627
https://pubmed.ncbi.nlm.nih.gov/35962064
https://pubmed.ncbi.nlm.nih.gov/35962064
Autor:
Egina C. Villalobos-Hernandez, Fernando Ochoa-Cortes, Elvio Mazzotta, Samhita Chaudhuri, Suren Soghomonyan, Juan Fiorda Diaz, Iveta Grants, Alan Harzman, Fievos L. Christofi
Publikováno v:
Gastroenterology. 162:S-37
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de31b6820d9fcba57f33dbb75c292f9d
https://doi.org/10.1016/s0016-5085(22)60092-1
https://doi.org/10.1016/s0016-5085(22)60092-1
Autor:
Alan Harzman, Fievos L. Christofi, Juan Fiorda-Diaz, Elvio Mazzotta, Egina Criseida Villalobos-Hernandez
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Postoperative ileus (POI) and postoperative gastrointestinal tract dysfunction (POGD) are well-known complications affecting patients undergoing intestinal surgery. GI symptoms include nausea, vomiting, pain, abdominal distention, bloating, and const
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cb2baa5f7af45dd3fadd947100f6195
http://europepmc.org/articles/PMC7774512
http://europepmc.org/articles/PMC7774512
Autor:
Iveta Grants, Elvio Mazzotta, Fievos L. Christofi, Adam J. Moeser, Brian D. Gulbransen, Alfred J. Robison, Natalia Duque-Wilckens, Nidia Maradiaga, Jonathon L. McClain
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Early-life adversity contributes to the development of functional bowel disorders later in life through unresolved mechanisms. Here, we tested the hypothesis that early-life adversity alters anatomical and functional interactions between mast cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cda251f103acfaffe590f580274f516
https://pubmed.ncbi.nlm.nih.gov/32996781
https://pubmed.ncbi.nlm.nih.gov/32996781
Autor:
Fievos L. Christofi, Adil E. Bharucha
Publikováno v:
Current Opinion in Pharmacology. 37:iv-viii
While we have made great strides in developing new therapeutic strategies to treat certain GI diseases such as hepatitis C, much more is necessary! There is a dire need for new therapies for complex diseases such as motility disorders, IBD, obesity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66feeb9f7c87e771c4720ba46e3832ee
https://doi.org/10.1016/j.coph.2017.11.011
https://doi.org/10.1016/j.coph.2017.11.011
Autor:
Mahmoud Abdel-Rasoul, Jeffrey Yu, Fievos L. Christofi, Suren Soghomonyan, Victor Davila, Alix Zuleta-Alarcon, Razvan Arsenescu, Sergio D. Bergese, Iveta Grants, Cheng Zhang, Emmett E. Whitaker, Nicoleta Stoicea
Publikováno v:
Digestive Diseases and Sciences. 62:2728-2743
Clopidogrel is an irreversible antagonist of P2Y12 receptors (P2Y12Rs) used as an antiplatelet drug to reduce risk of thrombosis. P2Y12Rs are expressed in gastrointestinal (GI) tract where they might regulate GI function. To evaluate if blockade of P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a8bb4bad298209732f7b57986f4d6cb
https://doi.org/10.1007/s10620-017-4707-7
https://doi.org/10.1007/s10620-017-4707-7