Drug reformulation for a neglected disease. The NANOHAT project to develop a safer more effective sleeping sickness drug.

Autor: Sanderson L; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., da Silva M; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Sekhar GN; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Brown RC; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Burrell-Saward H; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Fidanboylu M; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Liu B; King's College London, Department of Diabetes, School of Life Course Sciences, Faculty of Life Sciences & Medicine, London, United Kingdom., Dailey LA; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Dreiss CA; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Lorenz C; King's College London, Theory & Simulation of Condensed Matter Group, Department of Physics, Strand, London, United Kingdom., Christie M; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom., Persaud SJ; King's College London, Department of Diabetes, School of Life Course Sciences, Faculty of Life Sciences & Medicine, London, United Kingdom., Yardley V; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Croft SL; Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Valero M; Physical Chemistry Department, Faculty of Pharmacy, University of Salamanca, Salamanca, Spain., Thomas SA; King's College London, Institute of Pharmaceutical Science, Franklin-Wilkins Building, Stamford Street, London, United Kingdom.

Publikováno v: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Apr 15; Vol. 15 (4), pp. e0009276. Date of Electronic Publication: 2021 Apr 15 (Print Publication: 2021).

Reduced expression of fukutin related protein in mice results in a model for fukutin related protein associated muscular dystrophies.

Autor: Ackroyd MR, Skordis L, Kaluarachchi M, Godwin J, Prior S, Fidanboylu M, Piercy RJ, Muntoni F, Brown SC, Ackroyd, M R, Skordis, L, Kaluarachchi, M, Godwin, J, Prior, S, Fidanboylu, M, Piercy, R J, Muntoni, F, Brown, S C

Publikováno v: Brain: A Journal of Neurology; Feb2009, Vol. 132 Issue 2, p439-451, 13p

The transporter and permeability interactions of asymmetric dimethylarginine (ADMA) and L-arginine with the human blood-brain barrier in vitro.

Autor: Watson CP; King's College London, Institute of Pharmaceutical Science, Waterloo, London, UK., Pazarentzos E; Imperial College London, Experimental Medicine and Toxicology Section, Division of Experimental Medicine, London, UK., Fidanboylu M; King's College London, Institute of Pharmaceutical Science, Waterloo, London, UK., Padilla B; King's College London, Institute of Pharmaceutical Science, Waterloo, London, UK., Brown R; King's College London, Institute of Pharmaceutical Science, Waterloo, London, UK., Thomas SA; King's College London, Institute of Pharmaceutical Science, Waterloo, London, UK. Electronic address: sarah.thomas@kcl.ac.uk.

Publikováno v: Brain research [Brain Res] 2016 Oct 01; Vol. 1648 (Pt A), pp. 232-242. Date of Electronic Publication: 2016 Jul 16.

Delivery of antihuman African trypanosomiasis drugs across the blood-brain and blood-CSF barriers.

Autor: Sekhar GN; King's College London, Institute of Pharmaceutical Sciences, London, United Kingdom., Watson CP; King's College London, Institute of Pharmaceutical Sciences, London, United Kingdom., Fidanboylu M; King's College London, Institute of Pharmaceutical Sciences, London, United Kingdom., Sanderson L; King's College London, Institute of Pharmaceutical Sciences, London, United Kingdom., Thomas SA; King's College London, Institute of Pharmaceutical Sciences, London, United Kingdom. Electronic address: sarah.thomas@kcl.ac.uk.

Publikováno v: Advances in pharmacology (San Diego, Calif.) [Adv Pharmacol] 2014; Vol. 71, pp. 245-75. Date of Electronic Publication: 2014 Aug 22.

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents.

Autor: Lee B; Department of Molecular and Cellular Medicine, Texas A&M College of Medicine, College Station, Texas 77843, USA., Clarke D, Al Ahmad A, Kahle M, Parham C, Auckland L, Shaw C, Fidanboylu M, Orr AW, Ogunshola O, Fertala A, Thomas SA, Bix GJ

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2011 Aug; Vol. 121 (8), pp. 3005-23. Date of Electronic Publication: 2011 Jul 11.