Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Fibroblasts/drug effects"'
Autor:
Omid Savabi, Farahnaz Nejatidanesh, Morteza Sharifi, Mohammadjavad Shirani, Alireza Valanezhad, Ikuya Watanabe, Batool Hashemi Beni, Mohammad Khodaei
Publikováno v:
Dental Research Journal, Vol 21, Iss 1, Pp 53-53 (2024)
Background: This study aimed to evaluate the effect of new computer-aided design/computer-aided manufacturing all-ceramic materials on the viability and adhesion properties of human gingival fibroblasts (HGFs). Materials and Methods: In this experime
Externí odkaz:
https://doaj.org/article/9b8c4c0dca924018999f53729e484be6
Autor:
Ge, Xiangyu, Frank-Bertoncelj, Mojca, Klein, Kerstin, McGovern, Amanda, Kuret, Tadeja, Houtman, Miranda, Burja, Blaž, Micheroli, Raphael, Shi, Chenfu, Marks, Miriam, Filer, Andrew, Buckley, Christopher D, Orozco, Gisela, Distler, Oliver, Morris, Andrew P, Martin, Paul, Eyre, Stephen, Ospelt, Caroline
Publikováno v:
Ge, X, Frank-Bertoncelj, M, Klein, K, McGovern, A, Kuret, T, Houtman, M, Burja, B, Micheroli, R, Shi, C, Marks, M, Filer, A, Buckley, C D, Orozco, G, Distler, O, Morris, A P, Martin, P, Eyre, S & Ospelt, C 2021, ' Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability ', Genome Biology, vol. 22, no. 1, 247, pp. 247 . https://doi.org/10.1186/s13059-021-02460-6
Genome Biology, Vol 22, Iss 1, Pp 1-39 (2021)
Genome Biology
Genome Biology, Vol 22, Iss 1, Pp 1-39 (2021)
Genome Biology
Background Genome-wide association studies have reported more than 100 risk loci for rheumatoid arthritis (RA). These loci are shown to be enriched in immune cell-specific enhancers, but the analysis so far has excluded stromal cells, such as synovia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0674df2310dba62eb17625de0edb67
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Nano-hydroxyapatite has been used as an oral care ingredient, being incorporated in several products for the treatment of dental hypersensitivity and enamel remineralisation. Despite its promising results, regulatory and safety concerns have been dis
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics, Vol. 140 (2019) pp. 100-108
Wound healing, when compromised, may be guided by biological cues such as Arg-Gly-Asp (RGD), a peptide known to induce cell adhesion and migration, eventually combined with adapted nanocarriers. Three different formulations were prepared and investig
Autor:
Patrick S. Asmawidjaja, E. M. Colin, Johanna M. W. Hazes, Adriana M. C. Mus, Erik Lubberts, Claudia González-Leal, Wendy Dankers, Nadine Davelaar
Publikováno v:
Arthritis research & therapy, 20(1). BioMed Central
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Arthritis Research & Therapy, 20:212. BioMed Central Ltd.
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-10 (2018)
Arthritis Research & Therapy, 20:212. BioMed Central Ltd.
Background Despite recent improvements in the treatment of rheumatoid arthritis (RA), an insufficient treatment response and the development of treatment resistance in many patients illustrates the need for new therapeutic strategies. Chronic synovia
Publikováno v:
Sharif, R, Sejersen, H, Frank, G, Hjortdal, J & Karamichos, D 2018, ' Effects of collagen cross-linking on the keratoconus metabolic network ', Eye, vol. 32, no. 7, pp. 1271-1281 . https://doi.org/10.1038/s41433-018-0075-6
PURPOSE: Keratoconus (KC) is a multifactorial, ectatic corneal disease. Metabolic changes in the corneal stroma with alterations in collagen fibril stability, oxidative stress, and urea cycle, have previously been reported as key players in KC pathob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09631480b2f264aeb776a26721c9f2ff
https://pure.au.dk/portal/da/publications/effects-of-collagen-crosslinking-on-the-keratoconus-metabolic-network(12bfad82-8c7c-4bc3-88ab-43448965c273).html
https://pure.au.dk/portal/da/publications/effects-of-collagen-crosslinking-on-the-keratoconus-metabolic-network(12bfad82-8c7c-4bc3-88ab-43448965c273).html
Autor:
Mathieu Auzias, Kentaro Yamaguchi, Frédéric Schmitt, Petr Štěpnička, Georg Süss-Fink, Yoshihisa Sei, Lucienne Juillerat-Jeanneret, Bruno Therrien
Publikováno v:
Journal of Biological Inorganic Chemistry, vol. 14, no. 5, pp. 693-701
Diruthenium tetracarbonyl complexes of the type [Ru2 (CO)4(μ2-η2-O2CR)2L2] containing a Ru–Ru backbone with four equatorial carbonyl ligands, two carboxylato bridges, and two axial two-electron ligands in a sawhorse-like geometry have been synthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094070ade7b16f4bcf793b5fceb1e46e
http://doc.rero.ch/record/317633/files/775_2009_Article_482.pdf
http://doc.rero.ch/record/317633/files/775_2009_Article_482.pdf
Autor:
Thomas Sauter, Eivind Valen Egeland, Kjetil Nordbø Jørgensen, Marco Vincent Haselager, Kotryna Seip, Olav Engebraaten, Gunhild Mari Mælandsmo, Mads H. Haugen, Philippe Lucarelli, Lina Prasmickaite, Marco Albrecht
Publikováno v:
Cancer Letters
Cancer letters. Ireland (2018).
Cancer letters, 439, 1-13. Elsevier Ireland Ltd
Cancer letters. Ireland (2018).
Cancer letters, 439, 1-13. Elsevier Ireland Ltd
Cancer cells' phenotypic plasticity, promoted by stromal cells, contributes to intra-tumoral heterogeneity and affects response to therapy. We have disclosed an association between fibroblast-stimulated phenotype switching and resistance to the clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fbcc4dfdc14a08c4b4006f746f2834f
https://hdl.handle.net/10037/18712
https://hdl.handle.net/10037/18712
Autor:
Liao, Chunyan, Ashley, Neil, Diot, Alan, Morten, Karl, Phadwal, Kanchan, Williams, Andrew, Fearnley, Ian, Rosser, Lyndon, Lowndes, Jo, Fratter, Carl, Ferguson, David J.P., Vay, Laura, Quaghebeur, Gerardine, Moroni, Isabella, Bianchi, Stefania, Lamperti, Costanza, Downes, Susan M., Sitarz, Kamil S., Flannery, Padraig J., Carver, Janet, Dombi, Eszter, East, Daniel, Laura, Matilde, Reilly, Mary M., Mortiboys, Heather, Prevo, Remko, Campanella, Michelangelo, Daniels, Matthew J., Zeviani, Massimo, Yu-Wai-Man, Patrick, Simon, Anna Katharina, Votruba, Marcela, Poulton, Joanna
Publikováno v:
Neurology
Liao, C, Ashley, N, Diot, A, Morten, K, Phadwal, K, Williams, A, Fearnley, I, Rosser, L, Lowndes, J, Fratter, C, Ferguson, D J P, Vay, L, Quaghebeur, G, Moroni, I, Bianchi, S, Lamperti, C, Downes, S M, Sitarz, K S, Flannery, P J, Carver, J, Dombi, E, East, D, Laura, M, Reilly, M M, Mortiboys, H, Prevo, R, Campanella, M, Daniels, M J, Zeviani, M, Yu-Wai-Man, P, Simon, A K, Votruba, M & Poulton, J 2017, ' Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations ', Neurology, vol. 88, no. 2, pp. 131-142 . https://doi.org/10.1212/WNL.0000000000003491
Digital.CSIC. Repositorio Institucional del CSIC
instname
Liao, C, Ashley, N, Diot, A, Morten, K, Phadwal, K, Williams, A, Fearnley, I, Rosser, L, Lowndes, J, Fratter, C, Ferguson, D J P, Vay, L, Quaghebeur, G, Moroni, I, Bianchi, S, Lamperti, C, Downes, S M, Sitarz, K S, Flannery, P J, Carver, J, Dombi, E, East, D, Laura, M, Reilly, M M, Mortiboys, H, Prevo, R, Campanella, M, Daniels, M J, Zeviani, M, Yu-Wai-Man, P, Simon, A K, Votruba, M & Poulton, J 2017, ' Dysregulated mitophagy and mitochondrial organization in optic atrophy due to OPA1 mutations ', Neurology, vol. 88, no. 2, pp. 131-142 . https://doi.org/10.1212/WNL.0000000000003491
Digital.CSIC. Repositorio Institucional del CSIC
instname
© 2016 The Author(s).
[Objective]: To investigate mitophagy in 5 patients with severe dominantly inherited optic atrophy (DOA), caused by depletion of OPA1 (a protein that is essential for mitochondrial fusion), compared with healthy controls.
[Objective]: To investigate mitophagy in 5 patients with severe dominantly inherited optic atrophy (DOA), caused by depletion of OPA1 (a protein that is essential for mitochondrial fusion), compared with healthy controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::405f90410b7c65c0cc88235b04994e56
Publikováno v:
Biomolecules
Volume 9
Issue 1
Biomolecules, Vol 9, Iss 1, p 4 (2018)
Volume 9
Issue 1
Biomolecules, Vol 9, Iss 1, p 4 (2018)
Nitric oxide (NO) is an endogenously produced molecule that has been implicated in several wound healing mechanisms. Its topical delivery may improve healing in acute or chronic wounds. In this study an antimicrobial peptide was synthesized which sel