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Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.

Autor: Su W; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; Ningbo First Hospital, Ningbo, China., Zheng X; Wenzhou Medical University, Wenzhou, China., Zhou H; Ningbo First Hospital, Ningbo, China., Yang S; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: yangshengwu188@sina.com., Zhu X; The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China. Electronic address: zhuxiongbai392@sina.com.

Publikováno v: Molecular immunology [Mol Immunol] 2023 Jul; Vol. 159, pp. 46-57. Date of Electronic Publication: 2023 Jun 02.

Effects of FGFR2b-ligand signaling on pancreatic branching morphogenesis and postnatal islet function.

Autor: Jin LL; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China., Yin YL; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China., Li FW; International Collaborative Center On Growth Factor Research, and School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Zhou YM; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China., Chen W; Institute of Life Sciences, Wenzhou University, Wenzhou, China., Tian Y; International Collaborative Center On Growth Factor Research, and School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Feng X; International Collaborative Center On Growth Factor Research, and School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China., Xu Y; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China., Chen PF; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China., Zhang JS; The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou, China. Zhang_jinsan@wmu.edu.cn., Xu HJ; National Clinical Research Center for Ocular Disease, School of Ophthalmology and Optometry, Eye Hospital, Wenzhou Medical University, 270 West Xueyuan Road, Wenzhou, 325027, Zhejiang, China. xhj114485@wmu.edu.cn.; International Collaborative Center On Growth Factor Research, and School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China. xhj114485@wmu.edu.cn.

Publikováno v: Journal of molecular histology [J Mol Histol] 2024 Dec 18; Vol. 56 (1), pp. 45. Date of Electronic Publication: 2024 Dec 18.

RNA-Seq explores the functional role of the fibroblast growth factor 10 gene in bovine adipocytes differentiation

Autor: Nurgulsim Kaster, Rajwali Khan, Ijaz Ahmad, Kazhgaliyev Nurlybay Zhigerbayevich, Imbay Seisembay, Akhmetbekov Nurbolat, Shaikenova Kymbat Hamitovna, Omarova Karlygash Mirambekovna, Makhanbetova Aizhan Bekbolatovna, Tlegen Garipovich Amangaliyev, Ateikhan Bolatbek, Titanov Zhanat Yeginbaevich, Shakoor Ahmad, Zan Linsen, Begenova Ainagul Baibolsynovna

Publikováno v: Animal Bioscience, Vol 37, Iss 5, Pp 929-943 (2024)

Objective The present study was executed to explore the molecular mechanism of fibroblast growth factor 10 (FGF10) gene in bovine adipogenesis. Methods The bovine FGF10 gene was overexpressed through Ad-FGF10 or inhibited through siFGF10 and their ne

Externí odkaz: https://doaj.org/article/905b8bd6131a403b8847964e77c954ca

Fibroblast growth factor 10 reverses cigarette smoke- and elastase-induced emphysema and pulmonary hypertension in mice.

Autor: Hadzic S; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Wu CY; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Gredic M; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Pak O; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Loku E; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Kraut S; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Kojonazarov B; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Institute for Lung Health (ILH), Justus-Liebig-University, Giessen, Germany., Wilhelm J; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Institute for Lung Health (ILH), Justus-Liebig-University, Giessen, Germany., Brosien M; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Bednorz M; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Seimetz M; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Günther A; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Kosanovic D; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia., Sommer N; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Warburton D; Children's Hospital Los Angeles, Los Angeles, CA, USA.; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Li X; School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, P.R. China., Grimminger F; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Ghofrani HA; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Schermuly RT; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany., Seeger W; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Max-Planck Institute for Heart and Lung Research, Bad Nauheim, Germany., El Agha E; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; Institute for Lung Health (ILH), Justus-Liebig-University, Giessen, Germany., Bellusci S; Oujiang Laboratory (Zheijiang Laboratory for Regenerative Medicine, Vision and Brain Health), School of Pharmaceutical Science, Wenzhou Medical University, Wenzhou, P.R. China.; Laboratory of Extracellular Matrix Remodelling, Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany.; S. Bellusci and N. Weissmann contributed equally to this article as lead authors and supervised the work., Weissmann N; Excellence Cluster Cardio-Pulmonary Institute (CPI), Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig-University, Giessen, Germany norbert.weissmann@innere.med.uni-giessen.de.; S. Bellusci and N. Weissmann contributed equally to this article as lead authors and supervised the work.

Publikováno v: The European respiratory journal [Eur Respir J] 2023 Nov 09; Vol. 62 (5). Date of Electronic Publication: 2023 Nov 09 (Print Publication: 2023).