Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Fiachra B. Bolger"'
Autor:
John P. Lowry, Fiachra B. Bolger
Publikováno v:
Sensors, Vol 5, Iss 11, Pp 473-487 (2005)
In this communication we review selected experiments involving the use ofcarbon paste electrodes (CPEs) to monitor and measure brain tissue O2 levels in awakefreely-moving animals. Simultaneous measurements of rCBF were performed using the H2clearanc
Externí odkaz:
https://doaj.org/article/3738b7e0d0dc40358ceb979d2e3d6141
Publikováno v:
Analytica Chimica Acta. 1224:340205
A polymer/enzyme composite biosensor for monitoring neurochemical glutamate was performance optimised in vitro for sensitivity, selectivity and stability. This first generation Pt/glutamate oxidase-based sensor displayed appropriate sensitivity (90.4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77d90564f463eb37adb945f2cddc1e8b
https://doi.org/10.1016/j.aca.2022.340205
https://doi.org/10.1016/j.aca.2022.340205
Autor:
Saidhbhe L. O'Riordan, Michelle M. Doran, Fiachra B. Bolger, Michelle Sands, John P. Lowry, John Kelly, Gama Theophile Gnahore
Publikováno v:
Analytical methods : advancing methods and applications. 12(19)
Oxygen is of critical importance to tissue viability and there is increasing demand for its reliable real-time clinical monitoring in order to prevent, diagnose, and treat several pathological disorders, including hypoxia, stroke and reperfusion inju
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370bc43561338d9441fbed028c4a8c2c
https://pubmed.ncbi.nlm.nih.gov/32930234
https://pubmed.ncbi.nlm.nih.gov/32930234
Publikováno v:
Electroanalysis. 31:129-136
A choline biosensor was characterised in detail to determine the effects of physiologically relevant parameters on the ability of the sensor to reliably detect neurochemical changes in choline. This first generation Pt-based polymer enzyme composite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5a8a2a54dc3a0a189479a3c861aa5c
https://doi.org/10.1002/elan.201800642
https://doi.org/10.1002/elan.201800642
Autor:
Niall J. Finnerty, Fiachra B. Bolger
Publikováno v:
The Analyst. 143:3124-3133
Attempts to develop miniaturised pH electrodes for in vivo monitoring have received much attention in recent years. Continuous real-time pH measurements may be predictive of potentially dangerous deviations in metabolic events that could improve pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42b313844011108e960889b85dc3002e
https://doi.org/10.1039/c8an00631h
https://doi.org/10.1039/c8an00631h
Publikováno v:
The Analyst. 140:3738-3745
A first generation Pt-based polymer enzyme composite biosensor developed for real-time neurochemical monitoring was characterised in vivo for sensitive and selective detection of choline. Confirmation that the sensor responds to changes in extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32480a0bde914ea51196dc29df7552c7
https://doi.org/10.1039/c4an02027h
https://doi.org/10.1039/c4an02027h
Here we describe the development of a first generation biosensor for the detection of brain extracellular choline, investigating important considerations for in-vivo monitoring such as sensor sensitivity, O 2 interference and selectivity. Extensive o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e994e136a18ddf858ffea3be7c98c1d4
http://mural.maynoothuniversity.ie/11613/
http://mural.maynoothuniversity.ie/11613/
Autor:
Fiachra B. Bolger, Niall J. Finnerty
Publikováno v:
Bioelectrochemistry (Amsterdam, Netherlands). 119
Acute limb ischaemia is caused by compromised tissue perfusion and requires immediate attention to reduce the occurrence of secondary complications that could lead to amputation or death. To address this, we have developed a novel platinum (Pt)-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6b945346746b9a3fb18486aa52a064
https://pubmed.ncbi.nlm.nih.gov/28972912
https://pubmed.ncbi.nlm.nih.gov/28972912
Publikováno v:
ACS Chemical Neuroscience. 4:825-831
Glucose, O2, and nitric oxide (NO) were monitored in real time in the prefrontal cortex of freely moving animals using microelectrochemical sensors following phencyclidine (PCP) administration. Injection of saline controls produced a decrease in gluc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b3dd64aa22597b9e4da6878c77294e
https://doi.org/10.1021/cn4000567
https://doi.org/10.1021/cn4000567
Publikováno v:
Journal of Computational Neuroscience. 27:391-414
An integrative, systems approach to the modelling of brain energy metabolism is presented. Mechanisms such as glutamate cycling between neurons and astrocytes and glycogen storage in astrocytes have been implemented. A unique feature of the model is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0030d87b4f2225293c4b19a3ba2e38e8
https://doi.org/10.1007/s10827-009-0152-8
https://doi.org/10.1007/s10827-009-0152-8