IL-1β induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis

Autor: Sparre, T, Bjerre-Christensen, Ulla, Mose Larsen, P, Fey, S J, Wrzesinski, K, Roepstorff, P, Mandrup-Poulsen, Thomas, Pociot, Flemming Michael, Karlsen, Ellen Margrethe, Nerup, Jacob, Wrzesinski, Krzysztof

Publikováno v: Sparre, T, Bjerre-Christensen, U, Mose Larsen, P, Fey, S J, Wrzesinski, K, Roepstorff, P, Mandrup-Poulsen, T, Pociot, F M, Karlsen, E M, Nerup, J & Wrzesinski, K 2002, ' IL-1beta induced protein changes in diabetes prone BB rat islets of Langerhans identified by proteome analysis ', Diabetologia, vol. 45, no. 11, pp. 1550-61 . https://doi.org/10.1007/s00125-002-0953-z

Aims/hypothesis. Type I (insulin-dependent) diabetes mellitus is characterized by selective destruction of the insulin producing beta cells. Interleukin-1β (IL-1β) modulates the beta-cell function, protein synthesis, energy production and causes ap

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::129f3a71ffa08affef0e4abead466ba1
https://doi.org/10.1007/s00125-002-0953-z

Determination of acute lethal and chronic lethal dose thresholds of valproic acid using 3D spheroids constructed from the immortal human hepatocyte cell line HepG2/C3A

Autor: Fey, S. J., Wrzesinski, K.

Publikováno v: Fey, S J & Wrzesinski, K 2013, Determination of acute lethal and chronic lethal dose thresholds of valproic acid using 3D spheroids constructed from the immortal human hepatocyte cell line HepG2/C3A . in A Boucher (ed.), Valproic Acid : Pharmacology, Mechanisms of Action and Clinical Implications . Nova Science Publishers, pp. 141-165 . < http://www.scopus.com/inward/record.url?eid=2-s2.0-84891981522&partnerID=40&md5=51f161471a44133c487beaf1a17ac9a5 >

Valproic acid (VPA) is a broad-spectrum antiepileptic drug that is now used commonly for several other neurological and psychiatric indications. While VPA is usually well tolerated, on rare occasions, it has been associated with severe, and sometimes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::273f1cbfcd52890330359d44bc896f6e
https://portal.findresearcher.sdu.dk/da/publications/da353232-4642-4ef4-b29b-41e37235387c

Phytochemicals - Bioactivities and Impact on Health:Assessment of the Antidiabetic Potential of an Aqueous Extract of Honeybush (Cyclopia intermedia) in Streptozotocin and Obese Insulin Resistant Wistar Rats

Autor: Muller, C.J.F., Joubert, E., Gabuza, K., de Beer, D., Fey, S. J., Louw, J.

Publikováno v: Muller, C J F, Joubert, E, Gabuza, K, de Beer, D, Fey, S J & Louw, J 2011, Phytochemicals-Bioactivities and Impact on Health : Assessment of the Antidiabetic Potential of an Aqueous Extract of Honeybush (Cyclopia intermedia) in Streptozotocin and Obese Insulin Resistant Wistar Rats . vol. 13, 1 edn, InTech-Open Access Publisher . < http://www.intechopen.com/articles/show/title/assessment-of-the-antidiabetic-potential-of-an-aqueous-extract-of-honeybush-cyclopia-intermedia-in-s >

It has been estimated that diabetes will affect 439 million adults by 2030, with the major increase occurring in developing countries (Shaw et al., 2010). It is projected that it will rank as the 9th leading cause of death in low-income countries (Ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::de25cb455a7e5cf9d922f94dcca56273
https://portal.findresearcher.sdu.dk/da/publications/d5255c61-7bee-4dc0-b1b7-d0ca7b031191

Anti-Diabetic Extract Of Honeybush

Autor: Larsen, P. M., Fey, S. J., Louw, J., Joubert, L.

Publikováno v: Larsen, P M, Fey, S J, Louw, J & Joubert, L, Anti-Diabetic Extract Of Honeybush .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3062::58713ae7f33eceda98a310583fc3d342
https://portal.findresearcher.sdu.dk/da/publications/487cf51b-1311-4847-a4c1-761d962f518d

Bioreactor For Cell And Tissue Culture

Autor: Fey, S. J., Larsen, P. M.

Publikováno v: Fey, S J & Larsen, P M, Bioreactor For Cell And Tissue Culture, Patent No. Europe 2006828762, 2008 .
Fey, S J & Larsen, P M, Bioreactor For Cell And Tissue Culture, Patent No. WO/2007/076865 .
Fey, S J & Larsen, P M, Bioreactor For Cell And Tissue Culture, Patent No. Japan 2008547853, 2008 .
Fey, S J & Larsen, P M, Bioreactor For Cell And Tissue Culture, Patent No. USA 12159154, 2009 .
Fey, S J & Larsen, P M, Bioreactor For Cell And Tissue Culture, Patent No. China 200680052253.7, 2008 .

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::20af3e4cd9c6ec673fcc196081378219
https://portal.findresearcher.sdu.dk/da/publications/74880c98-7fab-4542-950b-e872396de362