Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma

Autor: Onken, Michael D., Noda, Sarah E., Kaltenbronn, Kevin M., Frankfater, Cheryl, Makepeace, Carol M., Fettig, Nikki, Piggott, Kisha D., Custer, Philip L., Ippolito, Joseph E., Blumer, Kendall J.

Publikováno v: In Journal of Biological Chemistry January 2022 298(1)

In vivo quantitative assessment of therapeutic response to bortezomib therapy in disseminated animal models of multiple myeloma with [¹⁸F]FDG and [⁶⁴Cu]Cu-LLP2A PET.

Autor: Ghai, Anchal¹ (AUTHOR), Fettig, Nikki¹ (AUTHOR), Fontana, Francesca² (AUTHOR), DiPersio, John³ (AUTHOR), Rettig, Mike³ (AUTHOR), Neal, Julie O.³ (AUTHOR), Achilefu, Samuel^1,4,5 (AUTHOR), Shoghi, Kooresh I.¹ (AUTHOR), Shokeen, Monica^1,4 (AUTHOR) shokeenm@wustl.edu

Publikováno v: EJNMMI Research. 9/29/2021, Vol. 11 Issue 1, p1-12. 12p.

Additional file 1 of In vivo quantitative assessment of therapeutic response to bortezomib therapy in disseminated animal models of multiple myeloma with [18F]FDG and [64Cu]Cu-LLP2A PET

Autor: Ghai, Anchal, Fettig, Nikki, Fontana, Francesca, DiPersio, John, Rettig, Mike, Neal, Julie O., Achilefu, Samuel, Shoghi, Kooresh I., Shokeen, Monica

Additional file1. Supplementary Fig S1: (a) Radio-HPLC chromatogram of [64Cu]Cu-LLP2A showing > 99% of radiolabeled product at the retention time of 5.6 min. (b) UV-visible spectrum showing the LLP2A peak at the same retention time as that of radiola

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Evaluation of Copanlisib in Combination with Eribulin in Triple-negative Breast Cancer Patient-derived Xenograft Models.

Autor: Guo Z; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Luo J; Division of Public Health Science, Siteman Cancer Center Biostatistics Core, Washington University School of Medicine, St. Louis, Missouri., Mashl RJ; Department of Medicine, McDonnell Genome Institute, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri., Hoog J; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Maiti P; Mallinckrodt Institute of Radiology, St. Louis, Missouri., Fettig N; Mallinckrodt Institute of Radiology, St. Louis, Missouri., Davies SR; Department of Surgery, Washington University School of Medicine, St. Louis, Missouri., Aft R; Department of Surgery, Washington University School of Medicine, St. Louis, Missouri., Held JM; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Govindan R; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., Ding L; Department of Medicine, McDonnell Genome Institute, Siteman Cancer Center, Washington University School of Medicine, St. Louis, Missouri., Li S; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri., von Morze C; Mallinckrodt Institute of Radiology, St. Louis, Missouri., Wulf GM; Department of Medicine and Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, Massachusetts., Shoghi KI; Mallinckrodt Institute of Radiology, St. Louis, Missouri., Ma CX; Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri.

Publikováno v: Cancer research communications [Cancer Res Commun] 2024 Jun 05; Vol. 4 (6), pp. 1430-1440.