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Akademický článek

Let-7 family regulates HaCaT cell proliferation and apoptosis via the ΔNp63/PI3K/AKT pathway

Autor: Li Min, Ding Yi, Tuersong Tayier, Chen Long, Zhang Mei-Lin, Li Tian, Feng Shu-Mei, Guo Qiong

Publikováno v: Open Medicine, Vol 19, Iss 1, Pp e10412-6 (2024)

We evaluated the expression profiles of differentially expressed miRNAs (DEmiRNAs) involved in human fetal skin development via high-throughput sequencing to explore the expression difference and the regulatory role of miRNA in different stages of fe

Externí odkaz: https://doaj.org/article/8568b391cf6e4f5baca1176814bdaef1

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Akademický článek

Proteomic analysis of fetal skin by iTRAQ reveals molecular signals underlying Inner Mongolia Cashmere goat hair follicle initiation

Autor: Lele Wang, Rugang Tian, Gaofeng Wang, Meng Zhao, Yanjun Zhang, Jinquan Li

Publikováno v: All Life, Vol 16, Iss 1 (2023)

Cashmere goats produce wool from primary hair follicles (PHF)and cashmere from secondary hair follicles(SHF). Numerous genetic factors have been identified to affect HF formation, but the mechanism that controls the distinct morphogenesis of PHFs and

Externí odkaz: https://doaj.org/article/44785563d11e4445b11d70a805c51573

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Akademický článek

Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo

Autor: Katarzyna Michalak-Micka, Dominic Rütsche, Luca Mazzone, Vanessa L. Büchler, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)

Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed cytokeratin

Externí odkaz: https://doaj.org/article/60bf9fb1a7994e4a9e025c38298941bb

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Akademický článek

Prenatal diagnosis in dermatology

Autor: Manjyot Gautam, Faaria Ali

Publikováno v: Indian Journal of Paediatric Dermatology, Vol 22, Iss 4, Pp 293-300 (2021)

Prenatal diagnosis (PND) of inherited skin disorders comprises all the diagnostic modalities carried out in utero for couples who are at high risk of producing a child with congenital abnormalities. With the constant research being carried out in the

Externí odkaz: https://doaj.org/article/2403ba5910204497bc10fb1b33fe7d4c

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Akademický článek

Single-cell transcriptome analysis reveals the dynamics of human immune cells during early fetal skin development

Autor: Yingping Xu, Jun Zhang, Yongfei Hu, Xuefei Li, Lihua Sun, Yu Peng, Yuzhe Sun, Bing Liu, Zhilei Bian, Zhili Rong

Publikováno v: Cell Reports, Vol 36, Iss 6, Pp 109524- (2021)

Summary: The immune system of skin develops in stages in mice. However, the developmental dynamics of immune cells in human skin remains elusive. Here, we perform transcriptome profiling of CD45+ hematopoietic cells in human fetal skin at an estimate

Externí odkaz: https://doaj.org/article/552e0a09cfa24870bd7dfbf15b65d5a2

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Akademický článek

Scarless wound healing – a literature review

Autor: Ancuta Muntean, Ionica Stoica, Dan Mircea Enescu

Publikováno v: Romanian Journal of Pediatrics, Vol 68, Iss 3, Pp 160-165 (2019)

The healing of skin lesions, such as traumas or burns, can often result in severe scarring causing important disabilities. The study of fetal skin particularities brings into light its ability of healing wounds in a scarless manner, through regenerat

Externí odkaz: https://doaj.org/article/1f17bceda02347ba84545ec914f18c04

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Akademický článek

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Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids

Autor: Veronika Ramovs, Hans Janssen, Ignacia Fuentes, Amandine Pitaval, Walid Rachidi, Susana M. Chuva de Sousa Lopes, Christian Freund, Xavier Gidrol, Christine L. Mummery, Karine Raymond

Publikováno v: Stem Cell Reports, 17(6), 1279-1288. CELL PRESS
STEM CELL REPORTS

Human induced pluripotent stem cell (hiPSC)-derived hair-bearing skin organoids offer exciting new possibilities for modeling diseases like epidermolysis bullosa (EB). These inherited diseases affect 1 in 30,000 people worldwide and result from pertu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fd9cefc6b5b0a9e8c1e1c34335939e
https://hdl.handle.net/1887/3563158

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Use of ovine acellular peritoneal matrix combined with honey and ovine fetal skin extract in the healing of full-thickness infected burn wounds in a rat model

Autor: Nikahval, Behrooz, Oryan, Ahmad, Memarian, Parastoo, Kamali, Amir

Publikováno v: Veterinary Research Forum

Treatment of infected burn wounds remains a challenge in burn units. Silver-sulfadiazine (SSD) is the most commonly used topical antimicrobial agent in managing these wounds. We aimed to accelerate the healing of burn wounds by combined application o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0f71592688d7cab8c191f954fb534475
http://europepmc.org/articles/PMC7904127

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Akademický článek

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