Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Fetal ovary"'
Publikováno v:
Reproduction and Fertility, Vol 2, Iss 2, Pp 161-171 (2021)
Maternal malnutrition has important developmental consequences for the foetus. Indeed, adverse fetal ovarian development could have lifelong impact, with potentially reduced ovarian reserve and fertility of the offspring. This study investigated the
Externí odkaz:
https://doaj.org/article/5e07f6bb0527464683fd1a273583061a
Autor:
Malene Lundgaard Riis, Anne Jørgensen
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Sex-specific gonadal differentiation is initiated by the expression of SRY in male foetuses. This promotes a signalling pathway directing testicular development, while in female foetuses the absence of SRY and expression of pro-ovarian factors promot
Externí odkaz:
https://doaj.org/article/b197ff4bce1041339c4627c785ec762a
Autor:
Rafiatu Azumah, Katja Hummitzsch, Monica D. Hartanti, Justin C. St. John, Richard A. Anderson, Raymond J. Rodgers
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Polycystic Ovary Syndrome (PCOS) is a multifactorial syndrome with reproductive, endocrine, and metabolic symptoms, affecting about 10% women of reproductive age. Pathogenesis of the syndrome is poorly understood with genetic and fetal origins being
Externí odkaz:
https://doaj.org/article/bf592aeb2aa342d192d0668fa782a4e8
Autor:
Flaviana Cau, Daniela Fanni, Clara Gerosa, Maria Carolina Botta, Flaminia Bardanzellu, Sara Aversa, Ester Sorrentino, Francesco Ronchi, Cristiana Bellan, Gavino Faa, Massimo Castagnola
Publikováno v:
Journal of Pediatric and Neonatal Individualized Medicine, Vol 10, Iss 1, Pp e100118-e100118 (2021)
Oct-4 (Octamer-binding transcription factor 4) is a member of the POU (Pit-Oct-Unc) family. During development, Oct-4 is expressed in embryonic stem cells and in germ cell precursors. In this study, we investigated the expression of Oct-4 in the ovar
Externí odkaz:
https://doaj.org/article/b3844cd92edf449daee4fd85f5aaa432
Autor:
Benoit Loup, Elodie Poumerol, Luc Jouneau, Paul A. Fowler, Corinne Cotinot, Béatrice Mandon-Pépin
Publikováno v:
Reproductive Toxicology
Reproductive Toxicology, 2022, 111, p. 166-177. ⟨10.1016/j.reprotox.2022.06.001⟩
Reproductive Toxicology, 2022, 111, p. 166-177. ⟨10.1016/j.reprotox.2022.06.001⟩
International audience; The negative in utero effects of bisphenol A (BPA) on female reproduction are of concern since the ovarian reserve of primordial follicles is constituted during the fetal period. This time-window is difficult to access, partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d899ba0e75e43fdeaa30a87d9ececa1
https://doi.org/10.1016/j.reprotox.2022.06.001
https://doi.org/10.1016/j.reprotox.2022.06.001
Autor:
Maya R. Overland, Yi Li, Amber Derpinghaus, Sena Aksel, Mei Cao, Nicholas Ladwig, Gerald R. Cunha, Marta Himelreich-Perić, Laurence S. Baskin
A definition of normal human fetal and early postnatal ovarian development is critical to the ability to accurately diagnose the presence or absence of functional ovarian tissue in clinical specimens. Through assembling an extensive histologic and im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063efe6bc090812e792ff54c796ffbb5
https://doi.org/10.1016/j.diff.2022.10.005
https://doi.org/10.1016/j.diff.2022.10.005
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Vincent Lavoué, Millissia Ben Maamar, Frédéric Chalmel, Sabrina Leverrier-Penna, Séverine Mazaud-Guittot, Antoine Rolland, Estelle Lecluze, Bertrand Evrard, Paul Fowler, Bernard Jégou, Panagiotis Filis, Isabelle Coiffec
Publikováno v:
Human Reproduction
Human Reproduction, 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩
Human Reproduction, Oxford University Press (OUP), 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩
Human Reproduction, 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩
Human Reproduction, Oxford University Press (OUP), 2020, 35 (5), pp.1099-1119. ⟨10.1093/humrep/deaa041⟩
STUDY QUESTION Which transcriptional program triggers sex differentiation in bipotential gonads and downstream cellular events governing fetal testis and ovary development in humans? SUMMARY ANSWER The characterization of a dynamically regulated prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eff80fcd5565d46c242ace9869424ae
https://doi.org/10.1093/humrep/deaa041
https://doi.org/10.1093/humrep/deaa041
Autor:
Laetitia L Lecante, Sabrina Leverrier-Penna, Thomas Gicquel, Frank Giton, Nathalie Costet, Christèle Desdoits-Lethimonier, Laurianne Lesné, Bernard Fromenty, Vincent Lavoué, Antoine D Rolland, Séverine Mazaud-Guittot
Publikováno v:
Journal of Clinical Endocrinology and Metabolism
Journal of Clinical Endocrinology and Metabolism, 2022, 107 (6), pp.1647-1661. ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2022, ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, 2022, 107 (6), pp.1647-1661. ⟨10.1210/clinem/dgac080⟩
Journal of Clinical Endocrinology and Metabolism, Endocrine Society, 2022, ⟨10.1210/clinem/dgac080⟩
Context Acetaminophen (APAP, paracetamol) is widely used by pregnant women. Although long considered safe, growing evidence indicates that APAP is an endocrine disruptor since in utero exposure may be associated with a higher risk of male genital tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c620e0bd4b6d4d74b06d25f54d6da0ab
https://hal.science/hal-03578173
https://hal.science/hal-03578173
Autor:
Yi Zhou, Yanni Feng, Lan Li, Shu-Hua Zou, Ze-Li Han, Xiao-Feng Sun, Wei Ge, Yong Zhao, Fan Yang, Massimo De Felici, Xun-Si Qin, Wei Shen, Shun-Feng Cheng
Publikováno v:
Aging (Albany NY)
In the present paper, we found that human fetal ovaries (at ~16 weeks) express the transcripts for several subunits of the nicotinic acetylcholine receptor (nAChR). Exposure to the drug in vitro resulted in the marked increase of apoptosis in the ova
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf603a9acc4e490b4314951f4db46ea
http://europepmc.org/articles/PMC6075447
http://europepmc.org/articles/PMC6075447