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pro vyhledávání: '"Fetal haematopoiesis"'
Akademický článek
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Autor:
Yang Liu, Qi Chen, Hyun-Woo Jeong, Bong Ihn Koh, Emma C. Watson, Cong Xu, Martin Stehling, Bin Zhou, Ralf H. Adams
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The colonization of bone marrow by haematopoietic stem and progenitor cells is critical for lifelong blood cell formation. Here the authors report distinct features of fetal bone marrow and show that artery-derived signals promote haematopoietic colo
Externí odkaz:
https://doaj.org/article/cbd059c3da144a1faae8a9b2837738b6
Autor:
Hasaart, Karlijn A. L.1, Manders, Freek1, van der Hoorn, Marie-Louise2, Verheul, Mark1, Poplonski, Tomasz3, Kuijk, Ewart4, de Sousa Lopes, Susana M. Chuva5, van Boxtel, Ruben1 R.vanBoxtel@prinsesmaximacentrum.nl
Publikováno v:
Scientific Reports. 7/31/2020, Vol. 10 Issue 1, p1-14. 14p.
Autor:
Ralf H. Adams, Yang Liu, Xu C, Qi Chen, Watson Ec, Martin Stehling, Bingjie Zhou, Hyun-Woo Jeong
Local signals provided by cells in specialized niche microenvironments regulate stem cell behaviour in many different organs and species. In adult mammalian bone marrow (BM), leptin receptor-positive (LepR+) reticular cells express secreted factors t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d248526eecf132dacb17311ebda5d5ff
https://doi.org/10.1101/2021.03.05.434039
https://doi.org/10.1101/2021.03.05.434039
Autor:
Susana M. Chuva de Sousa Lopes, Marie-Louise P. van der Hoorn, Ruben van Boxtel, Ewart W. Kuijk, Mark Verheul, Karlijn Hasaart, Freek Manders, Tomasz Poplonski
Publikováno v:
Scientific Reports
Scientific Reports, 10. Nature Research
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, 10. Nature Research
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Children show a higher incidence of leukemia compared to young adolescents, yet their cells have less age-related (oncogenic) somatic mutations. Newborns with Down syndrome have an even higher risk of developing leukemia, which is thought to be drive
Autor:
Georg Haecker, Fabian Schuler, Sehar Afreen, Andreas Villunger, Miriam Erlacher, Claudia Manzl
Checkpoint kinase 1 is critical for S-phase fidelity and preventing premature mitotic entry in the presence of DNA damage. Tumour cells have developed a strong dependence on CHK1 for survival and hence this kinase has developed into a popular drug-ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e59e929edf1f2bf06a23cd7f33ab364
https://doi.org/10.1101/413310
https://doi.org/10.1101/413310
Autor:
O'Connor, David
Children with Down syndrome (DS; trisomy 21, T21) have a 500-fold risk of developing acute megakaryoblastic leukaemia (AMKL) in early childhood compared to children without DS. DS-AMKL is preceded by a transient neonatal leukaemia, unique to DS, caus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40baba819ec4fe147b80e33c315a7de
http://hdl.handle.net/10044/1/29169
http://hdl.handle.net/10044/1/29169
Autor:
Marderstein, Andrew R., De Zuani, Marco, Moeller, Rebecca, Bezney, Jon, Padhi, Evin M., Wong, Shuo, Coorens, Tim H. H., Xie, Yilin, Xue, Haoliang, Montgomery, Stephen B., Cvejic, Ana
Publikováno v:
Nature; Oct2024, Vol. 634 Issue 8032, p104-112, 9p
Autor:
Alex J. Eggink, Sten P. Willemsen, Robert de Jonge, Eric A.P. Steegers, Marten van der Zee, Régine P.M. Steegers-Theunissen, Jacqueline Lagendijk, Emilie M. Herzog
Publikováno v:
Herzog, E M, Eggink, A J, van der Zee, M, Lagendijk, J, Willemsen, S P, de Jonge, R, Steegers, E A P & Steegers-Theunissen, R P M 2016, ' The impact of early-and late-onset preeclampsia on umbilical cord blood cell populations ', Journal of Reproductive Immunology, vol. 116, pp. 81-85 . https://doi.org/10.1016/j.jri.2016.05.002
Journal of Reproductive Immunology, 116, 81-85. Elsevier Ireland Ltd
Journal of Reproductive Immunology, 116, 81-85. Elsevier Ireland Ltd
Pregnancies complicated by preeclampsia (PE) are characterised by an enhanced maternal and fetal inflammatory response with increased numbers of leukocytes in maternal peripheral blood. The impact of PE on newborn umbilical cord blood cell (UCBC) pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4add969c912fce2e23f7a87c4ae6c7f
https://research.vumc.nl/en/publications/54ef0e6d-564d-47a9-b4a6-d806a27b5540
https://research.vumc.nl/en/publications/54ef0e6d-564d-47a9-b4a6-d806a27b5540
Autor:
Jones, D. R. E.1 d.r.e.jones@nottingham.ac.uk
Publikováno v:
Fetal Diagnosis & Therapy. May/Jun2004, Vol. 19 Issue 3, p207-211. 5p.