Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Fessing, Michael"'
Autor:
Chen, G-D., Fatima, I., Xu, Q, Rozhkova, E., Fessing, Michael Y., Mardaryev, Andrei N., Sharov, A.A., Xu, G-L., Botchkarev, Vladimir A.
Yes
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre
Externí odkaz:
http://hdl.handle.net/10454/19330
Spatial genome organization in the cell nucleus plays a crucial role in the control of genome functions. Our knowledge about spatial genome organization is relying on the advances in gene imaging technologies and the biochemical approaches based on t
Externí odkaz:
http://hdl.handle.net/10454/18511
Autor:
Rapisarda, Valentina, Malashchuk, Igor, Asamaowei, Inemo E., Poterlowicz, Krzysztof, Fessing, Michael Y., Sharov, A.A., Karakesisoglou, I., Botchkarev, Vladimir A., Mardaryev, Andrei N.
Yes
The maintenance of a proper nuclear architecture and 3D organization of the genes, enhancer elements and transcription machinery plays an essential role in tissue development and regeneration. Here we show that in the developing skin, epider
The maintenance of a proper nuclear architecture and 3D organization of the genes, enhancer elements and transcription machinery plays an essential role in tissue development and regeneration. Here we show that in the developing skin, epider
Externí odkaz:
http://hdl.handle.net/10454/12280
Autor:
Poterlowicz, Krzysztof, Yarker, Joanne L., Malashchuk, Igor, Lajoie, B.R., Mardaryev, Andrei N., Gdula, M.R., Sharov, A.A., Kohwi-Shigematsu, T., Botchkarev, Vladimir A., Fessing, Michael Y.
Yes
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologi
Mammalian genomes contain several dozens of large (>0.5 Mbp) lineage-specific gene loci harbouring functionally related genes. However, spatial chromatin folding, organization of the enhancer-promoter networks and their relevance to Topologi
Externí odkaz:
http://hdl.handle.net/10454/17918
Autor:
Mardaryev, Andrei N., Liu, B., Rapisarda, Valentina, Poterlowicz, Krzysztof, Malashchuk, Igor, Rudolf, Jana, Sharov, A.A., Jahoda, C.J., Fessing, Michael Y., Benitah, S., Xu, G., Botchkarev, Vladimir A.
Yes
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a criti
During development, multipotent progenitor cells establish lineage-specific programmers of gene activation and silencing underlying their differentiation into specialized cell types. We show that the Polycomb component Cbx4 serves as a criti
Externí odkaz:
http://hdl.handle.net/10454/10161
In mammals, hairs fulfil a number of important functions including thermoregulation, collecting sensory information, protection against environmental stressors, social communication and mimicry [1]. Hairs are produced by the pilosebaceous unit that c
Externí odkaz:
http://hdl.handle.net/10454/10429
Autor:
Lewis, Christopher J., Mardaryev, Andrei N., Sharov, A.A., Fessing, Michael Y., Botchkarev, Vladimir A.
Significance: Epigenetic regulatory mechanisms are essential for epidermal homeostasis and contribute to the pathogenesis of many skin diseases, including skin cancer and psoriasis. However, while the epigenetic regulation of epidermal homeostasis is
Externí odkaz:
http://hdl.handle.net/10454/6830
Autor:
Fessing, Michael Y.
Chromatin structure and spatial interactions between proximal and distal gene regulatory elements, including gene core promoters and enhancers, are important in the control of gene transcription. In this issue, Oh et al. characterized an AP-1-depende
Externí odkaz:
http://hdl.handle.net/10454/6831
Autor:
Gdula, Michal R., Poterlowicz, Krzysztof, Mardaryev, Andrei N., Sharov, A.A., Fessing, Michael Y., Botchkarev, Vladimir A., Peng, Yonghong
The nucleus of epidermal keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly changed during terminal differentiation and transition of the genome from a transcriptionally active state seen in the basal
Externí odkaz:
http://hdl.handle.net/10454/7221