RNA-based engineering of inducible CRISPR-Cas9 transcription factors for de novo assembly of eukaryotic gene circuits

Autor: Ferry, Quentin R. V.

Synthetic biology in mammalian cells holds great promise for reverse engineering biological processes and rewiring cellular behaviors for therapeutic purpose. An essential aspect in our ability to reprogram the cellular code is the availability of hi

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In situ functional dissection of RNA cis-regulatory elements by multiplex CRISPR-Cas9 genome engineering.

Autor: Qianxin Wu, Ferry, Quentin R. V., Baeumler, Toni A., Michaels, Yale S., Vitsios, Dimitrios M., Habib, Omer, Arnold, Roland, Xiaowei Jiang, Maio, Stefano, Steinkraus, Bruno R., Tapia, Marta, Piazza, Paolo, Ni Xu, Holländer, Georg A., Milne, Thomas A., Jin-Soo Kim, Enright, Anton J., Bassett, Andrew R., Fulga, Tudor A.

Publikováno v: Nature Communications; 12/13/2017, Vol. 8 Issue 1, p1-17, 17p

Controlling the Activity of CRISPR Transcriptional Regulators with Inducible sgRNAs.

Autor: Ferry QRV; Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK. quentinf.postdoc@gmail.com., Fulga TA; Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.

Publikováno v: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2162, pp. 153-184.