Zobrazeno 1 - 10
of 258
pro vyhledávání: '"Ferroquine"'
Autor:
Adama Gansane, Moussa Lingani, Adoke Yeka, Alain Nahum, Marielle Bouyou-Akotet, Ghyslain Mombo-Ngoma, Grace Kaguthi, Catalina Barceló, Bart Laurijssens, Cathy Cantalloube, Fiona Macintyre, Elhadj Djeriou, Andreas Jessel, Raphaël Bejuit, Helen Demarest, Anne Claire Marrast, Siaka Debe, Halidou Tinto, Afizi Kibuuka, Diolinda Nahum, Denise Patricia Mawili-Mboumba, Rella Zoleko-Manego, Irene Mugenya, Frederick Olewe, Stephan Duparc, Bernhards Ogutu
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background The contribution of artefenomel to the clinical and parasiticidal activity of ferroquine and artefenomel in combination in uncomplicated Plasmodium falciparum malaria was investigated. Methods This Phase 2a, randomized, open-label
Externí odkaz:
https://doaj.org/article/f65785a4b7b84297a418e877222c7d6a
Autor:
Yeka Adoke, Rella Zoleko-Manego, Serge Ouoba, Alfred B. Tiono, Grace Kaguthi, Juvêncio Eduardo Bonzela, Tran Thanh Duong, Alain Nahum, Marielle Bouyou-Akotet, Bernhards Ogutu, Alphonse Ouedraogo, Fiona Macintyre, Andreas Jessel, Bart Laurijssens, Mohammed H. Cherkaoui-Rbati, Cathy Cantalloube, Anne Claire Marrast, Raphaël Bejuit, David White, Timothy N. C. Wells, Florian Wartha, Didier Leroy, Afizi Kibuuka, Ghyslain Mombo-Ngoma, Daouda Ouattara, Irène Mugenya, Bui Quang Phuc, Francis Bohissou, Denise P. Mawili-Mboumba, Fredrick Olewe, Issiaka Soulama, Halidou Tinto, the FALCI Study Group
Publikováno v:
Malaria Journal, Vol 20, Iss 1, Pp 1-25 (2021)
Abstract Background For uncomplicated Plasmodium falciparum malaria, highly efficacious single-dose treatments are expected to increase compliance and improve treatment outcomes, and thereby may slow the development of resistance. The efficacy and sa
Externí odkaz:
https://doaj.org/article/9984adbb71374f0b9bb2d7ec8eac47cd
Akademický článek
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Akademický článek
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Akademický článek
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Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-7 (2014)
Abstract Background Schistosomiasis is a neglected tropical disease and drug-repurposing is a useful strategy to fill its exhausted drug development pipeline. The ferrocenyl analogue of chloroquine, ferroquine, is an antimalarial in late-stage drug d
Externí odkaz:
https://doaj.org/article/11aa53ecf1b2499a91624af77fef08bc
Autor:
Vipan Kumar, Bharvi Sharma
Publikováno v:
Journal of Medicinal Chemistry. 64:16865-16921
Ferrocene is an important structural core in bioorganometallic chemistry because of its inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are two of the most notable contributions of ferrocene to medicinal ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54ca93e53af43b1f5cf40a91eb5ad07
https://doi.org/10.1021/acs.jmedchem.1c00390
https://doi.org/10.1021/acs.jmedchem.1c00390
Publikováno v:
Molecules, Vol 24, Iss 19, p 3604 (2019)
Malaria and cancer are chronic diseases. The challenge with drugs available for the treatment of these diseases is drug toxicity and resistance. Ferrocene is a potent organometallic which have been hybridized with other compounds resulting in compoun
Externí odkaz:
https://doaj.org/article/7a5420313db44be694dad8cdc17ed6a3
Publikováno v:
Facta universitatis - series: Physics, Chemistry and Technology. 18:1-37
Great progress in the fight against malaria has been made in the last decade. Nevertheless, the development of resistance to almost all commonly used antimalarial drugs poses a major threat to the sustainability of this progress and highlights the ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaad79ee1fb62b98f0fcacc521d4827e
https://doi.org/10.2298/fupct2001001a
https://doi.org/10.2298/fupct2001001a
Publikováno v:
Parasite, Vol 18, Iss 3, Pp 207-214 (2011)
Ferroquine (FQ, SSR97193) is currently the most advanced organometallic drug candidate and about to complete phase II clinical trials as a treatment for uncomplicated malaria. This ferrocenecontaining compound is active against both chloroquine-susce
Externí odkaz:
https://doaj.org/article/3b5a01cf1b414674a2ced4ec448008cf