Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling

Autor: Yang, Steven Hoseong, Andl, Thomas, Grachtchouk, Vladimir, Wang, Aiqin, Liu, Jianhong, Syu, Li-Jyun, Ferris, Jenny, Wang, Timothy S, Glick, Adam B, Millar, Sarah E, Dlugosz, Andrzej A

Constitutive Hedgehog (Hh) signaling underlies several human tumors1, including basal cell carcinoma (BCC) and basaloid follicular hamartoma in skin2,3. Intriguingly, superficial BCCs arise as de novo epithelial buds resembling embryonic hair germs4�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4f65dda2120c0853c7cf2f5bd2da11a
https://europepmc.org/articles/PMC2688690/

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/β-catenin signaling.

Autor: Steven Hoseong Yang, Andl, Thomas, Grachtchouk, Vladimir, Aiqin Wang, Jianhong Liu, Li-Jyun Syu, Ferris, Jenny, Wang, Timothy S., Glick, Adam B., Millar, Sarah E., Dlugosz, Andrzej A.

Publikováno v: Nature Genetics; Sep2008, Vol. 40 Issue 9, p1130-1135, 6p, 4 Color Photographs

Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta3-catenin signaling.

Autor: Yang SH; Department of Dermatology and Comprehensive Cancer Center, University of Michigan Medical School, 1500 East Medical Center Drive, Ann Arbor, Michigan 48109, USA., Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA

Publikováno v: Nature genetics [Nat Genet] 2008 Sep; Vol. 40 (9), pp. 1130-5.