Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ferri, Soheilian"'
Autor:
Jonathan M. O. Rawson, Olga A. Nikolaitchik, Jennifer A. Yoo, Xayathed Somoulay, Matthew A. Brown, Franck S. Mbuntcha Bogni, Vinay K. Pathak, Ferri Soheilian, Ryan L. Slack, Stefan G. Sarafianos, Wei-Shau Hu
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Frequent recombination is a hallmark of retrovirus replication. In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health. These recom
Externí odkaz:
https://doaj.org/article/86bec7df75394f38ab143fb2a046a35d
Autor:
Shu Yang, Kirill Gorshkov, Emily M. Lee, Miao Xu, Yu-Shan Cheng, Nuo Sun, Ferri Soheilian, Natalia de Val, Guoli Ming, Hongjun Song, Hengli Tang, Wei Zheng
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The 2015 to 2016 outbreak of Zika virus (ZIKV) infections in the Americas coincided with a dramatic increase in neurodevelopmental abnormalities, including fetal microcephaly, in newborns born to infected women. In this study, we observed mitochondri
Externí odkaz:
https://doaj.org/article/9b62b642d6664fefa85116988315a422
Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity
Autor:
Kazuaki Monde, Hiromi Terasawa, Yusuke Nakano, Ferri Soheilian, Kunio Nagashima, Yosuke Maeda, Akira Ono
Publikováno v:
Retrovirology, Vol 14, Iss 1, Pp 1-16 (2017)
Abstract Background Human endogenous retroviruses (HERVs), the remnants of ancient retroviral infections, constitute approximately 8% of human genomic DNA. Since HERV-K Gag expression is induced by HIV-1 Tat in T cells, induced HERV-K proteins could
Externí odkaz:
https://doaj.org/article/c46931b9853345b8a53d6d300415ab46
Autor:
Mariia Novikova, Lucas J. Adams, Juan Fontana, Anna T. Gres, Muthukumar Balasubramaniam, Dennis C. Winkler, Sagar B. Kudchodkar, Ferri Soheilian, Stefan G. Sarafianos, Alasdair C. Steven, Eric O. Freed
Publikováno v:
mBio, Vol 9, Iss 5 (2018)
ABSTRACT Late in the HIV-1 replication cycle, the viral structural protein Gag is targeted to virus assembly sites at the plasma membrane of infected cells. The capsid (CA) domain of Gag plays a critical role in the formation of the hexameric Gag lat
Externí odkaz:
https://doaj.org/article/d1bc164630d541f6abb520b9b82a3d58
Autor:
Olga A Nikolaitchik, Kari A Dilley, William Fu, Robert J Gorelick, S-H Sheldon Tai, Ferri Soheilian, Roger G Ptak, Kunio Nagashima, Vinay K Pathak, Wei-Shau Hu
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003249 (2013)
How retroviruses regulate the amount of RNA genome packaged into each virion has remained a long-standing question. Our previous study showed that most HIV-1 particles contain two copies of viral RNA, indicating that the number of genomes packaged is
Externí odkaz:
https://doaj.org/article/6c5193d48ad84355b3127114444ac64a
Autor:
Ferri Soheilian, Velayoudame Parthibane, Lino Tessarollo, Kunio Nagashima, Stephen D. Fox, Jonathan R. Keller, Usha Acharya, Diwash Acharya, Jairaj K. Acharya, Thiruvaimozhi Abimannan, Thorkell Andresson, Jing Lin, Sargur Madabushi Srideshikan, Acong Yang, Kimberly D. Klarmann
Publikováno v:
The Journal of Biological Chemistry
Serine palmitoyltransferase complex (SPT) mediates the first and rate-limiting step in the de novo sphingolipid biosynthetic pathway. The larger subunits SPTLC1 and SPTLC2/SPTLC3 together form the catalytic core while a smaller third subunit either S
Autor:
Kayoko Waki, Stewart R Durell, Ferri Soheilian, Kunio Nagashima, Scott L Butler, Eric O Freed
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1002997 (2012)
Processing of the Gag precursor protein by the viral protease during particle release triggers virion maturation, an essential step in the virus replication cycle. The first-in-class HIV-1 maturation inhibitor dimethylsuccinyl betulinic acid [PA-457
Externí odkaz:
https://doaj.org/article/b84484a77b664f9fa431d9c74fa137c7
Autor:
Ashley Ubaldini, Xiantao Wang, Ferri Soheilian, Yoshimi Endo Greer, Dan Crooks, Stanley Lipkowitz, Christina H. Stuelten, Luca Gattinoni, Donna Voeller, Roberto Weigert, Markus Hafner, Natalie Porat-Shliom, Vinodh N. Rajapakse, Parthav Jailwala, Bao Tran, Yun Ji, Jyoti Shetty, Yves Pommier, Maggie Cam, Celia Islam, W. Marston Linehan, Samuel F. Gilbert, Vishal N. Koparde, William C. Reinhold, Kunio Nagashima, Martin Lang
Publikováno v:
Oncotarget. 9:18454-18479
// Yoshimi Endo Greer 1 , Natalie Porat-Shliom 2 , Kunio Nagashima 3 , Christina Stuelten 2 , Dan Crooks 4 , Vishal N. Koparde 5 , Samuel F. Gilbert 1 , Celia Islam 1 , Ashley Ubaldini 1 , Yun Ji 6 , Luca Gattinoni 6 , Ferri Soheilian 3 , Xiantao Wan
Autor:
Karine Gousset, Sherimay D Ablan, Lori V Coren, Akira Ono, Ferri Soheilian, Kunio Nagashima, David E Ott, Eric O Freed
Publikováno v:
PLoS Pathogens, Vol 4, Iss 3, p e1000015 (2008)
HIV-1 particle production is driven by the Gag precursor protein Pr55(Gag). Despite significant progress in defining both the viral and cellular determinants of HIV-1 assembly and release, the trafficking pathway used by Gag to reach its site of asse
Externí odkaz:
https://doaj.org/article/510bb4203f7841c1ac00215eae83cfd5
Autor:
Miao Xu, Juan J. Marugan, Rong Li, Yan Long, Silvia Muro, Zhiyuan Li, Jeanette Beers, Sheng Dai, Mengqiao Wang, Wei Zheng, Ulrich Baxa, Guokai Chen, Ferri Soheilian, Roscoe O. Brady
Publikováno v:
Stem Cells Translational Medicine
Niemann-Pick disease type A (NPA)-induced pluripotent stem cells from patient dermal fibroblasts were differentiated into neural stem cells. By using the differentiated NPA neuronal cells as a cell-based disease model system, α-tocopherol, δ-tocoph