Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd

Autor: Zichen Wang, Caroline D. Monteiro, Kathleen M. Jagodnik, Nicolas F. Fernandez, Gregory W. Gundersen, Andrew D. Rouillard, Sherry L. Jenkins, Axel S. Feldmann, Kevin S. Hu, Michael G. McDermott, Qiaonan Duan, Neil R. Clark, Matthew R. Jones, Yan Kou, Troy Goff, Holly Woodland, Fabio M R. Amaral, Gregory L. Szeto, Oliver Fuchs, Sophia M. Schüssler-Fiorenza Rose, Shvetank Sharma, Uwe Schwartz, Xabier Bengoetxea Bausela, Maciej Szymkiewicz, Vasileios Maroulis, Anton Salykin, Carolina M. Barra, Candice D. Kruth, Nicholas J. Bongio, Vaibhav Mathur, Radmila D Todoric, Udi E. Rubin, Apostolos Malatras, Carl T. Fulp, John A. Galindo, Ruta Motiejunaite, Christoph Jüschke, Philip C. Dishuck, Katharina Lahl, Mohieddin Jafari, Sara Aibar, Apostolos Zaravinos, Linda H. Steenhuizen, Lindsey R. Allison, Pablo Gamallo, Fernando de Andres Segura, Tyler Dae Devlin, Vicente Pérez-García, Avi Ma’ayan

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

A wealth of gene expression data is publicly available, yet is little use without additional human curation. Ma’ayan and colleagues report a crowdsourcing project involving over 70 participants to annotate and analyse thousands of human disease-rel

Externí odkaz: https://doaj.org/article/a8f2b28d890e4a0e99fc75b9634da8c0

Afro-Latin American Pharmacogenetics of CYP2D6, CYP2C9, and CYP2C19 in Dominicans: A Study from the RIBEF-CEIBA Consortium

Autor: Mariela Guevara, Fernanda Rodrigues-Soares, Carla González de la Cruz, Fernando de Andrés, Ernesto Rodríguez, Eva Peñas-Lledó, Adrián LLerena, CEIBA Consortium of the Ibero-American Network of Pharmacogenetics and Pharmacogenomics RIBEF

Publikováno v: Pharmaceutics, Vol 16, Iss 11, p 1399 (2024)

Background/Objectives: Research on pharmacogenetic variability in response to prescribed drugs and across ethnic groups is essential for personalized medicine, particularly in admixed and unstudied populations. For the first time, this study examines

Externí odkaz: https://doaj.org/article/aa8f3da5e6c549d58df50f18597e8685

THU0187 EFFICIENCY OF TREATMENT SEQUENCES CONTAINING TOFACITINIB FOR RHEUMATOID ARTHRITIS IN SPAIN

Autor: Susana Gómez, Miguel A. Casado, María Montoro, Fernando De Andres, F. Navarro, Itziar Oyagüez, José L. Pablos, Jose Manuel Martinez Sesmero, C. Peral, Alejandro Balsa, M. Valderrama

Publikováno v: Poster Presentations.

Background: The availability of oral janus kinase inhibitors, as tofacitinib, has extended the treatment pathways for management of patients with rheumatoid arthritis (RA) Objectives: To assess the cost-effectiveness of tofacitinib as second-line tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::489d2020b120e406d10d201a4f2a3a19
https://doi.org/10.1136/annrheumdis-2019-eular.6741

Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd

Autor: Sophia Miryam Schüssler-Fiorenza Rose, Anton Salykin, Xabier Bengoetxea Bausela, Linda H. Steenhuizen, Qiaonan Duan, Oliver Fuchs, Christoph Jüschke, Neil R. Clark, Caroline D. Monteiro, Pablo Gamallo, Apostolos Zaravinos, Vicente Perez-Garcia, Carl T. Fulp, Kathleen M. Jagodnik, Nicolas F. Fernandez, Tyler Dae Devlin, Philip C. Dishuck, Apostolos Malatras, Candice D. Kruth, Avi Ma'ayan, Gregory W. Gundersen, Sherry L. Jenkins, Katharina Lahl, Maciej Szymkiewicz, Holly Woodland, Vaibhav Mathur, Yan Kou, Michael G. McDermott, Sara Aibar, Uwe Schwartz, Mohieddin Jafari, Nicholas J. Bongio, Carolina M. Barra, Shvetank Sharma, Vasileios Maroulis, John A. Galindo, Udi Rubin, Fabio M R. Amaral, Ruta Motiejunaite, Kevin Hu, Zichen Wang, Fernando de Andres Segura, Matthew R. Jones, Axel S. Feldmann, Troy Goff, Radmila D. Todoric, Andrew D. Rouillard, Lindsey R. Allison, Gregory L. Szeto

Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Nature Communications
RUIdeRA. Repositorio Institucional de la UCLM
instname
Wang, Z, Monteiro, C D, Jagodnik, K M, Fernandez, N F, Gundersen, G W, Rouillard, A D, Jenkins, S L, Feldmann, A S, Hu, K S, McDermott, M G, Duan, Q, Clark, N R, Jones, M R, Kou, Y, Goff, T, Woodland, H, Amaral, F M R, Szeto, G L, Fuchs, O, Schüssler-Fiorenza Rose, S M, Sharma, S, Schwartz, U, Bausela, X B, Szymkiewicz, M, Maroulis, V, Salykin, A, Barra, C M, Kruth, C D, Bongio, N J, Mathur, V, Todoric, R D, Rubin, U E, Malatras, A, Fulp, C T, Galindo, J A, Motiejunaite, R, Jüschke, C, Dishuck, P C, Lahl, K, Jafari, M, Aibar, S, Zaravinos, A, Steenhuizen, L H, Allison, L R, Gamallo, P, De Andres Segura, F, Dae Devlin, T, Pérez-García, V & Ma'ayan, A 2016, ' Extraction and analysis of signatures from the Gene Expression Omnibus by the crowd ', Nature Communications, vol. 7, 12846 . https://doi.org/10.1038/ncomms12846
Nature

Gene expression data are accumulating exponentially in public repositories. Reanalysis and integration of themed collections from these studies may provide new insights, but requires further human curation. Here we report a crowdsourcing project to a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9c9491a70ded33061255f09b66ada8
https://doaj.org/article/a8f2b28d890e4a0e99fc75b9634da8c0

Primary prevention of cardiovascular diseases with statins in patients with diabetes

Autor: César de la Fuente Honrubia, Ferrán Catalá-López, Fernando de Andres-Trelles, Diego Macías Saint-Gerons

Publikováno v: Medicina Clínica (English Edition). 144:285-287

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d26d61a5f902fa2425c275536c9b8d5a
https://doi.org/10.1016/j.medcle.2014.05.004