Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Fernando Teran Arce"'
Autor:
Ana Martinez Hernandez, Hendrik Urbanke, Alan L Gillman, Joon Lee, Sergey Ryazanov, Hope Y Agbemenyah, Eva Benito, Gaurav Jain, Lalit Kaurani, Gayane Grigorian, Andrei Leonov, Nasrollah Rezaei‐Ghaleh, Petra Wilken, Fernando Teran Arce, Jens Wagner, Martin Fuhrmann, Mario Caruana, Angelique Camilleri, Neville Vassallo, Markus Zweckstetter, Roland Benz, Armin Giese, Anja Schneider, Martin Korte, Ratnesh Lal, Christian Griesinger, Gregor Eichele, Andre Fischer
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2017)
Abstract Alzheimer's disease is a devastating neurodegenerative disease eventually leading to dementia. An effective treatment does not yet exist. Here we show that oral application of the compound anle138b restores hippocampal synaptic and transcrip
Externí odkaz:
https://doaj.org/article/c508142ad7ed44dda436f67105c1fa85
Autor:
N. Malithi Fonseka, Fernando Teran Arce, Hamish S. Christie, Craig A. Aspinwall, S. Scott Saavedra
Publikováno v:
Langmuir. 38:100-111
Polymerization enhances the stability of a planar supported lipid bilayer (PSLB) but it also changes its chemical and mechanical properties, attenuates lipid diffusion, and may affect the activity of integral membrane proteins. Mixed bilayers compose
Autor:
Jillian Madine, Scott Younger, Hyunbum Jang, Joe G.N. Garcia, Martin J. Niemiec, Ruth Nussinov, Hannah A. Davies, Fernando Teran Arce, Raymond Q. Migrino
Publikováno v:
Biophysical Journal
Medin, a 50-amino-acid cleavage product of the milk fat globule-EGF factor 8 protein, is one of the most common forms of localized amyloid found in the vasculature of individuals older than 50 years. Medin induces endothelial dysfunction and vascular
Autor:
Danny Bluestein, S. Scott Saavedra, Lisa M. Wise, John G. Purdy, Fernando Teran Arce, Jawaad Sheriff, Marvin J. Slepian, Yana Roka-Moiia, Alice Sweedo
Publikováno v:
Cell Mol Bioeng
INTRODUCTION: Platelet activation by mechanical means such as shear stress exposure, is a vital driver of thrombotic risk in implantable blood-contacting devices used in the treatment of heart failure. Lipids are essential in platelets activation and
Autor:
Fernando Teran Arce, Young Hun Kim, Hyunbum Jang, Ruth Nussinov, Jerry Yang, Alan L. Gillman, Bruce L. Kagan, Ratnesh Lal, Joon Lee
Publikováno v:
ACS chemical neuroscience, vol 8, iss 6
Amyloid β (Aβ) oligomers are the predominant toxic species in the pathology of Alzheimer’s disease. The prevailing mechanism for toxicity by Aβ oligomers includes ionic homeostasis destabilization in neuronal cells by forming ion channels. These
Autor:
Donald J. Sirbuly, Ratnesh Lal, Ilsun Yoon, Joshua Villanueva, Fernando Teran Arce, Joon Lee, Qian Huang
Publikováno v:
Nanoscale. 8:17102-17107
Precise positioning of a plasmonic nanoparticle (NP) near a small dielectric surface is not only necessary for understanding gap-dependent interactions between a metal and dielectric but it is also a critical component in building ultrasensitive mole
Autor:
Soracha Thamphiwatana, Yuesong Shi, Josh Villanueva, Joon Lee, Xuanyi Ma, Fernando Teran Arce, Ilsun Yoon, Liangfang Zhang, Shaochen Chen, Pavimol Angsantikul, Donald J. Sirbuly, Ratnesh Lal, Qian Huang, Justin Liu
Publikováno v:
Nature photonics. 11
Ultrasensitive nanomechanical instruments, including the atomic force microscope (AFM)1-4 and optical and magnetic tweezers5-8, have helped shed new light on the complex mechanical environments of biological processes. However, it is difficult to sca
Autor:
Roland Benz, Martin Fuhrman, Hope Y Agbemenyah, Joon Lee, Lalit Kaurani, Gregor Eichele, Markus Zweckstetter, Gaurav Jain, Nasrollah Rezaei-Ghaleh, Andre Fischer, Alan L. Gillman, Gayane Grigorian, Ratnesh Lal, Sergey Ryazanov, Mario Caruana, Armin Giese, Christian Griesinger, Martin Korte, Eva Benito, Angelique Camilleri, Andrei Leonov, Neville Vassallo, Jens Wagner, Fernando Teran Arce, Hendrik Urbanke, Ana Martinez Hernandez, Anja Schneider, Petra Wilken
Publikováno v:
EMBO Molecular Medicine
EMBO molecular medicine 10(1), 32-47 (2018). doi:10.15252/emmm.201707825
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2018)
EMBO molecular medicine
EMBO molecular medicine, vol 10, iss 1
EMBO molecular medicine 10(1), 32-47 (2018). doi:10.15252/emmm.201707825
EMBO Molecular Medicine, Vol 10, Iss 1, Pp 32-47 (2018)
EMBO molecular medicine
EMBO molecular medicine, vol 10, iss 1
Alzheimer’s disease is a devastating neurodegenerative disease eventually leading to dementia. An effective treatment does not yet exist. Here we show that oral application of the compound anle138b restores hippocampal synaptic and transcriptional
Autor:
Fernando Teran Arce, Joon Lee, Ruth Nussinov, Hyunbum Jang, Alan L. Gillman, Bruce L. Kagan, Srinivasan Ramachandran
Publikováno v:
Biochemistry
Membrane permeability to ions and small molecules is believed to be a critical step in the pathology of Alzheimer’s disease (AD). Interactions of oligomers formed by amyloid-β (Aβ) peptides with the plasma cell membrane are believed to play a fun
Autor:
Ruth Nussinov, Hyunbum Jang, Srinivasan Ramachandran, Fernando Teran Arce, Joon Lee, Bruce L. Kagan, Alan L. Gillman
Publikováno v:
The Journal of Physical Chemistry. B
Among the family of Aβ peptides, pyroglutamate-modified Aβ (AβpE) peptides are particularly associated with cytotoxicity in Alzheimer's disease (AD). They represent the dominant fraction of Aβ oligomers in the brains of AD patients, but their acc