Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Fernando T. Ogata"'
Autor:
Flavio R. Palma, Diego R. Coelho, Kirthi Pulakanti, Marcelo J. Sakiyama, Yunping Huang, Fernando T. Ogata, Jeanne M. Danes, Alison Meyer, Cristina M. Furdui, Douglas R. Spitz, Ana P. Gomes, Benjamin N. Gantner, Sridhar Rao, Vadim Backman, Marcelo G. Bonini
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114415- (2024)
Externí odkaz:
https://doaj.org/article/425e2d4d57dd43c7b3fb3e7ae2f1fbd1
Publikováno v:
Cells, Vol 13, Iss 13, p 1105 (2024)
The cornea is continuously exposed to injuries, ranging from minor scratches to deep traumas. An effective healing mechanism is crucial for the cornea to restore its structure and function following major and minor insults. Transforming Growth Factor
Externí odkaz:
https://doaj.org/article/6d685a1590a34b4e8324862e30ae37b6
Publikováno v:
Redox Biology, Vol 43, Iss , Pp 101975- (2021)
Glutaredoxin, Grx, is a small protein containing an active site cysteine pair and was discovered in 1976 by Arne Holmgren. The Grx system, comprised of Grx, glutathione, glutathione reductase, and NADPH, was first described as an electron donor for R
Externí odkaz:
https://doaj.org/article/a38d669cac324ed98c7a6360f6307952
Publikováno v:
Biomedical Journal, Vol 40, Iss 4, Pp 189-199 (2017)
Accumulating mutations may drive cells into the acquisition of abnormal phenotypes that are characteristic of cancer cells. Cancer cells feature profound alterations in proliferation programs that result in a new population of cells that overrides no
Externí odkaz:
https://doaj.org/article/985582ff940c4461adb1a4aad7e0be4a
Autor:
Flavio R. Palma, Fernando T. Ogata, Diego R. Coelho, Kirthi Pulakanti, Alison Meyer, Yunping Huang, Jeanne M. Danes, Matthew J. Schipma, Cristina M. Furdui, Douglas R. Spitz, Benjamin N. Gantner, Sridhar Rao, Vadim Backman, Marcelo G. Bonini
Transcription stability enforces cellular identity and is tightly controlled by restrictions imposed on both transcription factor function and target gene accessibility. Progression of cancer to metastasis and multi-drug resistance requires fluid tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a8fa83fdfc2ea197f8e80401389d93
https://doi.org/10.1101/2022.12.01.517361
https://doi.org/10.1101/2022.12.01.517361
Autor:
Arnold Stern, Alex Y.S. Sato, Roberto J. Arai, Fernando T. Ogata, Lucia Coppo, Hugo P. Monteiro
Publikováno v:
Antioxidantsredox signaling. 36(13-15)
Significance: The epithelial-mesenchymal transition (EMT) is commonly associated with tumor metastasis. Oxidative and nitrosative stress are maintained in cancer cells and are involved in ...
Publikováno v:
Redox Biology, Vol 43, Iss, Pp 101975-(2021)
Glutaredoxin, Grx, is a small protein containing an active site cysteine pair and was discovered in 1976 by Arne Holmgren. The Grx system, comprised of Grx, glutathione, glutathione reductase, and NADPH, was first described as an electron donor for R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb98e41ca337e7d26680ab85951c426c
https://hdl.handle.net/10451/52340
https://hdl.handle.net/10451/52340
Publikováno v:
Free Radical Biology and Medicine. 134:350-358
The combination of ascorbate and menadione (VC:VK3 = 100:1) is an investigational treatment for cancer under clinical trials. Dehydroascorbic acid (DHA), the oxidized form of ascorbate, can be taken up by cells via glucose transporters, over-expresse
Autor:
S V Lucena, Tiago Rodrigues, Carolina M. Watashi, Marcelo Y. Icimoto, Gioconda E. D. D. Moura, Gustavo Monteiro Viana, Helena B. Nader, Hugo P. Monteiro, Fabiana Henriques Machado de Melo, Ivarne L.S. Tersariol, Fernando T. Ogata
Publikováno v:
Journal of Cellular Physiology. 233:3176-3194
We investigated the role of glycosaminoglycans (GAGs) in the regulation of endothelial nitric oxide synthase (eNOS) activity in wild-type CHO-K1 cells and in xylosyltransferase-deficient CHO-745 cells. GAGs inhibit the integrin/FAK/PI3K/AKT signaling
Publikováno v:
Biomedical Journal, Vol 40, Iss 4, Pp 189-199 (2017)
Accumulating mutations may drive cells into the acquisition of abnormal phenotypes that are characteristic of cancer cells. Cancer cells feature profound alterations in proliferation programs that result in a new population of cells that overrides no