Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Fernando Senjobe"'
Autor:
Clarety Kaseke, Ryan J. Park, Nishant K. Singh, Dylan Koundakjian, Arman Bashirova, Wilfredo F. Garcia Beltran, Overbeck C. Takou Mbah, Jiaqi Ma, Fernando Senjobe, Jonathan M. Urbach, Anusha Nathan, Elizabeth J. Rossin, Rhoda Tano-Menka, Ashok Khatri, Alicja Piechocka-Trocha, Michael T. Waring, Michael E. Birnbaum, Brian M. Baker, Mary Carrington, Bruce D. Walker, Gaurav D. Gaiha
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109378- (2021)
Summary: Defining factors that govern CD8+ T cell immunodominance is critical for the rational design of vaccines for viral pathogens. Here, we assess the contribution of human leukocyte antigen (HLA) class-I-peptide stability for 186 optimal HIV epi
Externí odkaz:
https://doaj.org/article/1b3dbca9ff374d98a372a84f9e322816
Autor:
Dibyendu Kumar Das, Uriel Bulow, William E Diehl, Natasha D Durham, Fernando Senjobe, Kartik Chandran, Jeremy Luban, James B Munro
Publikováno v:
PLoS Biology, Vol 18, Iss 2, p e3000626 (2020)
The Ebola virus (EBOV) envelope glycoprotein (GP) is a membrane fusion machine required for virus entry into cells. Following endocytosis of EBOV, the GP1 domain is cleaved by cellular cathepsins in acidic endosomes, removing the glycan cap and expos
Externí odkaz:
https://doaj.org/article/05e0e4e295874e04b946f426f10d4105
Autor:
Natasha D. Durham, Angela R. Howard, Ramesh Govindan, Fernando Senjobe, J. Maximilian Fels, William E. Diehl, Jeremy Luban, Kartik Chandran, James B. Munro
Publikováno v:
Viruses, Vol 12, Iss 1, p 103 (2020)
The Ebola virus (EBOV) envelope glycoprotein (GP) mediates the fusion of the virion membrane with the membrane of susceptible target cells during infection. While proteolytic cleavage of GP by endosomal cathepsins and binding of the cellular receptor
Externí odkaz:
https://doaj.org/article/bcdb787ba87e49aa8b5f334b67dd47fe
Autor:
Vivek Naranbhai, Anusha Nathan, Clarety Kaseke, Cristhian Berrios, Ashok Khatri, Shawn Choi, Matthew A. Getz, Rhoda Tano-Menka, Onosereme Ofoman, Alton Gayton, Fernando Senjobe, Kerri J. St Denis, Evan C. Lam, Wilfredo F. Garcia-Beltran, Alejandro B. Balazs, Bruce D. Walker, A. John Iafrate, Gaurav D. Gaiha
Publikováno v:
medRxiv
The SARS-CoV-2 Omicron variant (B.1.1.529) contains mutations that mediate escape from infection and vaccine-induced antibody responses, although the extent to which these substitutions in spike and non-spike proteins affect T cell recognition is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0dbfe84f2f53c41065f394c786fd72e
https://doi.org/10.1101/2022.01.04.21268586
https://doi.org/10.1101/2022.01.04.21268586
Autor:
Cory A. Perugino, Hang Liu, Jared Feldman, Blake M. Hauser, Catherine Jacob-Dolan, Anusha Nathan, Zezhou Zhou, Clarety Kaseke, Rhoda Tano-Menka, Matthew A. Getz, Fernando Senjobe, Cristhian Berrios, Onosereme Ofoman, Jacob E. Lemieux, Marcia B. Goldberg, Kerstin Nundel, Ann Moormann, Ann Marshak-Rothstein, John A. Iafrate, Gaurav Gaiha, Richelle Charles, Alejandro B. Balazs, Vivek Naranbhai, Aaron G. Schmidt, Shiv Pillai
In previously unvaccinated and uninfected individuals, non-RBD SARS-CoV-2 spike-specific B cells were prominent in two distinct, durable, resting, cross-reactive, “pre-existing” switched memory B cell compartments. While pre-existing RBD-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c444d4ac65de427e25dddb2163451afc
https://doi.org/10.1101/2021.12.30.21268554
https://doi.org/10.1101/2021.12.30.21268554
Publikováno v:
The Journal of Infectious Diseases
The development of an effective human immunodeficiency virus (HIV) cure is a critical global health priority. A major obstacle to this effort is the establishment of a latent reservoir of HIV infected cells, which necessitates lifelong therapy, causi
Autor:
Clarety, Kaseke, Ryan J, Park, Nishant K, Singh, Dylan, Koundakjian, Arman, Bashirova, Wilfredo F, Garcia Beltran, Overbeck C, Takou Mbah, Jiaqi, Ma, Fernando, Senjobe, Jonathan M, Urbach, Anusha, Nathan, Elizabeth J, Rossin, Rhoda, Tano-Menka, Ashok, Khatri, Alicja, Piechocka-Trocha, Michael T, Waring, Michael E, Birnbaum, Brian M, Baker, Mary, Carrington, Bruce D, Walker, Gaurav D, Gaiha
Publikováno v:
Cell Reports
Summary Defining factors that govern CD8+ T cell immunodominance is critical for the rational design of vaccines for viral pathogens. Here, we assess the contribution of human leukocyte antigen (HLA) class-I-peptide stability for 186 optimal HIV epit
Autor:
Overbeck C. Takou Mbah, Bruce D. Walker, Ryan J. Park, Mary Carrington, Ashok Khatri, Michael E. Birnbaum, Elizabeth J. Rossin, Arman Bashirova, Anusha Nathan, Fernando Senjobe, Michael T. Waring, Gaurav D. Gaiha, Jonathan M. Urbach, Nishant K. Singh, Rhoda Tano-Menka, Alicja Piechocka-Trocha, Wilfredo F. Garcia Beltran, Jiaqi Ma, Brian M. Baker, Dylan Koundakjian, Clarety Kaseke
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109378-(2021)
Summary: Defining factors that govern CD8+ T cell immunodominance is critical for the rational design of vaccines for viral pathogens. Here, we assess the contribution of human leukocyte antigen (HLA) class-I-peptide stability for 186 optimal HIV epi
Autor:
Natasha D. Durham, Jeremy Luban, Kartik Chandran, Uriel Bulow, Dibyendu Kumar Das, Fernando Senjobe, William E. Diehl, James B. Munro
Publikováno v:
PLoS Biology, Vol 18, Iss 2, p e3000626 (2020)
PLoS Biology
PLoS Biology
The Ebola virus (EBOV) envelope glycoprotein (GP) is a membrane fusion machine required for virus entry into cells. Following endocytosis of EBOV, the GP1 domain is cleaved by cellular cathepsins in acidic endosomes, removing the glycan cap and expos